scholarly journals Molecular remission without blood product support using all-trans retinoic acid (ATRA) induction and combined arsenic trioxide/ATRA consolidation in a Jehovah's Witness with de novo acute promyelocytic leukaemia

2000 ◽  
Vol 111 (4) ◽  
pp. 1103-1105 ◽  
Author(s):  
Glen A Kennedy ◽  
Paula Marlton ◽  
Ralph Cobcroft ◽  
Devinder Gill
Keyword(s):  
Retinoic Acid ◽  
Arsenic Trioxide ◽  
Acute Promyelocytic Leukaemia ◽  
Blood Product ◽  
De Novo ◽  
Promyelocytic Leukaemia ◽  
Molecular Remission ◽  
Jehovah's Witness ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid

scholarly journals Arsenic trioxide and all‐trans retinoic acid treatment for childhood acute promyelocytic leukaemia

2018 ◽  
Vol 185 (2) ◽  
pp. 360-363 ◽  
Author(s):  
Luisa Strocchio ◽  
Carmelo Gurnari ◽  
Nicola Santoro ◽  
Maria C. Putti ◽  
Concetta Micalizzi ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Arsenic Trioxide ◽  
Acute Promyelocytic Leukaemia ◽  
Acid Treatment ◽  
Promyelocytic Leukaemia ◽  
Retinoic Acid Treatment ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid

scholarly journals Tolerance to arsenic trioxide combined with all‐trans‐retinoic acid in children with acute promyelocytic leukaemia in France

2019 ◽  
Vol 188 (1) ◽  
pp. 170-173 ◽  
Author(s):  
Emmanuel Garcia Spezza ◽  
Benoit Brethon ◽  
Arnaud Petit ◽  
Franҫoise Mazingue ◽  
Virginie Gandemer ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Arsenic Trioxide ◽  
Acute Promyelocytic Leukaemia ◽  
Promyelocytic Leukaemia ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid

scholarly journals Severe Wernicke encephalopathy and acute pancreatitis due to all-trans-retinoic acid and arsenic trioxide during treatment of acute promyelocytic leukaemia: a case report

2020 ◽  
Vol 48 (9) ◽  
pp. 030006052095948 ◽  
Author(s):  
Yan Jiang ◽  
Linhua Ji
Keyword(s):  
Risk Factors ◽  
Acute Pancreatitis ◽  
Retinoic Acid ◽  
Arsenic Trioxide ◽  
Acute Promyelocytic Leukaemia ◽  
Promyelocytic Leukaemia ◽  
High Dose ◽  
Wernicke Encephalopathy ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid

A 55-year-old woman developed acute promyelocytic leukaemia during treatment with all-trans-retinoic acid and arsenic trioxide. Initially, she presented with symptoms of epigastric pain, vomiting, and nausea, and she developed acute pancreatitis. She was treated with parenteral nutritional supplementation for 20 days. However, the patient continued to develop refractory hyponatraemia, hypotension, and apathy. Finally, the patient was diagnosed with Wernicke encephalopathy (WE) using head magnetic resonance imaging. The patient underwent high-dose intravenous thiamine administration, and her symptoms were alleviated. WE is a rare adverse event during acute pancreatitis therapy. Acute pancreatitis that is caused by all-trans-retinoic acid and arsenic trioxide is a rare complication of acute promyelocytic leukaemia during chemotherapy. Further study is essential to improve our comprehension of the risk factors for complications in patients with acute promyelocytic leukaemia, considering that the associated complications were potentially caused by multiple etiological factors. A better understanding of these risk factors may help to improve the prognosis of patients with acute promyelocytic leukaemia at an early stage.

Sign in / Sign up

Export Citation Format

Share Document