scholarly journals The potential role of Aurora kinase inhibitors in haematological malignancies

2011 ◽  
Vol 155 (5) ◽  
pp. 561-579 ◽  
Author(s):  
Sherif S. Farag
Keyword(s):  
Potential Role ◽  
Kinase Inhibitors ◽  
Aurora Kinase ◽  
Haematological Malignancies ◽  
Aurora Kinase Inhibitors

Aurora Kinase Inhibitors in Head and Neck Cancer

2018 ◽  
Vol 18 (3) ◽  
pp. 199-213
Author(s):  
Guangying Qi ◽  
Jing Liu ◽  
Sisi Mi ◽  
Takaaki Tsunematsu ◽  
Shengjian Jin ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Therapy ◽  
Kinase Inhibitors ◽  
Biological Function ◽  
Aurora Kinase ◽  
Aurora Kinases ◽  
Related Research ◽  
Chemotherapy Drugs ◽  
Aurora Kinase Inhibitors

Aurora kinases are a group of serine/threonine kinases responsible for the regulation of mitosis. In recent years, with the increase in Aurora kinase-related research, the important role of Aurora kinases in tumorigenesis has been gradually recognized. Aurora kinases have been regarded as a new target for cancer therapy, resulting in the development of Aurora kinase inhibitors. The study and application of these small-molecule inhibitors, especially in combination with chemotherapy drugs, represent a new direction in cancer treatment. This paper reviews studies on Aurora kinases from recent years, including studies of their biological function, their relationship with tumor progression, and their inhibitors.

Discovery of novel 2,4-disubstituted pyrimidines as Aurora kinase inhibitors

2020 ◽  
Vol 30 (3) ◽  
pp. 126885 ◽  
Author(s):  
Yu Xu ◽  
Shu-Yi Hao ◽  
Xiu-Juan Zhang ◽  
Wen-Bo Li ◽  
Xue-Peng Qiao ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitors

scholarly journals Potential role of tyrosine kinase inhibitors during primary HIV-1 infection

2017 ◽  
Vol 15 (5) ◽  
pp. 421-423 ◽  
Author(s):  
Juan Ambrosioni ◽  
Mayte Coiras ◽  
José Alcamí ◽  
José M. Miró
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Potential Role ◽  
Kinase Inhibitors ◽  
Hiv 1
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