Clinical manifestations and survival of patients with hepatocellular carcinoma and cardiac metastasis

2010 ◽  
Vol 25 (1) ◽  
pp. 150-155 ◽  
Author(s):  
Yu-Chun Liu ◽  
Yi-Lwun Ho ◽  
Guan-Tarn Huang ◽  
Ding-Shinn Chen ◽  
Jin-Chuan Sheu ◽  
...  
Author(s):  
Shang-Chin Huang ◽  
Sih-Han Liao ◽  
Tung-Hung Su ◽  
Yung-Ming Jeng ◽  
Jia-Horng Kao

Hepatology ◽  
2019 ◽  
Vol 69 (1) ◽  
pp. 209-221 ◽  
Author(s):  
Sih-Han Liao ◽  
Tung-Hung Su ◽  
Yung-Ming Jeng ◽  
Po-Chin Liang ◽  
Ding-Shinn Chen ◽  
...  

2020 ◽  
Vol 5 (2) ◽  

Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver and eighth-most common cancer. The most frequent sites of metastasis are the lungs, the bones, the lymphatics, and the brain. An isolated metastasis of a HCC to the right atrium and inferior vena cava (IVC) is extremely rare. Here we discuss a case of a 61-year-old female who presented with two weeks of generalized weakness and was found to have advanced stage HCC with metastasis to the IVC and right atrium of her heart. We recommend that echocardiography should be routinely performed for all patients with advanced HCC because if metastasis to the right atrium is not detected early enough, the clinical course will be complicated by many unexpected cardiovascular complications that can be fatal. Currently the prognosis for this disease is very poor so further investigation into surgical and medical treatments needs to occur.


2021 ◽  
Vol 11 ◽  
Author(s):  
Ruolan Xia ◽  
Yuwen Zhou ◽  
Yuqing Wang ◽  
Jiaming Yuan ◽  
Xuelei Ma

Hepatoid adenocarcinoma of the stomach (HAS) is a rare malignant tumor, accounting for only 0.17–15% of gastric cancers. Patients are often diagnosed at an advanced disease stage, and their symptoms are similar to conventional gastric cancer (CGC) without specific clinical manifestation. Morphologically, HAC has identical morphology and immunophenotype compared to hepatocellular carcinoma (HCC). This is considered to be an underestimation in diagnosis due to its rare incidence, and no consensus is reached regarding therapy. HAS generally presents with more aggressive behavior and worse prognosis than CGC. The present review summarizes the current literature and relevant knowledge to elaborate on the epidemic, potential mechanisms, clinical manifestations, diagnosis, management, and prognosis to help clinicians accurately diagnose and treat this malignant tumor.


2017 ◽  
Vol 11 (2) ◽  
pp. 416-421 ◽  
Author(s):  
Mashal Salehi ◽  
The Yee ◽  
Eric Alatevi ◽  
Yamin Thein

Intracavitary cardiac extension remains an unusual site of extrahepatic metastasis in patients with hepatocellular carcinoma. While patients can present with signs and symptoms suggestive of right-sided heart failure, it may be totally asymptomatic, which is very rare with only a few cases reported so far. Also, cardiac metastasis is of great prognostic importance as patients with intracardiac metastasis can have an extremely poor prognosis. Here, we present the case of a 52-year-old male patient with advanced hepatocellular carcinoma, with an incidentally found tumor thrombus extending from the inferior vena cava to the right atrium, protruding through the tricuspid valve into the right ventricle, on routine echocardiography. The patient did not have any signs or symptoms of heart involvement and unfortunately died on the 18th day of the hospital stay.


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