scholarly journals 15-Lipoxygenase-1 expression suppresses the invasive properties of colorectal carcinoma cell lines HCT-116 and HT-29

2009 ◽  
Vol 100 (12) ◽  
pp. 2283-2291 ◽  
Author(s):  
Ismail Çimen ◽  
Seda Tunçay ◽  
Sreeparna Banerjee
2018 ◽  
Vol 70 (7) ◽  
pp. 1126-1136 ◽  
Author(s):  
Yang-Ping Ding ◽  
Zi-Li Gao ◽  
Bing-Can Chen ◽  
Kanyasiri Rakariyatham ◽  
Hua-Yi Suo ◽  
...  

2011 ◽  
Vol 66 (9-10) ◽  
pp. 465-470 ◽  
Author(s):  
İlhan Işıkdağ ◽  
Yusuf Özkay ◽  
Zerrin İncesu ◽  
Gülşen Akalın

The discovery of DNA topoisomerases has added a new dimension to the study of anticancer drugs. Bisbenzimidazole derivatives are important compounds known as DNA topoisomerase I inhibitors. In the present study, some symmetrical bisbenzimidazole derivatives were synthesized and investigated for their anticancer activity. Anticancer activity screening was applied on HT-29 (colon carcinoma) and MCF-7 (breast carcinoma) cell lines by investigation of cytotoxicity, analysis of DNA synthesis, and DNA fragmentation assays. One of the seven compounds tested showed signifi cant cytotoxicity in both cell lines and caused DNA degradation in the HT-29 cell line.


2009 ◽  
Vol 125 (2) ◽  
pp. 297-307 ◽  
Author(s):  
Hui-Hua Zhang ◽  
Francesca Walker ◽  
Sara Kiflemariam ◽  
Robert H. Whitehead ◽  
David Williams ◽  
...  

Toxin Reviews ◽  
2019 ◽  
pp. 1-8
Author(s):  
Danijela D. Nikodijević ◽  
Milena G. Milutinović ◽  
Danijela M. Cvetković ◽  
Maja Đ. Ćupurdija ◽  
Milena M. Jovanović ◽  
...  

1988 ◽  
Vol 41 (2) ◽  
pp. 287-296 ◽  
Author(s):  
Deborah L. Trainer ◽  
Thomas Kline ◽  
Francis L. McCabe ◽  
Leo F. Faucette ◽  
John Feild ◽  
...  

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