scholarly journals Distinct contribution of protein kinase Cδand protein kinase Cεin the lifespan and immune response of human blood monocyte subpopulations

Immunology ◽  
2015 ◽  
Vol 144 (4) ◽  
pp. 611-620 ◽  
Author(s):  
Yadira Malavez ◽  
Oliver H. Voss ◽  
Martha Elba Gonzalez-Mejia ◽  
Arti Parihar ◽  
Andrea I. Doseff
Keyword(s):  
Immune Response ◽  
Protein Kinase ◽  
Human Blood ◽  
Blood Monocyte ◽  
Human Blood Monocyte ◽  
Monocyte Subpopulations

scholarly journals Differential interleukin-1 elaboration by density-defined human monocyte subpopulations

Blood ◽  
1985 ◽  
Vol 66 (2) ◽  
pp. 298-301
Author(s):  
JA Elias ◽  
P Chien ◽  
KM Gustilo ◽  
AD Schreiber
Keyword(s):  
Human Blood ◽  
Interleukin 1 ◽  
Human Monocyte ◽  
Mononuclear Phagocytes ◽  
Blood Monocyte ◽  
Thymocyte Proliferation ◽  
Percoll Gradients ◽  
Human Blood Monocyte ◽  
Monocytes And Macrophages ◽  
Monocyte Subpopulations

Interleukin-1 (IL-1) is an important immunoregulatory peptide produced by monocytes and macrophages. Because mononuclear phagocytes are morphologically and functionally heterogeneous, we examined whether they differ in their ability to elaborate IL-1. We used discontinuous Percoll gradients to obtain five density-defined human blood monocyte subpopulations. Unfractionated monocytes and their subsets were compared for their ability to stimulate thymocyte proliferation. Supernatants obtained from the denser monocytes consistently contained more IL-1 activity than did supernatants from the less dense cells. This difference in IL-1 activity was the result of differences in IL-1 elaboration, not the selective production of an inhibitor of IL-1- induced thymocyte proliferation. These data demonstrate that density- defined human monocyte subpopulations differ in their capacity to elaborate IL-1.

scholarly journals Differential interleukin-1 elaboration by density-defined human monocyte subpopulations

Blood ◽  
1985 ◽  
Vol 66 (2) ◽  
pp. 298-301 ◽  
Author(s):  
JA Elias ◽  
P Chien ◽  
KM Gustilo ◽  
AD Schreiber
Keyword(s):  
Human Blood ◽  
Interleukin 1 ◽  
Human Monocyte ◽  
Mononuclear Phagocytes ◽  
Blood Monocyte ◽  
Thymocyte Proliferation ◽  
Percoll Gradients ◽  
Human Blood Monocyte ◽  
Monocytes And Macrophages ◽  
Monocyte Subpopulations

Abstract Interleukin-1 (IL-1) is an important immunoregulatory peptide produced by monocytes and macrophages. Because mononuclear phagocytes are morphologically and functionally heterogeneous, we examined whether they differ in their ability to elaborate IL-1. We used discontinuous Percoll gradients to obtain five density-defined human blood monocyte subpopulations. Unfractionated monocytes and their subsets were compared for their ability to stimulate thymocyte proliferation. Supernatants obtained from the denser monocytes consistently contained more IL-1 activity than did supernatants from the less dense cells. This difference in IL-1 activity was the result of differences in IL-1 elaboration, not the selective production of an inhibitor of IL-1- induced thymocyte proliferation. These data demonstrate that density- defined human monocyte subpopulations differ in their capacity to elaborate IL-1.

Detection of Shedding of Human Blood Monocyte Fc Receptor during in vitro Culture

1981 ◽  
Vol 66 (2) ◽  
pp. 131-135 ◽  
Author(s):  
Neil E. Kay ◽  
Steven D. Douglas
Keyword(s):  
In Vitro Culture ◽  
Human Blood ◽  
Fc Receptor ◽  
Blood Monocyte ◽  
Human Blood Monocyte

Differentiation Of Human Blood Monocyte Subsets Into Fibrocytes Is Inhibited By Alveolar Environment During Acute Lung Injury

2012 ◽  
Author(s):  
Marc Garnier ◽  
Paer Abback ◽  
Pascale Piednoir ◽  
Mathieu Desmard ◽  
Lila Bouadma ◽  
...  
Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Human Blood ◽  
Blood Monocyte ◽  
Monocyte Subsets ◽  
Human Blood Monocyte

scholarly journals Human Blood Monocyte Subsets

2017 ◽  
Vol 37 (8) ◽  
pp. 1548-1558 ◽  
Author(s):  
Graham D. Thomas ◽  
Anouk A.J. Hamers ◽  
Catherine Nakao ◽  
Paola Marcovecchio ◽  
Angela M. Taylor ◽  
...  
Keyword(s):  
Human Blood ◽  
Blood Monocyte ◽  
Monocyte Subsets ◽  
Human Blood Monocyte

scholarly journals Autologous rosette formation by human blood monocyte-derived macrophages and lymphocytes

1999 ◽  
Vol 60 (4) ◽  
pp. 285-288 ◽  
Author(s):  
Humberto R.A. Cabral ◽  
Ivon T.C. Novak
Keyword(s):  
Human Blood ◽  
Rosette Formation ◽  
Blood Monocyte ◽  
Human Blood Monocyte

scholarly journals Characterization of a human blood monocyte subset with low peroxidase activity.

1983 ◽  
Vol 72 (3) ◽  
pp. 1093-1105 ◽  
Author(s):  
Y Akiyama ◽  
P J Miller ◽  
G B Thurman ◽  
R H Neubauer ◽  
C Oliver ◽  
...  
Keyword(s):  
Human Blood ◽  
Peroxidase Activity ◽  
Blood Monocyte ◽  
Monocyte Subset ◽  
Human Blood Monocyte
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