Potentially inappropriate medications in elderly patients with heart failure: Beers Criteria‐based study

2020 ◽  
Vol 28 (6) ◽  
pp. 652-659 ◽  
Author(s):  
Mariam Zahwe ◽  
Hadi Skouri ◽  
Samar Rachidi ◽  
Maurice Khoury ◽  
Samar Noureddine ◽  
...  
2016 ◽  
Vol 30 (4) ◽  
pp. 419-424 ◽  
Author(s):  
Rebecca L. Salbu ◽  
Judith Feuer

The Beers Criteria identifies potentially inappropriate medications for patients who are 65 years of age and older. Initially published in 1991, the criteria have been updated multiple times, most recently in 2015. The Beers Criteria is a tool designed to alert health-care providers to the potential harms of specific medications so they may better tailor therapeutic regimens for their elderly patients. The expert panel of the 2015 update made changes to a number of previous recommendations and provided 2 new tables on select drug interactions and select medications requiring renal dose adjustments. The purpose of this review is to provide additional details and rationale behind selected noteworthy changes within the 2015 criteria. Specific information is provided on the changes in recommendations for the use of nitrofurantoin, antiarrhythmics, nonbenzodiazepine receptor agonist hypnotics, antipsychotics, and proton pump inhibitors in the elderly. Additional comparisons are made between the 2012 recommendations and newer recommendations made in the 2015 update, along with rationale for the change. This review will allow practitioners to apply the 2015 Beers Criteria and integrate their clinical judgment when evaluating and selecting drug therapy for elderly patients.


Author(s):  
Manoj H. Thummar ◽  
Tejas K. Patel ◽  
Varsha Y. Godbole ◽  
Manoj Kumar Saurabh

Background: Use of inappropriate medication is an important problem in present geriatric clinical practice. No specific potentially inappropriate medications (PIM) tools are available considering the availability of drugs in India. Aim and objective were to assess prevalence and pattern of potentially inappropriate medication (PIM) use in elderly inpatients by updated Beers criteria 2015 and EU(7) PIM list 2015.Methods: This cross-sectional study was carried out on medical records of elderly patients (≥65 yrs) admitted in the internal medicine wards and intensive care units (ICU) over a period of 6 weeks. The medications were evaluated for the PIM use as per Beers criteria and EU(7) PIM list.Results: A total of 225 patients (mean age- 71.48 yrs) were admitted in internal medicine wards and ICU during study period. Total 184 PIM belonged to 33 different medications were used during study period. The prevalence of PIM in internal medicine wards and ICUs were 51.96% and 57.14%, respectively. The prevalence of PIM was significantly higher with the EU(7) PIM list than Beers criteria (49.77% vs. 21.77%) [p<0.0001]. The commonly prescribed PIM were dextromethorphan (13.33%), ranitidine (11.11%) and glipizide (10.22%).Conclusions: Elderly patients frequently receive PIM. EU(7) PIM list identifies more PIM among elderly inpatients than Beers criteria.


Author(s):  
Hananeh Baradaran ◽  
Mohammad Nasirpur ◽  
Hadi Hamishehkar

Background: Pharmacotherapy in elderly patients has become a major concern due to their physiological changes, pharmacokinetic and pharmacodynamics variations and poly-pharmacy. In considering the global trend in population aging, we aim to evaluate the effect of “Beers Criteria” education on prescribing medications for elderly patients by General Practitioners (GPs). Methods: Thirty GPs with the highest number of prescriptions were included in this pilot study. All prescriptions written over a three-month period were considered, then prescriptions for geriatric patients were selected and evaluated. The GPs were trained using pamphlets and booklets which were prepared based on Beers 2015 explicit criteria. In order to evaluate the effect of education, appropriateness of prescriptions was analyzed before and 1 month following training. Results: Of 15,447 prescriptions selected during the first step, 1,281 prescriptions were related to geriatric patients in which the prevalence of inappropriate drug prescriptions was 37.3%. The most inappropriate medications identified were Bisacodyl, Alprazolam, and Hyoscyamine. While in the second step 1,055 of 15,154 prescriptions concerned the elderly and inappropriate drug prescription rate was noted as 23.6%. The most common inappropriate medications included Alprazolam, Amitriptyline, and Hyoscyamine. Based on our results, the prevalence of prescribing potentially inappropriate medications (PIMs) for elderly patients is high among GPs and educational interventions that raise awareness about “Beers Criteria” significantly reduce the prescribing PIMs. Conclusion: Given the importance of GP training programs in reducing inappropriate prescription rates among geriatric patients, it will be necessary for the National Committee of Rational Use of Drugs (NCRUD) to consider undertaking comprehensive educational strategies for reducing the prevalence of inappropriate medication use in elderly people.


Author(s):  
О. О. Кирилочев

Целью исследования явился анализ частоты назначений потенциально не рекомендованных лекарственных препаратов (ПНЛП) лицам пожилого возраста, находящимся на лечении в условиях психиатрического стационара. Данная работа проведена с помощью инструмента по борьбе с полипрагмазией - критериев Бирса, созданного под эгидой Американской гериатрической ассоциации. Исследование свидетельствует о высокой частоте применения ПНЛП следующих фармакологических групп: бензодиазепиновые производные, нестероидные противовоспалительные препараты (длительный приём), а также лекарственные средства с выраженным антихолинергическим потенциалом. Использование критериев Бирса может способствовать оптимизации лечения пожилых пациентов психиатрического профиля и повышению безопасности фармакотерапии. The study objective was to analyze the frequency of prescription of potentially inappropriate medications (PIMs) to elderly patients treated in a psychiatric in-patient setting. This study was carried out using AGS Beers criteria, an anti-polypharmacy tool developed under the auspices of the American Geriatric Association. The study indicates a high frequency of use of PIMs from the following pharmacological groups: benzodiazepine derivatives, non-steroidal anti-inflammatory drugs (long-term use), as well as drugs with significant anticholinergic potential. The AGS Beers criteria can help optimize the treatment for older psychiatric patients and increase the safety of pharmacotherapy.


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