scholarly journals Effect of interferon-gamma priming on the activation of murine peritoneal macrophages to tumouricidal state by cisplatin, IL-1, and tumour necrosis factor (TNF): production of IL-1 and TNF

2008 ◽  
Vol 88 (2) ◽  
pp. 350-355 ◽  
Author(s):  
A. SODHI ◽  
R. K. SINGH ◽  
S. M. SINGH
Keyword(s):  
Tumour Necrosis Factor ◽  
Interferon Gamma ◽  
Tumour Necrosis ◽  
Peritoneal Macrophages ◽  
Murine Peritoneal Macrophages ◽  
Necrosis Factor

scholarly journals Effects of esculentoside A on turnour necrosis factor production by mice peritoneal macrophages

1992 ◽  
Vol 1 (6) ◽  
pp. 375-377 ◽  
Author(s):  
Fang Jun ◽  
Zheng Qin Yue ◽  
Wang Hong Bin ◽  
Ju Dian Wen ◽  
Yi Yang Hua
Keyword(s):  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Inflammatory Mediator ◽  
Platelet Activating Factor ◽  
Peritoneal Macrophages ◽  
Dependent Manner ◽  
Anti Inflammatory ◽  
Dose Dependent ◽  
Necrosis Factor ◽  
Inflammatory Effect

Esculentoside A (EsA) is a saponin isolated from the roots of Phytolacca esculenta. Previous experiments showed that it had strong anti-inflammatory effects. Tumour necrosis factor (TNF) is an important inflammatory mediator. In order to study the mechanism of the anti-inflammatory effect of EsA, it was determined whether TNF production from macrophages was altered by EsA under lipopolysaccharide (LPS) stimulated conditions. EsA was found to decrease both extracellular and cell associated TNF production in a dose dependent manner at concentrations higher than 1 μmol/l EsA. Previous studies have showed that EsA reduced the releasing of platelet activating factor (PAF) from rat macrophages. The reducing effects of EsA on the release of TNF and PAF may explain its anti-inflammatory effect.

scholarly journals Inhibition of Nitric Oxide and Tumour Necrosis Factor-α Production in Peritoneal Macrophages by Aspergillus nidulans Melanin

2013 ◽  
Vol 36 (12) ◽  
pp. 1915-1920 ◽  
Author(s):  
Rita de Cássia Ribeiro Gonçalves ◽  
Rodrigo Rezende Kitagawa ◽  
Maria Stella Gonçalves Raddi ◽  
Iracilda Zeppone Carlos ◽  
Sandra Regina Pombeiro-Sponchiado
Keyword(s):  
Nitric Oxide ◽  
Aspergillus Nidulans ◽  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Peritoneal Macrophages ◽  
Tumour Necrosis Factor Α ◽  
Factor Α ◽  
Necrosis Factor
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