Safety and efficacy of a new extensively hydrolyzed formula for infants with cow’s milk protein allergy

2008 ◽  
Vol 19 (4) ◽  
pp. 348-354 ◽  
Author(s):  
B. Niggemann ◽  
A. von Berg ◽  
C. Bollrath ◽  
D. Berdel ◽  
U. Schauer ◽  
...  
Keyword(s):  
Milk Protein ◽  
Cow’S Milk ◽  
Safety And Efficacy ◽  
Cow's Milk ◽  
Cow’S Milk Protein ◽  
Hydrolyzed Formula

scholarly journals Formula Alternatives for Nutrition Therapy of Children with Cow’s Milk Protein Allergy

2021 ◽  
Author(s):  
Gennadiy A. Novik ◽  
Maria V. Zhdanova ◽  
Yulia O. Zaitseva ◽  
Anastasiia S. Demidova
Keyword(s):  
Milk Protein ◽  
Clinical Manifestations ◽  
Nutrition Therapy ◽  
Cow Milk ◽  
Cow’S Milk ◽  
Double Blind ◽  
Cow's Milk ◽  
Formula One ◽  
Cow’S Milk Protein ◽  
Hydrolyzed Formula

Well-recognized tactic for the management of formula-fed children with cow’s milk protein allergy (CMPA) is exclusion of whole cow milk protein and its replacement with extensively hydrolyzed or amino acid formula. One of the most topical issue is the choice of therapeutic formula for a child with CMPA. This article presents information about the clinical manifestations of CMPA and describes the principles of nutrition therapy. All the stages of preparation of adapted therapeutic formula are discussed in detail. It has been shown that the choice of therapeutic formula for a child with CMPA depends on the disease clinical manifestations, their severity, and the presence of comorbid conditions. Current requirements for extensively hydrolyzed formula are reduced to limitations in the size of peptides with immunoreactive properties and indicate the need for evidence of the clinical efficacy of such formula in double-blind placebo-controlled studies.

scholarly journals Knowledge and practice of pediatricians and nutritionists regarding treatment of cow’s milk protein allergy in infants

2018 ◽  
Vol 31 (6) ◽  
pp. 535-546
Author(s):  
Dayane Pêdra Batista de FARIA ◽  
Ana Paula Bidutte CORTEZ ◽  
Patrícia da Graça Leite SPERIDIÃO ◽  
Mauro Batista de MORAIS
Keyword(s):  
Milk Protein ◽  
Cow’S Milk ◽  
Milk Formula ◽  
Educational Strategies ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Cow's Milk ◽  
Allergy Treatment ◽  
Cow’S Milk Protein ◽  
Hydrolyzed Formula

ABSTRACT Objective This study evaluated the knowledge and practices of pediatricians and nutritionists about cow’s milk protein allergy in infants, with an emphasis on issues related to the exclusion diet and nutritional status. Methods A cross-sectional, descriptive study was performed with a convenience sample of 204 pediatricians and 202 nutritionists randomly invited in scientific events in the city of São Paulo, from November 2014 to March 2016. Results Between 1.5% and 21.0% of respondents indicated inadequate products for the treatment of cow’s milk protein allergy, including goat’s milk, beverages or juices based on soy extract, lactose-free milk formula and partially hydrolyzed formula. The daily calcium recommendation for children between zero and 36 months of age was correctly indicated by 27.0% of pediatricians and 46.0% of nutritionists (p=0.001). Additionally, 96.1% of pediatricians and 82.7% of dietitians (p<0.001) provided guidance on about labels of industrialized products. Conclusion Pediatricians and nutritionists present gaps in knowledge about cow’s milk protein allergy treatment in infants and educational strategies that increase the knowledge of the professionals are important for the management of cow’s milk protein allergy.

scholarly journals O5 The prevalence of cow’s milk protein allergy in infants with gastroschisis and intestinal failure type 2 and 3

2021 ◽  
Author(s):  
Kornilia Nikaki ◽  
Tracey Johnson ◽  
Haidee Norton ◽  
Gabis Chana ◽  
Amrita Garcha ◽  
...  
Keyword(s):  
Milk Protein ◽  
Intestinal Failure ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
Failure Type ◽  
Cow’S Milk Protein

scholarly journals Fecal Calprotectin and Eosinophil-Derived Neurotoxin in Children with Non-IgE-Mediated Cow’s Milk Protein Allergy

2021 ◽  
Vol 10 (8) ◽  
pp. 1595
Author(s):  
María Roca ◽  
Ester Donat ◽  
Ana Rodriguez Varela ◽  
Eva Carvajal ◽  
Francisco Cano ◽  
...  
Keyword(s):  
Milk Protein ◽  
Statistical Significance ◽  
Functional Gastrointestinal Disorders ◽  
Fecal Calprotectin ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
Young Infants ◽  
Healthy Infants ◽  
Ige Mediated ◽  
Cow’S Milk Protein

Our aim is to assess the efficacy of fecal calprotectin (fCP) and fecal eosinophil-derived neurotoxin (fEDN) as diagnostic markers of cow’s milk protein allergy (CMPA) and for monitoring the infants’ response to a non-IgE mediated cow’s milk protein (CMP)-free diet. We prospectively recruited infants aged 0 to 9 months. Stool samples were taken from 30 infants with CMPA, 19 with mild functional gastrointestinal disorders, 28 healthy infants, and 28 children who presented mild infections. Despite the fact that levels of fCP and fEDN in CMPA infants were higher than in healthy infants at month 0, differences for both parameters did not reach statistical significance (p-value 0.119 and 0.506). After 1 month of an elimination diet, no statistically significant differences in fCP with basal levels were found (p-values 0.184) in the CMPA group. We found a high variability in the fCP and fEDN levels of young infants, and discrepancies in individual behavior of these markers after a CMP-free diet was started. It seems that neither fCP nor fEDN levels are helpful to discriminate between healthy infants and those with signs or symptoms related to non-IgE-mediated CMPA. Additionally, it is debatable if on an individual basis, fCP or fEDN levels could be used for clinical follow-up and dietary compliance monitoring. However, prospective studies with larger populations are needed to draw robust conclusions.

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