Implementing a chronic disease strategy in two remote Indigenous Australian settings: A multi-method pilot evaluation

2008 ◽  
Vol 16 (2) ◽  
pp. 67-74 ◽  
Author(s):  
Peter d'Abbs ◽  
Barbara Schmidt ◽  
Kathryn Dougherty ◽  
Kate Senior
2019 ◽  
Vol 25 (1) ◽  
pp. 19 ◽  
Author(s):  
Meena Chandra ◽  
Anthea Duri ◽  
Mitchell Smith

The aim of this study is to compare the prevalence of chronic disease risk factors in humanitarian arrivals to Sydney, New South Wales (NSW) with the Australian Indigenous and non-Indigenous populations aged 35–44 years. Data on risk factors collected from 237 refugees presenting to the NSW Refugee Health Service (RHS) from January 2015 to August 2016 were retrospectively analysed and compared with data from the Australian Health Surveys, 2011–13 for the Indigenous and non-Indigenous Australian populations. This study found significantly higher levels of triglycerides (z=3; 95% CI, 0.16–0.26); hypertension (z=3.2; 95% CI, 0.17–0.29); and smoking (z=3.5; 95% CI, 0.27–0.33) in refugees compared with the general Australian population. The Indigenous population had significantly higher levels of triglycerides (z=4; 95% CI, 0.16–0.26); body mass indexes (BMIs) (z=3.3; 95% CI 0.58–0.72); and smoking (z=5.4; 95 CI 0.27–0.33) compared with refugees. Based on the study findings, screening for chronic disease risk factors from age 35 years may be warranted in all humanitarian arrivals to Australia, along with dietary and lifestyle advice.


2019 ◽  
Vol 22 (2) ◽  
pp. 79-87
Author(s):  
David A. Good ◽  
David L. Duffy ◽  
Manuela Good ◽  
Cheng Xia Guo ◽  
Frances Busfield ◽  
...  

AbstractType 2 diabetes (T2D) is a chronic disease that disproportionately affects Indigenous Australians. We have previously reported the localization of a novel T2D locus by linkage analysis to chromosome 2q24 in a large admixed Indigenous Australian pedigree (Busfield et al. (2002).American Journal of Human Genetics, 70, 349–357). Here we describe fine mapping of this region in this pedigree, with the identification of SNPs showing strong association with T2D: rs3845724 (diabetesp= 7 × 10−4), rs4668106 (diabetesp= 9 × 10−4) and rs529002 (plasma glucosep= 3 × 10−4). These associations were successfully replicated in an independent collection of Indigenous Australian T2D cases and controls. These SNPs all lie within the gene encoding ceramide synthase 6 (CERS6) and thus may regulate ceramide synthesis.


1962 ◽  
Vol 43 (5) ◽  
pp. 532-538 ◽  
Author(s):  
Clarence P. Alfrey ◽  
Lloyd G. Bartholomew ◽  
James C. Cain ◽  
Archie H. Baggbnstoss

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