A man with generalized small white skin lesions and abdominal pain

2011 ◽  
Vol 50 (6) ◽  
pp. 726-729
Author(s):  
Tin Sik Cheng
Keyword(s):  
Abdominal Pain ◽  
Skin Lesions ◽  
White Skin

Steroid Effects on the Course of Abdominal Pain in Children With Henoch-Schonlein Purpura

PEDIATRICS ◽  
1987 ◽  
Vol 79 (6) ◽  
pp. 1018-1021
Author(s):  
NORMAN D. ROSENBLUM ◽  
HARLAND S. WINTER
Keyword(s):  
Abdominal Pain ◽  
Gastrointestinal Symptom ◽  
Systemic Vasculitis ◽  
Skin Lesions ◽  
Intestinal Bleeding ◽  
Controlled Trials ◽  
Henoch Schonlein Purpura ◽  
Intestinal Lesions ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Henoch-Schonlein purpura is a systemic vasculitis of unknown cause that is characterized primarily by abdominal pain, arthritis, and purpuric skin lesions. Abdominal pain is the most common gastrointestinal symptom, but intestinal bleeding and intussusception may occur. Previous studies have supported the use of steroids in managing the abdominal pain of Henoch-Schonlein purpura.1,2 Because there are no controlled trials using steroids in this disease, their value in affecting the intestinal lesions of Henoch-Schonlein purpura remains unknown. The purpose of this retrospective study was to assess the effect of corticosteroids on the outcome of abdominal pain in children with Henoch-Schonlein purpura. PATIENTS AND METHODS

Fever, Jaundice, Abdominal Pain, Skin Lesions, and Dark Urine for 2 Days

2015 ◽  
Vol 55 (3) ◽  
pp. 308-311
Author(s):  
Amir B. Orandi ◽  
Joshua W.M. Theisen ◽  
Jeffery Saland ◽  
T. Keefe Davis
Keyword(s):  
Abdominal Pain ◽  
Skin Lesions ◽  
Dark Urine

Case 33-2020: A 55-Year-Old Man with Abdominal Pain, Joint Swelling, and Skin Lesions

2020 ◽  
Vol 383 (17) ◽  
pp. 1664-1671
Author(s):  
Mariko R. Yasuda ◽  
Lauren A. Roller ◽  
Peter J. Fagenholz ◽  
Mai P. Hoang
Keyword(s):  
Abdominal Pain ◽  
Skin Lesions

scholarly journals A Case of Henoch-Schoenlein Purpura in Hemophilia

1977 ◽  
Author(s):  
A.L. Gonzaga ◽  
C.B. Azevedo ◽  
L.F. Baré
Keyword(s):  
Abdominal Pain ◽  
Surgical Intervention ◽  
Skin Lesions ◽  
Abdominal Discomfort ◽  
Hemophilia B ◽  
Moderate Intensity ◽  
Severe Hemophilia ◽  
Specific Therapy ◽  
Post Operative Period ◽  
Previous Infection

A 25-year-old male, white, with severe hemophilia B (F.IX < 1%) developed a rash of small erythematous macules, purpuric spots and petechia on the lower extremities. These skin lesions were discrete, not pruritic, not papular and with no areas of necrosis. No relationship to previous infection was determined. As the patient did not present any other clinical alteration, he was observed daily on an ambulatory basis in a four days’ period, without any medication. On the fifth day parallel to the disappearance of the skin lesions, the patient began to complain of abdominal pain, in crisis of moderate intensity. As the abdominal discomfort increased rapidly on the following 24 hours, we introduced specific therapy on an in-patient basis. The case evolved to an acute abdominal picture that required surgical intervention. The laparathomy resulted in large ressections of jejunum and ileum that showed large hemmorrhagic and necrotic areas. The post-operative period elapsed without incidents and the patient left the hospital in three weeks. This case that at the beginning could not give us a clear diagnosis of an anaphylactoid purpura shows us once more that in hemophilia, we must transfuse as early as possible.

Anemia, leukocytosis, abdominal pain, flushing, and bone and skin lesions

2012 ◽  
Vol 79 (6) ◽  
pp. 384-386
Author(s):  
Iván Álvarez-Twose ◽  
Sergio Vañó-Galván ◽  
Laura Sanchez-Muñoz ◽  
Soledad Fernandez-Zapardiel ◽  
Luis Escribano
Keyword(s):  
Abdominal Pain ◽  
Skin Lesions

scholarly journals Acute renal insufficiency and pancreatitis in a child with atypical Henoch–Schönlein purpura: efficacy of a single dose of cyclophosphamide

2018 ◽  
Vol 46 (12) ◽  
pp. 5285-5290 ◽  
Author(s):  
Maria Cristina Maggio ◽  
Silvio Maringhini ◽  
Saveria Sabrina Ragusa ◽  
Giovanni Corsello
Keyword(s):  
Abdominal Pain ◽  
Skin Lesions ◽  
Severe Anaemia ◽  
High Dose ◽  
Henoch Schonlein Purpura ◽  
Acute Renal Insufficiency ◽  
High Doses ◽  
Schonlein Purpura ◽  
Persistent Response ◽  
Henoch Schönlein Purpura

A 9-year-old boy with petechiae on the legs and abdominal pain was unsuccessfully treated with steroids. He was admitted to our hospital for the onset of fever, ecchymosis, and arthralgia. Skin lesions suggested vasculitis, but they were not typical of Henoch–Schönlein purpura. He showed ecchymosis of the scrotal bursa, diffusion of petechiae to the trunk and arms, vomiting, severe abdominal pain, oliguria with hyponatremia, hypoalbuminemia, low C3 levels, high levels of creatinine, blood urea nitrogen, and tubular enzymes, proteinuria, and glycosuria. The urinary sediment showed macrohaematuria, and hyaline and cellular casts. Ultrasound showed polyserositis. He was treated with intravenous furosemide, albumin, and methylprednisolone. He underwent colonoscopy and gastroscopy because of development of acute pancreatitis and severe anaemia. Typical lesions of Henoch–Schönlein purpura were observed in the small intestine and colon mucosa. He received three high doses of methylprednisolone, followed by intravenous cyclophosphamide. A dramatic and persistent response was observed after these doses. A single high dose of cyclophosphamide is appropriate in Henoch–Schönlein purpura with acute renal failure and severe pancreatitis that are non-responsive to high-dose steroids.

scholarly journals Magnetic Resonance Enterography Findings of Intestinal Behçet Disease in a Child

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Tommaso D’Angelo ◽  
Romina Gallizzi ◽  
Claudio Romano ◽  
Giuseppe Cicero ◽  
Silvio Mazziotti
Keyword(s):  
Abdominal Pain ◽  
Magnetic Resonance ◽  
Gastrointestinal Disease ◽  
Skin Lesions ◽  
Magnetic Resonance Enterography ◽  
Bowel Habit ◽  
Multisystem Disorder ◽  
Colicky Abdominal Pain ◽  
Oral Ulcers ◽  
Life Threatening

Behçet’s disease (BD) is a multisystem disorder of unknown aetiology, characterized by recurrent oral ulcers, genital ulcers, uveitis, skin lesions, and pathergy. Gastrointestinal disease outside the oral cavity is well recognized and usually takes the form of small intestinal ulcers, with the most significant lesions frequently occurring in the ileocaecal region. Symptoms usually include nausea, vomiting, colicky abdominal pain, and change in bowel habit and it is not unusual that patients may present late, with life-threatening complications requiring surgery. Diagnosis has been hindered for many years by limitations in imaging the small bowel and it is usually achieved by means of endoscopy and CT of the abdomen. Magnetic resonance enterography (MRE) is a relatively new technique, which has a high diagnostic rate in patients with Crohn’s disease (CD). Although many similarities between CD and intestinal BD have already been described in literature, the role of MRE in the evaluation of intestinal BD has never been defined up to now. We report a case of a 12-year-old female patient with diagnosis of BD who presented at our institution for recurrent colicky abdominal pain and diarrhoea. The patient underwent MRE that demonstrated the gastrointestinal involvement.

scholarly journals Familial Mediterranean Fever in Iran: A Report from FMF Registration Center

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Farhad Salehzadeh
Keyword(s):  
Abdominal Pain ◽  
Familial Mediterranean Fever ◽  
Mefv Gene ◽  
Positive Family History ◽  
Gene Mutations ◽  
Skin Lesions ◽  
Common Mutation ◽  
Clinical Criteria ◽  
Mediterranean Fever ◽  
The Mean

Background. Familial Mediterranean fever (FMF) is a periodic AR autoinflammatory disorder. This comprehensive study describes FMF in Iran as a country near Mediterranean area.Materials and Methods. From the country FMF registration center 403 patients according to Tel-Hashomer criteria enrolled this study, 239 patients had MEFV gene mutations analyses. Data, if needed, was analyzed by SPSS v20.Results. 175 patients (43.4%) were female and 228 patients (56.6%) were male. The mean age was 21.3 years. Abdominal pain was in 93.3% patients and 88.1% had fever. Abdominal pain was the main complaint of patients in (49.6%). The mean interval between attacks was36.5±29.6days and the mean duration of every episodes was43.3±34.5hours. 15.1% of patients had positive family history and 12.7% had previous surgery; in 52.3% of patients delay in diagnosis was more than three years. 12 common MEFV gene mutations were analyzed, 21.33% were without mutations, 39.7% had compound heterozygote, 25.52% showed heterozygous, and 13.38% showed homozygous results. The most common compound genotype was M694V-V726A (% 10.46) and in alleles M694V (% 20.9) and V726A (% 12.7) were the most frequent mutations, respectively.Conclusion. M694V was the most common mutation, and the most common compound genotype was M694V-V726A. Our genotype results are similar to Arabs and in some way to Armenians, erysipelas-like skin lesions are not common in this area, and clinical criteria are the preferred methods in diagnosis of FMF.

scholarly journals Sarcoidosis presenting with splenomegaly and abdominal pain: a case report

2012 ◽  
Vol 6 (3) ◽  
pp. 91-96
Author(s):  
Clara Faini ◽  
Natalia Manetti ◽  
Francesca Bucciero ◽  
Giulia Razzolini ◽  
Maria Marsico ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Lymph Nodes ◽  
Granulomatous Inflammation ◽  
Abdominal Ultrasound ◽  
Lung Parenchyma ◽  
Final Diagnosis ◽  
Skin Lesions ◽  
Mild Renal Impairment ◽  
Bilateral Hilar Lymphadenopathy ◽  
Noncaseating Granulomas

Sarcoidosis is a multisystemic disease of unknown aetiology characterized by proliferation of noncaseating granulomas at disease sites. It commonly affects young and middle-age adults and frequently presents with pulmonary infiltration, bilateral hilar lymphadenopathy, ocular and skin lesions. The liver, spleen, lymph nodes, salivary glands, heart, nervous system, muscles, bones, and other organs may also be involved. A diagnosis of the disorder usually requires the demonstration of typical lesions in more than one organ system and exclusion of other disorder known to cause granulomatous inflammation. We present the case of a young woman with abdominal pain and weight loss. The finding of splenomegaly by abdominal ultrasound and the presence of hypercalciuria, hypercalcemia and mild renal impairment led us to include sarcoidosis in the differential diagnosis. The final diagnosis was established by demonstration of involvement of lymph nodes and lung parenchyma on CT scan, and typical histology in bioptic specimens collected from bronchial mucosa.

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