Preparation and Evaluation of Hemoglobin-Polyethylene Glycol Conjugate (Pyridoxalated Polyethylene Glycol Hemoglobin) as an Oxygen-Carrying Resuscitation Fluid

1986 ◽  
Vol 10 (5) ◽  
pp. 411-416 ◽  
Author(s):  
Keiji Iwasaki ◽  
Yuji Iwashita
2008 ◽  
Vol 31 (5) ◽  
pp. 939-945 ◽  
Author(s):  
Madhuri Newa ◽  
Krishna Hari Bhandari ◽  
Dong Xun Li ◽  
Jong Oh Kim ◽  
Dong Sung Yoo ◽  
...  

Drug Delivery ◽  
2008 ◽  
Vol 15 (6) ◽  
pp. 355-364 ◽  
Author(s):  
Madhuri Newa ◽  
Krishna H. Bhandari ◽  
Jung-Ae Kim ◽  
Bong-Kyu Yoo ◽  
Han-Gon Choi ◽  
...  

2002 ◽  
Vol 70 (1) ◽  
pp. 77-86
Author(s):  
Baloǧlu B. ◽  
Kirkaǧaçhoǧlu O.

Conventional suppositories of tolmetin sodium were prepared by using two different types of Witepsol as an oily base and two different ratios of polyethylene glycol 400: polyethylene glycol 4000 as an water-soluble base. In addition, sustained- release suppositories were prepared by adding Eudragit L-100 ta the suppositories. The effects of the suppository base and the ratios of the polyethylene glycol 400: polyethylene glycols 4000 on the in vitro release characteristics were investigated. The release rate of tolmetin sodium from the conventional suppositories prepared with polyethylene glycol was slower than the other suppositories prepared with Witepsol. All of the suppositories with Eudragit L-100 showed slow-release profiles and the drug release rates clearly depended on the Eudragit L-100 content. When dissolution results were evaluated kinetically, zero order kinetic was observed with the sustained- release suppositories of tolmetin sodium prepared with polyethyleneglycol 400: polyethyleneglycol 4000 by adding Eudragit L-100.


2002 ◽  
Vol 122 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Yoshiteru WATANABE ◽  
Baku MUKAI ◽  
Ken-ichi KAWAMURA ◽  
Tatsuya ISHIKAWA ◽  
Michihiro NAMIKI ◽  
...  

Author(s):  
Kuixiong Gao ◽  
Randal E. Morris ◽  
Bruce F. Giffin ◽  
Robert R. Cardell

Several enzymes are involved in the regulation of anabolic and catabolic pathways of carbohydrate metabolism in liver parenchymal cells. The lobular distribution of glycogen synthase (GS), phosphoenolpyruvate carboxykinase (PEPCK) and glycogen phosphorylase (GP) was studied by immunocytochemistry using cryosections of normal fed and fasted rat liver. Since sections of tissue embedded in polyethylene glycol (PEG) show good morphological preservation and increased detectability for immunocytochemical localization of antigenic sites, and semithin sections of Visio-Bond (VB) embedded tissue provide higher resolution of cellular structure, we applied these techniques and immunogold-silver stain (IGSS) for a more accurate localization of hepatic carbohydrate metabolic enzymes.


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