Plasma n-3 and n-6 fatty acids and the incidence of atrial fibrillation following coronary artery bypass graft surgery

2011 ◽  
Vol 41 (9) ◽  
pp. 995-1003 ◽  
Author(s):  
Gudrun V. Skuladottir ◽  
Ragnhildur Heidarsdottir ◽  
David O. Arnar ◽  
Bjarni Torfason ◽  
Vidar Edvardsson ◽  
...  
2015 ◽  
Vol 76 (2) ◽  
Author(s):  
Mario Sorice ◽  
Francesco Paolo Tritto ◽  
Chiara Sordelli ◽  
Rosario Gregorio ◽  
Luigi Piazza

Background: The aim of this study was to evaluate the efficacy of preoperative and postoperative therapy with n-3 polyunsaturated fatty acids in reducing the incidence of atrial fibrillation after coronary artery bypass graft surgery. Methods: 201 patients undergoing coronary artery bypass graft surgery were randomized to 1) a control group (105 patients), or 2) n-3 polyunsaturated fatty acids 2 g/day group (96 patients) for at least 5 days before surgery and until hospital discharge. Groups were further subdivided in four subgroups according to the operative technique: “off-pump” or “on-pump”. The primary end point was to evaluate the reduced incidence of postoperative in-hospital atrial fibrillation in the (N-3 PUFA) group. Secondary end points were the impact of the surgical technique on the incidence of postoperative arrhythmia and the impact of n-3 polyunsaturated fatty acids therapy on post-operative hospital length of stay. Results: The overall incidence of post-operative atrial fibrillation was 17.4% (35/201). The arrhythmia occurred in 11.4% (11/96) of the patients in therapy with n-3 polyunsaturated fatty acids and in 22.8% (24/105) in the control groups. In particular, the statistical analysis of subgroups showed a significant reduction of postoperative atrial fibrillation only in the group including patients treated with n-3 polyunsaturated fatty acids undergoing “on-pump” coronary artery bypass graft surgery. The length of hospital stay did not differ among all groups. Conclusions: N-3 polyunsaturated fatty acids administration significantly reduces the incidence of post-operative atrial fibrillation in patients undergoing “on-pump” coronary artery bypass graft surgery. N-3 polyunsaturated fatty acids therapy is not associated with a shorter hospital stay.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ali Vasheghani Farahani ◽  
Abbas Salehi Omran ◽  
Kyomars Abbasi ◽  
Ali Gholamrezaei ◽  
Pejman Mansouri ◽  
...  

2012 ◽  
Vol 204 (6) ◽  
pp. 862-867 ◽  
Author(s):  
Paul M. Bjordahl ◽  
Stephen D. Helmer ◽  
Dawn J. Gosnell ◽  
Gail E. Wemmer ◽  
Walter W. O'Hara ◽  
...  

2021 ◽  
Vol 85 (2) ◽  
pp. 4007-4012
Author(s):  
Ahmed Samy Alsadeq ◽  
Montaser Mostafa Alcekelly ◽  
Ahmed Shawky Shereef ◽  
Hala Gouda Abomandour

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