All are equal, but some are more equal than others: social determinants of leisure time physical activity through the lens of intersectionality

Background To date, no research has investigated social determinants of leisure time physical activity through the lens of intersectionality in a low- and middle-income country. Therefore, the aim of this study was to explore the intersectionality in leisure time physical activity in a nationwide sample of Brazilian adults. Methods Data from the Brazilian National Health Survey conducted in 2013 were analysed (N = 58,429). Prevalence of sufficient leisure time physical activity (150+ minutes per week in moderate-to-vigorous physical activity) was estimated according to gender, racial identity, education and income, and according to multiple combinations of these sociodemographic characteristics (i.e., multiple jeopardy index). Results The prevalence of sufficient leisure time physical activity was 22.9% (95%CI: 22.3 to 23.6). Overall, the prevalence of sufficient leisure time physical activity was highest among men, individuals with white skin colour, and among those in the highest group of education and income. Among men, white, with a university degree and in the highest quartile of income (3% of the population), the prevalence of sufficient leisure time physical activity was 48%. Among non-white women with low education and low income (8.1% of the population), the prevalence of sufficient leisure time physical activity was 9.8%. Conclusion Informed by the theory of intersectionality, findings of this study have shown that intersections of gender, racial identity and socioeconomic position of the Brazilian society strongly influence leisure time physical activity at the individual level. Targeted interventions to increase leisure time physical activity should address the complexities of social status intersections.

The grape MYB24 mediates the coordination of light-induced terpene and flavonol accumulation in response to berry anthocyanin sunscreen depletion

The presence of naturally-occurring color mutants in plants has permitted the identification of many regulatory genes implicated in the synthesis of discrete metabolic compounds, mostly anthocyanins and carotenoids. Conversely, transcription factors that coordinate more than one specialized metabolic pathway seem challenging to screen from a forward genetics perspective. We explored the relationship between different branches of the phenylpropanoid and isoprenoid pathways while examining an infrequent berry skin color variegation in grapevine. Red and white berry skin sections were compared at the genetic, transcriptomic and metabolomic levels showing that, as in most cultivated white grape varieties, the uncolored skin section convened the non-functional alleles of the anthocyanin regulators MYBA1 and MYBA2, explaining the lack of pigments. In contrast, light-responsive flavonols and monoterpenes increased in anthocyanin-depleted areas. We disclosed an enrichment of the flavonol, terpene and carotenoid pathways among up-regulated genes from white-skin sections, accompanied by increased expressions of flavonol regulators and the still uncharacterized MYB24 gene. We used DAP-seq to examine the in vitro binding of affinity-purified MYB24 protein to genomic DNA and demonstrated its binding in the promoter regions of terpene (22) and carotenoid (6) genes, in addition to more than 30 photosynthesis/light-response genes, including the flavonol-regulator HY5 homologue (HYH). We confirmed the activation of TPS35 and HYH promoter:luciferase reporters in the presence of MYB24 and the grape bHLH MYC2, all of which correlate in their higher expression in white skin variegated sections. The integration of several datasets allowed to define a list of high confidence targets, suggesting MYB24 as a modulator of light responses including the synthesis of flavonoids (flavonols) and isoprenoids (terpenes, and putatively carotenoids). The correspondence between MYB24 and monoterpenes in all conditions surveyed implies that this regulatory network is broadly triggered towards berry ripening, and that the absence of anthocyanin sunscreens accelerates its activation most likely in a dose-dependent manner due to increased radiation exposure.

Islamic theism as a response to White Supremacy: The case of Shaikh Amadu Bamba Mbacké

This article examines Shaikh Amadu Bamba Mbacké and his theology as a cogent response to White Supremacy as expressed in French Colonization of Africa. White Supremacy has as its primary goal, the recreation of the whole world in the image of Whiteness upon the premise that the possession of White skin makes one inherently superior. Theism counters this ontological assault with an unabashed turn to a believer's God. Shaikh Amadu Bamba Mbacké's insistence on Islam counters White Supremacy thereby providing an ideological and metaphysical space for the non-whites of Senegal to exist without succumbing to the temptation to aspire to a Euro-centric ideal.

Minimal Erythema Dose Determination in Holstein Friesian Cattle

Cattle on pasture are continuously exposed to solar UV radiation, which has been associated with biological effects such as sunburn, photosensitization, squamous cell carcinoma, and cutaneous vitamin D3 production. The minimal erythema dose (MED) required to produce first-degree sunburn (erythema) is poorly researched in cattle. Since cattle are naturally covered with dense hair coats, the MED is influenced by the UV protection offered by the hair. The objective of this study was to determine the MED on intact-hair-covered (MED-H) and shaved white skin (MED-S) of Holstein Friesian cattle. Twenty-one Holstein Friesian cows and heifers were MED tested using a narrowband UV-B LED light (peak irradiance at 292 nm) on eight hair-covered and eight shaved areas over white skin previously unexposed to direct sunlight. Erythema was visually assessed after 24 h. The mean MED-H and MED-S were 5,595 and 329 J/m2, respectively. Heifers had a higher MED-H compared to cows, 7,600 and 4,969 J/m2, respectively. The mean UV transmittance of white cattle hair was 6.7%. MED-H was correlated with hair length (Spearman's rho = 0.76). A linear regression model showed that each millimeter of hair coat length increased the MED-H by 316 J/m2. In conclusion, this study provides a MED testing protocol for cattle and reports standardized values of MED for cattle on intact-hair-covered and shaved areas.

COLORISM IN TONI MORRISONS GOD HELP THE CHILD

The present paper has been specifically designed to scrutinize the aspect of colorism in Toni Morrisons well acclaimed novel God Help the Child. African American literature is an academic body of writing produced by African descendants residing in America. The literary canon of African- American literature emerged in late part of 18th century in oral forms like sermon, gospel, music, jazz, blues and spirituals. African American writers have deliberately expressed their painful agony, racial segregation, social injustice and ill treatment which they tolerated in white American society. Toni Morrison was a prolific female novelist of African-American literary writing. Morrisons eleventh novel God Help the Child prominently deals with colorism, racism and child abuse. Conceptually, the term Colorism was coined by Alice Walker to address the superiority of lighter or white skin over the dark. Colorism has its genetic roots in racism because without racism the standardization of color conflict would not be exist. The novel unfolds the story of Bride, also known as Lula Ann who is born with dark black color. She receives ill treatment by her own parents and gets negative rejection because of having black skin. Brides dark color ruins her golden childhood period. Louis Bridewell rejects Bride from accepting as his baby. Similarly, Sweetness breeds Bride with harsh treatment and cruelty. The research study will primarily focus on to address the color conflict faced by child protagonist Lula Ann.

Forecasting assessment of phenotypical features of ethnoteritorial groups of the Prykarpattya

The issue related to the study of anthroposcopic, anthropometric, dermatoglyphic parameters of the population of Ukraine to create regional gene pools remains relevant, because given the intensification of migration processes both within Ukraine and worldwide. The growing flow of global migration and assimilation creates all the conditions for the disappearance of pure ethnic groups and peoples. This work highlights the prospects for studying the ethnic and regional features of human anthroscopic parameters. The article presents the differential anthroscopic characteristics of Hutsul, Boyko, Lemko, Opollia, Pokuttia ethno-territorial groups. The goal of the work. To form anthroscopic portraits of Hutsul, Boyko, Lemko, Opollia, Pokuttia ethno-territorial groups in comparison with the control group of persons. Materials and methods. The material of the study was anthroscopic parameters of 480 males and females aged 18-59 years, belonging to the Hutsul, Boyko, Lemko, Opollia, Pokuttia and control groups, obtained by questionnaires using standardized methods proposed by Ginsburg BB (1963). The obtained data were subjected to statistical analysis. Results. Anthroposcopic portrait of the studied groups: Hutsul ethno-territorial group is characterized by dark skin tone, black straight hair, oval elongated straight face, dark brown or green-brown eyes, long narrow nose; Boyko ethno-territorial group is marked by white skin color, blond straight or wavy hair, round broad face, gray or dark brown eyes, wide straight nose; the Lemko ethno-territorial group is distinguished by white skin color, light straight or curly hair, oval elongated narrow long face, light brown and blue eyes, narrow straight nose; Opole ethno-territorial group is characterized by white skin color, light blond and dark blond wavy hair, round broad face, dark brown and light brown eyes, straight wide nose; The Pokut ethno-territorial group is distinguished by white skin, black and dark blond straight hair, an oval elongated narrow face, brown-green eyes, and a long narrow nose. Conclusion. We were able to apply the obtained results in practice, including in the set of identification features and developing an algorithm for rapid prediction of human outward signs.

Identification and Application of BhAPRR2 Controlling Peel Colour in Wax Gourd (Benincasa hispida)

Peel color is an important factor affecting commodity quality in vegetables; however, the genes controlling this trait remain unclear in wax gourd. Here, we used two F2 genetic segregation populations to explore the inheritance patterns and to clone the genes associated with green and white skin in wax gourd. The F2 and BC1 trait segregation ratios were 3:1 and 1:1, respectively, and the trait was controlled by nuclear genes. Bulked segregant analysis of both F2 plants revealed peaks on Chr5 exceeding the confidence interval. Additionally, 6,244 F2 plants were used to compress the candidate interval into a region of 179 Kb; one candidate gene, Bch05G003950 (BhAPRR2), encoding two-component response regulator-like protein Arabidopsis pseudo-response regulator2 (APRR2), which is involved in the regulation of peel color, was present in this interval. Two bases (GA) present in the coding sequence of BhAPRR2 in green-skinned wax gourd were absent from white-skinned wax gourd. The latter contained a frameshift mutation, a premature stop codon, and lacked 335 residues required for the protein functional region. The chlorophyll content and BhAPRR2 expression were significantly higher in green-skinned than in white-skinned wax gourd. Thus, BhAPRR2 may regulate the peel color of wax gourd. This study provides a theoretical foundation for further studies of the mechanism of gene regulation for the fruit peel color of wax gourd.

Comparison of Antibacterial and Antioxidant Properties of Red (cv. Negramaro) and White (cv. Fiano) Skin Pomace Extracts

Wine pomace has attracted the attention of the food industry, due to its high content in bioactive compounds, and its multiple healthy activities. In this work, whole and separated skin pomaces from fermented (red) and un-fermented (white) grape by-products were characterized for their antioxidant and antimicrobial activities in order to exploit them as functional food ingredient. Antioxidant activity, measured by both ORAC and TEAC assays, was higher in whole than in skin pomace extracts. The characterization of phenolic composition in whole and skin pomace extracts confirmed the peculiarity of some compounds such as anthocyanins (107.84 + 10.3 mg/g TP) in red skin pomace and a great amount of flavanols (80.73 + 4.04 mg/g TP) in white skin pomace. Whole and skin pomace extracts displayed the same antibacterial activity at 250 µg gallic acid equivalents (GAE)/mL. Red and white skin pomace extracts showed a Minimum Inhibitory Concentration (MIC) of 31.25–62.5 GAE/mL against Staphylococcus aureus and Enterococcus faecalis. Pseudomonas spp. were more sensitive to red skin pomace extracts rather than white skin pomace extracts. Given these results, both red and white pomace extracts could be exploited for future application in food, pharmaceutical and cosmetic industry.

Bridging The Gap: Demanding 1-1 Representation of Dark-Light Skin Tones Within Medical Lectures/Resources

Being a good physician means having the ability to recognize diseases in all kinds of individuals. This is especially true for skin lesions (e.g., acne, cancer), which present differently based on skin color and tone. Developing skin-tone-dependent diagnosing skills depends on the medical education (e.g., lectures, medical textbooks, and online board certification prep resources) and hands-on clinical experiences doctors receive. We find it alarming that medical students' gold standard resources overrepresent light skin and underrepresent dark skin to the point where many medical students can recognize a lesion on white skin but fail to recognize a similar lesion on dark skin. This lack of representation perpetuates race as a social determinant of health, leading to missed diagnoses and diagnosis at a later/worse stage in people of color. To combat this underrepresentation within medical education, we propose the Liaison Committee on Medical Education (LCME) amend Accreditation Standard 7: Curricular Content, Subsection 7.6: Cultural Competence and Health Care Disparities. The amendment is to include 1 of the 2 following policy changes, with preference for the top-down mandate: 1) Top-down Mandate: An objective measure and subsequent goal (1:1 representation) for the representation of skin of color within a school's medical lectures, which is evaluated by an LCME-approved curriculum committee and mandated for schools wishing to continue to be LCME accredited. 2) Bottom-up Individualized Institutional Goals: A requirement for schools to choose their own goal, create their committee, and evaluate their progress. These progress reports will be submitted to the LCME annually.