Detection of metastatic tumour cells in routine bone marrow smears by immuno-alkaline phosphatase labelling with monoclonal antibodies

1985 ◽  
Vol 61 (1) ◽  
pp. 21-30 ◽  
Author(s):  
A. K. Ghosh ◽  
W. N. Erber ◽  
C. S. R. Hatton ◽  
N. T. J. O'Connor ◽  
B. Falini ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Alkaline Phosphatase ◽  
Monoclonal Antibodies ◽  
Tumour Cells ◽  
Metastatic Tumour

scholarly journals Immunocytochemical Labelling of Haematological Samples Using Monoclonal Antibodies

Cells ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 127
Author(s):  
Wendy N. Erber
Keyword(s):  
Bone Marrow ◽  
Alkaline Phosphatase ◽  
Monoclonal Antibodies ◽  
University Of Oxford ◽  
Alkaline Phosphatase Staining ◽  
Nuffield Department ◽  
Staining Methods ◽  
Biological Discovery ◽  
The University ◽  
Productive Time

I reflect on my experience working with David Y. Mason in the Leukaemia Research Laboratories in the Nuffield Department of Pathology at the University of Oxford in the early 1980s. This was soon after the first monoclonal antibodies had been produced, which led to an exciting and productive time in biological discovery and pathology diagnostics. A specific focus in the laboratory was the development of immunoenzymatic staining methods that would enable monoclonal antibodies to be applied in diagnostic practice. This paper describes the work that led to the performance of immuno-alkaline phosphatase staining on blood and bone marrow smears, the success of which changed leukaemia diagnosis.

Combinations of nonlabeled, 125I-Labeled, and Anti-Idiotypic Antiplacental Alkaline Phosphatase Monoclonal Antibodies at Experimental Radioimmunotargeting

1997 ◽  
Vol 38 (6) ◽  
pp. 1087-1093 ◽  
Author(s):  
R. Rossi Norrlund ◽  
D. Holback ◽  
L. Johansson ◽  
S. -O. Hietala ◽  
K. Riklund Åhlstrom
Keyword(s):  
Alkaline Phosphatase ◽  
Monoclonal Antibodies

Identification of tumour cells in CSF using monoclonal antibodies

Pathology ◽  
1984 ◽  
Vol 16 (4) ◽  
pp. 480
Author(s):  
W.W. Hancock ◽  
R.C. Atkins ◽  
G. Medley ◽  
M. Drake
Keyword(s):  
Monoclonal Antibodies ◽  
Tumour Cells

Long-term Follow-up of Bladder Cancer Patients with Disseminated Tumour Cells in Bone Marrow

2011 ◽  
Vol 60 (2) ◽  
pp. 231-238 ◽  
Author(s):  
Margitta Retz ◽  
Jens Rotering ◽  
Roman Nawroth ◽  
Alexander Buchner ◽  
Michael Stöckle ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bladder Cancer ◽  
Cancer Patients ◽  
Tumour Cells ◽  
Long Term Follow Up ◽  
Disseminated Tumour Cells

Apoptosis, cell proliferation and in vivo biological behaviour of primary and metastatic tumour cells of an AKR lymphoma variant

APOPTOSIS ◽  
1997 ◽  
Vol 2 (2) ◽  
pp. 214-220 ◽  
Author(s):  
N. Donin ◽  
D. Katzenelson ◽  
J. Ravia ◽  
J. Hiss ◽  
G. Schiby ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Tumour Cells ◽  
Metastatic Tumour ◽  
Biological Behaviour
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