scholarly journals Yersinia enterocolitica infection does not confer an increased risk of thyroid antibodies: evidence from a Danish twin study

2006 ◽  
Vol 146 (1) ◽  
pp. 32-38 ◽  
Author(s):  
P. S. Hansen ◽  
B. E. Wenzel ◽  
T. H. Brix ◽  
L. Hegedüs
1990 ◽  
Vol 28 (4) ◽  
pp. 382-396 ◽  
Author(s):  
Cheryl L Nickerson ◽  
Harvinder S Luthra ◽  
Suresh Savarirayan ◽  
Chella S David

2008 ◽  
Vol 172 (3) ◽  
pp. 671-680 ◽  
Author(s):  
Sabine Westphal ◽  
Andreas Lügering ◽  
Julia von Wedel ◽  
Christof von Eiff ◽  
Christian Maaser ◽  
...  

2000 ◽  
Vol 42 (4) ◽  
pp. 364-366 ◽  
Author(s):  
Akira Ehara ◽  
Kiyoshi Egawa ◽  
Fumiko Kuroki ◽  
Osamu Itakura and Masahito Okawa

1994 ◽  
Vol 13 (3) ◽  
pp. 233 ◽  
Author(s):  
Rosa Monno ◽  
Maria Antonietta Valenza ◽  
Michele Quarto ◽  
Vincenzo Sabato ◽  
Domenico De Mattia ◽  
...  

2019 ◽  
pp. 1-9 ◽  
Author(s):  
Carolina Martins Corcino ◽  
Tatiana Martins Benvenuto Louro Berbara ◽  
Débora Ayres Saraiva ◽  
Nathalie Anne de Oliveira e Silva de Morais ◽  
Annie Schtscherbyna ◽  
...  

AbstractObjectiveTo assess iodine status and its effects on maternal thyroid function throughout pregnancy.DesignIn the present prospective cohort study, three urinary samples were requested for urinary iodine concentration (UIC) determinations in both the first and third gestational trimesters. Serum thyrotropin (TSH) and free thyroxine (FT4) were analysed in both trimesters and thyroid antibodies were assessed once.SettingRio de Janeiro, Brazil.ParticipantsFirst-trimester pregnant women (n243), of whom 100 were re-evaluated during the third trimester.ResultsIodine sufficiency was found in the studied population (median UIC=216·7 µg/l). The first- and third-trimester median UIC was 221·0 and 208·0 µg/l, respectively. TSH levels (mean (sd)) were higher in the third trimester (1·08 (0·67)v. 1·67 (0·86) mIU/l;P<0·001), while FT4levels decreased significantly (1·18 (0·16)v. 0·88 (0·12) ng/dl;P<0·001), regardless the presence of iodine deficiency (UIC<150 µg/l) or circulating thyroid antibodies. UIC correlated (β; 95% CI) independently and negatively with age (–0·43; –0·71, –0·17) and positively with multiparity (0·15; 0·02, 0·28) and BMI (0·25; 0·00, 0·50). Furthermore, median UIC per pregnant woman tended to correlate positively with TSH (0·07; –0·01, 0·14). Women with median UIC≥250 µg/l and at least one sample ≥500 µg/l throughout pregnancy had a higher risk of subclinical hypothyroidism (OR=6·6; 95% CI 1·2, 37·4).ConclusionsIn this cohort with adequate iodine status during pregnancy, excessive UIC was associated with an increased risk of subclinical hypothyroidism.


Author(s):  
E. Galanakis ◽  
C. Perdikogianni ◽  
S. Maraki ◽  
E. Giannoussi ◽  
M. Kalmanti ◽  
...  

2010 ◽  
Vol 3 ◽  
pp. CPath.S4943 ◽  
Author(s):  
Geetanjali Gupta ◽  
Shailesh Kumar ◽  
Reecha Singh ◽  
Kathirvelu Shanmugasamy

Yersinia enterocolitica intussusception is rarely encountered in patients without an underlying susceptibility and is most frequently reported in iron-overloaded patients. This is thought to be related to the unusual use of iron by this microorganism. We present a case of a 5-year old child with intussusception of the terminal ileum caused by Y. enterocolitica whose past medical history was significant for sickle cell disease. This type of presentation is extremely rare. His monthly blood transfusions may have put him at risk for Y. enterocolitica enterocolitis. The pathogenesis of this disease relates to the role of iron as an essential growth factor for Y. enterocolitica, and this patient's transfusions left him in an iron overloaded state despite treatment with Deferoxamine. Our patient's unusual presentation of intusssuception was secondary to the mass effect caused by lymphoid hyperplasia, specifically hypertrophied Peyer's patches in the ileum caused by the Y. enterocolitica infection. We believe that our case demonstrates that Y. enterocolitica should be considered a possible pathogen in patients with sickle cell disease, especially if symptoms occur shortly after blood transfusion.


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