scholarly journals Respiratory virus infections in hospitalized children and adults in Lao PDR

2013 ◽  
Vol 7 (6) ◽  
pp. 1070-1078 ◽  
Author(s):  
Anne-Charlotte Sentilhes ◽  
Khamla Choumlivong ◽  
Olivier Celhay ◽  
Thongchanh Sisouk ◽  
Darouny Phonekeo ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Sunčanica Ljubin-Sternak ◽  
Tatjana Marijan ◽  
Irena Ivković-Jureković ◽  
Jasna Čepin-Bogović ◽  
Alenka Gagro ◽  
...  

The aim of this study was to determine the causative agent of acute respiratory infection (ARI) in hospitalized children, as well as investigate the characteristics of ARIs with single and multiple virus detection in two respiratory seasons. In 2010 and 2015, nasopharyngeal and pharyngeal swabs from a total of 134 children, admitted to the hospital due to ARI, were tested using multiplex PCR. Viral etiology was established in 81.3% of the patients. Coinfection with two viruses was diagnosed in 27.6% of the patients, and concurrent detection of three or more viruses was diagnosed in 12.8% of the patients. The most commonly diagnosed virus in both seasons combined was respiratory syncytial virus (RSV) (28.6%), followed by parainfluenza viruses (PIVs) types 1–3 (18.4%), rhinovirus (HRV) (14.3%), human metapneumovirus (10.1%), adenovirus (AdV) (7.1%), influenza viruses types A and B (4.8%), and coronaviruses (4.2%). In 2015, additional pathogens were investigated with the following detection rate: enterovirus (13.2%), bocavirus (HBoV) (10.5%), PIV-4 (2.6%), and parechovirus (1.3%). There were no statistical differences between single and multiple virus infection regarding patients age, localization of infection, and severity of disease(P>0.05). AdV, HRV, HBoV, and PIVs were significantly more often detected in multiple virus infections compared to the other respiratory viruses(P<0.001).


2019 ◽  
Vol 11 (5) ◽  
pp. 331-333 ◽  
Author(s):  
Peter J Hotez

Abstract Over the last decade we have seen extraordinary public health gains due to expansions in global vaccination programs led by United Nations (UN) agencies, including Gavi, the Vaccine Alliance, UNICEF and the WHO. These initiatives have reduced childhood deaths from measles, tetanus and other vaccine-preventable diseases by almost one half. There is additional excitement over the potential development and introduction of new vaccines to prevent highly lethal respiratory virus infections, as well as tuberculosis, malaria, HIV/AIDS and several neglected tropical diseases. However, these successes are under threat due to political instability, conflict and an accelerating antivaccine movement. New initiatives in vaccine diplomacy will be required to combat these challenges.


Author(s):  
Heather W Dolby ◽  
Philippe M D Potey ◽  
Annika Wilder-Smith ◽  
Sara Clohisey ◽  
Jonathan E Millar ◽  
...  

Abstract Pulmonary micro-thrombosis and vasculitis occur in fatal COVID-19. To determine if these processes occur in other life-threatening respiratory virus infections we identified autopsy studies of fatal influenza(n=455 patients), SARS(n=37), MERS(n=2), adenovirus(n=34) and RSV(n=30). Histological evidence of thrombosis was frequently present in adults with fatal influenza and SARS, with vasculitis also reported.


Author(s):  
Sinha Pranay ◽  
Katherine Reifler ◽  
Michael Rossi ◽  
Manish Sagar

Abstract Detection of diverse respiratory viruses in Boston was around 80% lower after practices were instituted to limit COVID-19 spread compared to the same time period during the previous five years. Continuing the strategies that lower COVID-19 dissemination may be useful in decreasing the incidence of other viral respiratory infections.


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