Preparation and Evaluation of a 4-Branched Polyethylene Glycol Derivative Modified with Exendin-4 and Stearylamine for Extended Hypoglycemic Action

2010 ◽  
Vol 40 (3) ◽  
pp. 175-180
Author(s):  
In-Soo Kim ◽  
Kyung-Wan Ma ◽  
Sung-Ho Bae ◽  
Jeong-Hyun Yoon ◽  
Kyung-Taek Oh ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Branched Polyethylene ◽  
Hypoglycemic Action ◽  
Preparation And Evaluation

scholarly journals Preparation and Evaluation of Immediate Release Ibuprofen Solid Dispersions Using Polyethylene Glycol 4000

2008 ◽  
Vol 31 (5) ◽  
pp. 939-945 ◽  
Author(s):  
Madhuri Newa ◽  
Krishna Hari Bhandari ◽  
Dong Xun Li ◽  
Jong Oh Kim ◽  
Dong Sung Yoo ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Solid Dispersions ◽  
Immediate Release ◽  
Polyethylene Glycol 4000 ◽  
Preparation And Evaluation

scholarly journals Preparation and Evaluation of Fast Dissolving Ibuprofen-Polyethylene Glycol 6000 Solid Dispersions

Drug Delivery ◽  
2008 ◽  
Vol 15 (6) ◽  
pp. 355-364 ◽  
Author(s):  
Madhuri Newa ◽  
Krishna H. Bhandari ◽  
Jung-Ae Kim ◽  
Bong-Kyu Yoo ◽  
Han-Gon Choi ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Solid Dispersions ◽  
Polyethylene Glycol 6000 ◽  
Preparation And Evaluation

Immunogenicity of branched polyethylene glycol modified interferon alpha

2017 ◽  
Vol 40 (1) ◽  
pp. 35-42
Author(s):  
Weidong Zhou ◽  
Daru Lu ◽  
Xiaojin Liao ◽  
Lu Zhuang ◽  
Li Sun
Keyword(s):  
Polyethylene Glycol ◽  
Interferon Alpha ◽  
Branched Polyethylene

Rational Design of a Potent, Long-Lasting Form of Interferon:  A 40 kDa Branched Polyethylene Glycol-Conjugated Interferon α-2a for the Treatment of Hepatitis C

2001 ◽  
Vol 12 (2) ◽  
pp. 195-202 ◽  
Author(s):  
Pascal Bailon ◽  
Alicia Palleroni ◽  
Carol A. Schaffer ◽  
Cheryl L. Spence ◽  
Wen-Jian Fung ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Hepatitis C ◽  
Rational Design ◽  
Interferon Α ◽  
Branched Polyethylene

scholarly journals Branched polyethylene glycol/polypropylene micro-nanofiber nonwovens for fast liquid planar transmission

2019 ◽  
Vol 14 ◽  
pp. 155892501985079 ◽  
Author(s):  
Heng Zhang ◽  
Qi Zhen ◽  
Yong Liu ◽  
Rangtong Liu ◽  
Yifeng Zhang
Keyword(s):  
Polyethylene Glycol ◽  
Formation Mechanism ◽  
Wound Dressings ◽  
Engineering Applications ◽  
Liquid Filtration ◽  
Branched Polyethylene ◽  
Transmission Properties ◽  
Wide Range ◽  
Branched Structures ◽  
Die Temperature

The speed of liquid planar transmission plays a key role in engineering applications, including baby wipes, wound dressings, and liquid filtration. This article reported a novel branched nonwoven consisting of melt-blown polyethylene glycol/polypropylene micro- and nanofibers. The formation mechanism of branched structures as well as the liquid planar transmission properties of the prepared polyethylene glycol/polypropylene micro-nanofibrous nonwovens was discussed in detail. The results showed that the diameter of melt-blown fibers could be controlled by changing the percentage of polyethylene glycol (0–15 wt%) and die temperature (230°C–250°C). Furthermore, micro- and nanofibers, which had three types of size: >2 μm, 800 nm–2 μm, and <800 nm, formed a three-level branched network, which greatly improved the liquid planar transmission capacity. This work suggested that the branched micro/nanofiber nonwovens could be employed in a wide range of potential engineering applications.

scholarly journals Preparation and evaluation of tolmetin sodium conventional and sustained-release suppositories

2002 ◽  
Vol 70 (1) ◽  
pp. 77-86
Author(s):  
Baloǧlu B. ◽  
Kirkaǧaçhoǧlu O.
Keyword(s):  
Polyethylene Glycol ◽  
Sustained Release ◽  
In Vitro Release ◽  
Water Soluble ◽  
Order Kinetic ◽  
Polyethylene Glycol 400 ◽  
Suppository Base ◽  
Soluble Base ◽  
Preparation And Evaluation

Conventional suppositories of tolmetin sodium were prepared by using two different types of Witepsol as an oily base and two different ratios of polyethylene glycol 400: polyethylene glycol 4000 as an water-soluble base. In addition, sustained- release suppositories were prepared by adding Eudragit L-100 ta the suppositories. The effects of the suppository base and the ratios of the polyethylene glycol 400: polyethylene glycols 4000 on the in vitro release characteristics were investigated. The release rate of tolmetin sodium from the conventional suppositories prepared with polyethylene glycol was slower than the other suppositories prepared with Witepsol. All of the suppositories with Eudragit L-100 showed slow-release profiles and the drug release rates clearly depended on the Eudragit L-100 content. When dissolution results were evaluated kinetically, zero order kinetic was observed with the sustained- release suppositories of tolmetin sodium prepared with polyethyleneglycol 400: polyethyleneglycol 4000 by adding Eudragit L-100.

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