Objective: To explore the clinical value of carotid artery stent implantation (CAS) and carotid endarterectomy (CEA) in the treatment of patients with severe internal carotid artery stenosis. Methods: 88 patients with severe carotid artery stenosis who underwent CAS and CEA in the First People’s Hospital of Changde City (hereafter referred as “our hospital”) from January 2018 to December 2020 were selected as the research objects and divided into CAS group (n = 43) and CEA group (n = 45). To understand the clinical application value and feasibility of the two surgical schemes by comparing the general situation, cerebral blood flow, MMSE scale, MOCA scale score and serum miR-145, IGF1R levels of the two surgical schemes. Conclusions: CAS and CEA in the treatment of patients with severe internal carotid artery stenosis, have good curative effect, can effectively improve the patient's cerebral blood flow, regulate serum miR-145, IGF1R levels, promote the recovery of cognitive function, but relatively speaking, the incidence of stroke and hypotension after CAS is higher, and the incidence of hypertension after CEA is higher.
Distribution of cerebral blood flow in the caudate nucleus, lentiform nucleus and thalamus in patients with carotid artery stenosis
