scholarly journals Role of the Carboxy-Terminal Domain of Human Apolipoprotein AI in High-Density-Lipoprotein Metabolism. A Study Based on Deletion and Substitution Variants in Transgenic Mice

1997 ◽  
Vol 245 (3) ◽  
pp. 642-647 ◽  
Author(s):  
Paul Holvoet ◽  
Sophie Danloy ◽  
Desire Collen
Keyword(s):  
Transgenic Mice ◽  
High Density Lipoprotein ◽  
Lipoprotein Metabolism ◽  
Density Lipoprotein ◽  
High Density ◽  
Apolipoprotein Ai ◽  
Human Apolipoprotein ◽  
Carboxy Terminal Domain ◽  
Carboxy Terminal

scholarly journals Role of insulin in regulation of high density lipoprotein metabolism.

1986 ◽  
Vol 28 (1) ◽  
pp. 10-18
Author(s):  
A Golay ◽  
L Zech ◽  
M Z Shi ◽  
C Y Jeng ◽  
Y A Chiou ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Lipoprotein Metabolism ◽  
Density Lipoprotein ◽  
High Density

Hyperhomocysteinemia and high-density lipoprotein metabolism in cardiovascular disease

2007 ◽  
Vol 45 (12) ◽  
Author(s):  
Dan Liao ◽  
Xiaofeng Yang ◽  
Hong Wang
Keyword(s):  
Cardiovascular Disease ◽  
Coronary Heart Disease ◽  
High Density Lipoprotein ◽  
Independent Risk Factor ◽  
Lipoprotein Metabolism ◽  
Density Lipoprotein ◽  
Underlying Mechanism ◽  
High Density ◽  
Apolipoprotein Ai ◽  
Plasma High Density

AbstractHyperhomocysteinemia (HHcy) is a significant and independent risk factor for cardiovascular disease (CVD) and the underlying mechanism is unclear. We and others have reported that homocysteine (Hcy) is inversely correlated with plasma high-density lipoprotein cholesterol (HDL-C) and apolipoprotein AI (apoA-I) in patients with coronary heart disease (CHD). We confirmed this negative correlation in mice with targeted deletions of the genes for apolipoprotein E (apoE) and cystathionine β-synthase (CBS). Severe HHcy (plasma Hcy 210 μmol/L) accelerates spontaneous arthrosclerosis in the CBSClin Chem Lab Med 2007;45:1652–9.

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