Pleomorphic adenoma of salivary gland: to what extent does fine needle aspiration cytology reflect histopathological features?

Cytopathology ◽  
2005 ◽  
Vol 16 (2) ◽  
pp. 65-70 ◽  
Author(s):  
D. K. Das ◽  
J. T. Anim
2018 ◽  
Vol 7 (1) ◽  
pp. 54-58
Author(s):  
Marcin Jarosław Kubiak ◽  
Dariusz Kaczmarczyk ◽  
Aleksandra Oleśna ◽  
Alina Morawiec-Sztandera

Objectives: Salivary gland tumors account for only 3% of head and neck tumors. Their character is mostly benign, although tumors of the submandibular gland are more often malignant. The purpose of this article was to evaluate the structure of patients operated due to submandibular gland tumor and to study the correlation between fine-needle aspiration cytology and postoperative histopathological examination. Methodology: We retrospectively analyzed the medical records of all patients with submandibular gland tumors. The collected data included the demographic structure, results of preoperative fine-needle aspiration cytology and postoperative histopathologic examination. Results: We analyzed 58 patients – 35 women and 23 men with a mean age of 56.6 years. The character of the lesion was benign in 45 cases and malignant in 13. The most frequent benign tumors were pleomorphic adenoma, inflammatory tumor and Warthin’s tumor, whereas most common malignancies were carcinoma planoepitheliale and lymphoma . There were four recurrences. Moreover, we compared results of preoperative fine-needle aspiration cytology and histopathological findings. The accuracy of this examination was almost 83%; 56% of incorrect results involved nondetection of malignancies. The sensitivity and specificity in the diagnosis of those tumors were 58.3% and 97.5%, respectively. Conclusions: The most common types of submandibular gland are pleomorphic adenoma and carcinoma planoepitheliale and lymphoma amongst malignancies. Fine-needle aspiration cytology is accurate in the preoperative diagnosis, mistakes are mostly caused by underdiagnosis of malignant tumors.


2020 ◽  
Vol 4 (12) ◽  
pp. 01-02
Author(s):  
Anju Khairwa

Pleomorphic adenoma (PA) is benign tumor of salivary gland. Pleomorphic adenoma contains both epithelial and myoepithelial elements and it arises from myoepithelial cells of salivary gland. The index study to describe rare case of pleomorphic adenoma of soft palate diagnosed by FNAC (fine needle aspiration cytology).


2020 ◽  
Vol 9 (1) ◽  
pp. PT06-PT08
Author(s):  
Santanu Kumar ◽  
Wakil Ahmad

Background: FNAC is a cytodiagnostic method based on the morphological findings of individual cells, group of cells, and microparticles of tissue, acquired using a needle. The role of FNAC for the diagnosis of salivary gland masses is well documented. The traditional open biopsy is no longer justified because of the risk of tumor spillage and damage to the facial nerve.Subjects and Methods:FNAC procedure was explained to the patient and patient was placed in a comfortable position. They were then subjected to fine needle aspiration cytology. Aspirations were carried out with 21 or 22 gauge needles of varying lengths with 10 ml syringes in a syringe holder after careful clinical examination of the lesion.Results:Chronic sialadenitis was the most common non-neoplastic lesion (13.2%) followed by cystic lesions (5.3%), acute on chronic sialadenitis (3.9%) and chronic granulomatous inflammation (2.6%). Pleomorphic adenoma (57.9%) was the most common benign neoplasm. Warthin’stumour accounted for (6.6%). Mucoepidermoid carcinoma was the most common malignant lesion (5.3%) followed by acinic cell carcinoma (1.3%), carcinoma-ex pleomorphic adenoma (1.3%) and adenoid cystic carcinoma (2.6%).Conclusion: Fine needle aspiration cytology of the salivary gland is a safe and reliable technique in the primary diagnosis of salivary gland lesions. Although, limitations are encountered while predicting specific lesions on cytology, especially when dealing with cystic and some malignant lesions.


2004 ◽  
Vol 48 (1) ◽  
pp. 78-82 ◽  
Author(s):  
Jesùs Vera-Alvarez ◽  
Miguel Marigil-Gómez ◽  
María Dolores García-Prats ◽  
Manuel Abascal-Agorreta ◽  
Miguel Lacasa-Laliena ◽  
...  

1970 ◽  
Vol 1 (2) ◽  
pp. 108-113 ◽  
Author(s):  
S Vaidya ◽  
A Sinha ◽  
S Narayan ◽  
S Adhikari ◽  
KC Sabira

Background: A wide variety of benign and malignant tumours originate in the salivary glands and insufficient tumour cells make their diagnosis difficult in some patients. The aim of this study was to evaluate the efficacy of fine-needle aspiration cytology in the diagnosis of salivary gland lesions and to correlate cytological findings with histopathology. Materials and Methods: This was a prospective study done from September 2002 to May 2004. Fine needle aspiration cytology was performed in 58 patients with clinically significant salivary gland masses. Results: Fine needle aspiration cytology categorized 67.24% of the salivary gland lesions as neoplastic and 32.76% as non-neoplastic lesions. Amongst the neoplastic lesions, 76.9% were benign and 23.1% were malignant cases. Histopathological examination revealed that 81.05% of the cases were benign and 18.95% were malignant. Fine needle aspiration cytology had a sensitivity, specificity and diagnostic accuracy of 81.82%, 100% and 96.55%, respectively. The positive predictive value and negative predictive value was 100% and 95.9%, respectively. Conclusion: Fine needle aspiration of the salivary gland is a safe and reliable technique in the primary diagnosis of salivary gland lesions. Although, limitations are encountered while predicting specific lesions on cytology, especially when dealing with cystic and some malignant lesions, this study has shown that fine needle aspiration cytology has a high sensitivity, specificity and diagnostic accuracy in diagnosing salivary gland lesions. Keywords: Salivary glands; Fine needle aspiration cytology; Histopathology DOI: http://dx.doi.org/10.3126/jpn.v1i2.5403 JPN 2011; 1(2): 108-113


2017 ◽  
Vol 4 (2) ◽  
pp. 307
Author(s):  
Anil R. Joshi ◽  
Dnyaneshwar S. Jadhav ◽  
Balaji D. Baste ◽  
Shweta K. Ranka

Background: Fine needle aspiration cytology (FNAC) of suspected salivary gland lesions has an established role in preoperative diagnosis and management of patients. However diverse morphological patterns and overlapping features make it a challenging job, to give a precise diagnosis at times.Methods: This was a prospective study done from October 2011 to October 2013. Fine needle aspiration cytology was performed in 64 patients with clinically significant salivary gland lesions.Results: Fine needle aspiration cytology categorized 38 (59.4%) of the salivary gland lesions as neoplastic and 26 (40.6 %) as non- neoplastic lesions. Amongst the neoplastic lesions, 86.9% were benign and 13.2% were malignant cases.Conclusions: FNAC of the salivary gland is simple, cheap, safe and reliable technique in the primary diagnosis of salivary gland lesions.


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