Asthma and allergic symptoms in relation to house dust endotoxin: Phase Two of the International Study on Asthma and Allergies in Childhood (ISAAC II)

Allergic rhinitis should be considered as a serious condition because it can affect the quality of life of patients. In manycases, the most common allergen is house dust mites (HDM). The purpose of this study was to describe the density ofhouse dust mites as triggers of allergic rhinitis in Pekanbaru orphanage children. This is a descriptive study with across sectional approach. Data obtained from interviews using the modified International Study of Asthma and Allergiesof Childhood (ISAAC) questionnaire to know the allergic rhinitis status and examination of house dust samples toidentify HDM in the parasitology laboratory. Sampling was carried out in 4 orphanages Pekanbaru. Allergic rhinitissymptoms were experienced by 81.2% of children in the orphanages and HDM was found with the mean density 9.11/g of dust. HDM was found in all four orphanages and was found to have a high incidence of allergic rhinitis.

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Molecular identification of the main allergens present in household dust of asthmatic patients

Ciência e Natura ◽

10.5902/2179460x41091 ◽

2020 ◽

Vol 42 ◽

pp. e17

Author(s):

Hyngrid Carolinne Soares Ferreira Moreira ◽

Sâmia Melo Santos ◽

Matheus Silva Alves ◽

Maryangela Godinho Pereira Bena ◽

Giselmo Pinheiro Lopes ◽

...

Keyword(s):

Allergic Rhinitis ◽

House Dust ◽

International Study ◽

Household Dust ◽

Chain Reactions ◽

Asthmatic Children ◽

Asthmatic Patients ◽

Polymerase Chain Reactions ◽

Predominant Factor ◽

Polymerase Chain

Introduction: The main aeroallergens present in house dust are the mites,Dermatophagoidespteronyssinus (Derp) andDermatophagoidesfarinae (Derf), and cockroaches,Periplanetaamericana (Pera). Objective: This work aims to genetically identify the allergens Derp, Derf, and Pera in household dust of asthmatic patients. Materials and methods: 29 patients, aged between 3 and 17 years, were classified as asthmatic or non-asthmatic according to the International Study of Asthma and Allergies in Childhood(ISAAC). Subjectscompleted a complementary questionnaire and skin hypersensitivity tests were performed. House dust was collected from these patients, filtered, and then DNA was extracted. Polymerase chain reactions were performed to identify Derp, Derf, and Pera in the samples. Results: There was an association between Pera sensitization and onset of asthma. There was also an association between the presence of Derp in the home of asthmatic patients and the worsening of symptoms, such as wheezing in the chest and allergic rhinitis. An association between the presence of Derf in house dust of asthmatic patients and the symptoms of allergic rhinitis was found. These data suggest that cockroach sensitization is a predominant factor in asthmatic children and the presence of mite allergens contributesto the worsening of asthma symptoms.

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ORGANOPHOSPHATE TRIESTERS IN HOUSE DUST AND ITS RELATION TO ALLERGIC SYMPTOMS

ISEE Conference Abstracts ◽

10.1289/isee.2011.00290 ◽

2011 ◽

Vol 2011 (1) ◽

Author(s):

Atsuko Araki ◽

Tomoya Takeda ◽

Ayako Kanazawa ◽

Ikue Saito ◽

Kanehisa Morimoto ◽

...

Keyword(s):

House Dust ◽

Allergic Symptoms ◽

Organophosphate Triesters

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The Association between Asthma and Allergic Symptoms in Children and Phthalates in House Dust: A Nested Case–Control Study

Environmental Health Perspectives ◽

10.1289/ehp.7187 ◽

2004 ◽

Vol 112 (14) ◽

pp. 1393-1397 ◽

Cited By ~ 539

Author(s):

Carl-Gustaf Bornehag ◽

Jan Sundell ◽

Charles J. Weschler ◽

Torben Sigsgaard ◽

Björn Lundgren ◽

...

Keyword(s):

House Dust ◽

Case Control Study ◽

Case Control ◽

Allergic Symptoms ◽

Nested Case Control ◽

Control Study

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Intranasal application of HDM/ISS conjugate attenuates the allergic symptoms in experimental allergic rhinitis sensitized to house dust mites

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2004.12.520 ◽

2005 ◽

Vol 115 (2) ◽

pp. S127

Author(s):

C. Rhee ◽

J. Mo ◽

K. Takabayashi ◽

S. Quan ◽

J. Park ◽

...

Keyword(s):

Allergic Rhinitis ◽

House Dust ◽

House Dust Mites ◽

Dust Mites ◽

Intranasal Application ◽

Allergic Symptoms ◽

Experimental Allergic

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Molecular identification of the main allergens present in household dust of asthmatic patients

Ciência e Natura ◽

10.5902/2179460x41093 ◽

2020 ◽

Vol 42 ◽

pp. e11

Author(s):

Hyngrid Carolinne Soares Ferreira Moreira ◽

Sâmia Melo Santos ◽

Matheus Silva Alves ◽

Maryangela Godinho Pereira Bena ◽

Giselmo Pinheiro Lopes ◽

...

Keyword(s):

Allergic Rhinitis ◽

House Dust ◽

International Study ◽

Household Dust ◽

Chain Reactions ◽

Asthmatic Children ◽

Asthmatic Patients ◽

Polymerase Chain Reactions ◽

Predominant Factor ◽

Polymerase Chain

The main aeroallergens present in house dust are the mites,Dermatophagoidespteronyssinus (Derp) andDermatophagoidesfarinae (Derf), and cockroaches,Periplanetaamericana (Pera). Objective: This work aims to genetically identify the allergens Derp, Derf, and Pera in household dust of asthmatic patients. Materials and methods: 29 patients, aged between 3 and 17 years, were classified as asthmatic or non-asthmatic according to the International Study of Asthma and Allergies in Childhood(ISAAC). Subjectscompleted a complementary questionnaire and skin hypersensitivity tests were performed. House dust was collected from these patients, filtered, and then DNA was extracted. Polymerase chain reactions were performed to identify Derp, Derf, and Pera in the samples. Results: There was an association between Pera sensitization and onset of asthma. There was also an association between the presence of Derp in the home of asthmatic patients and the worsening of symptoms, such as wheezing in the chest and allergic rhinitis. An association between the presence of Derf in house dust of asthmatic patients and the symptoms of allergic rhinitis was found. These data suggest that cockroach sensitization is a predominant factor in asthmatic children and the presence of mite allergens contributesto the worsening of asthma symptoms.

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