KN-62: A Specific Ca2+/calmodulin-dependent Protein Kinase Inhibitor as a Putative Function-searching Probe for Intracellular Signal Transduction

Intracellular Signal Transduction ◽

Dependent Protein ◽

Intracellular Signal

cAMP-dependent protein kinase and phosphoproteins in mammalian mitochondria. An extension of the cAMP-mediated intracellular signal transduction

FEBS Letters ◽

10.1016/s0014-5793(99)00070-8 ◽

1999 ◽

Vol 444 (2-3) ◽

pp. 245-249 ◽

Cited By ~ 66

Author(s):

Sergio Papa ◽

Anna Maria Sardanelli ◽

Salvatore Scacco ◽

Zuzana Technikova-Dobrova

Keyword(s):

Signal Transduction ◽

Protein Kinase ◽

Intracellular Signal Transduction ◽

Mammalian Mitochondria ◽

Dependent Protein ◽

Intracellular Signal

Glutamic acid 203 of the cAMP-dependent protein kinase catalytic subunit participates in the inhibition by two isoforms of the protein kinase inhibitor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)42170-3 ◽

1994 ◽

Vol 269 (3) ◽

pp. 2316-2323

Author(s):

E.J. Baude ◽

S.S. Dignam ◽

S.R. Olsen ◽

E.M. Reimann ◽

M.D. Uhler

Keyword(s):

Protein Kinase ◽

Glutamic Acid ◽

Kinase Inhibitor ◽

Catalytic Subunit ◽

Effect of the thermostable protein kinase inhibitor on intracellular localization of the catalytic subunit of cAMP-dependent protein kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)41857-1 ◽

1992 ◽

Vol 267 (24) ◽

pp. 16824-16828 ◽

Cited By ~ 2

Author(s):

D.A. Fantozzi ◽

S.S. Taylor ◽

P.W. Howard ◽

R.A. Maurer ◽

J.R. Feramisco ◽

...

Keyword(s):

Protein Kinase ◽

Kinase Inhibitor ◽

Intracellular Localization ◽

Catalytic Subunit ◽

Dependent Protein ◽

Thermostable Protein

M3814, a DNA-dependent Protein Kinase Inhibitor (DNA-PKi), Potentiates the Effect of Ionizing Radiation (IR) in Xenotransplanted Tumors in Nude Mice

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2015.12.268 ◽

2016 ◽

Vol 94 (4) ◽

pp. 940-941 ◽

Cited By ~ 8

Author(s):

L. Damstrup ◽

A. Zimmerman ◽

C. Sirrenberg ◽

F. Zenke ◽

L. Vassilev

Keyword(s):

Protein Kinase ◽

Ionizing Radiation ◽

Nude Mice ◽

Kinase Inhibitor ◽

CC-115, a Dual Mammalian Target of Rapamycin/DNA-Dependent Protein Kinase Inhibitor in Clinical Trial, Is a Substrate of ATP-Binding Cassette G2, a Risk Factor for CC-115 Resistance

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.119.258392 ◽

2019 ◽

Vol 371 (2) ◽

pp. 320-326 ◽

Cited By ~ 4

Author(s):

Jenny Beebe ◽

Jian-Ting Zhang

Keyword(s):

Clinical Trial ◽

Risk Factor ◽

Protein Kinase ◽

Kinase Inhibitor ◽

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin ◽

Atp Binding ◽

Inhibition of M3 muscarinic acetylcholine receptor-mediated Ca2+ influx and intracellular Ca2+ mobilization in neuroblastoma cells by the Ca2+calmodulin-dependent protein kinase inhibitor 1-[N, O-bis(5-isoquinolinesulfonyl) -N-methyl-1-trosyl]-4-phenylpiperazine (KN-62)

Biochemical Pharmacology ◽

10.1016/s0006-2952(97)00089-0 ◽

1997 ◽

Vol 53 (8) ◽

pp. 1107-1114 ◽

Cited By ~ 8

Author(s):

Henry L. Puhl ◽

Padma S. Roman ◽

Carol L. Williams ◽

S. Aronstam Robert

Keyword(s):

Protein Kinase ◽

Acetylcholine Receptor ◽

Kinase Inhibitor ◽

Neuroblastoma Cells ◽

Muscarinic Acetylcholine Receptor ◽

Muscarinic Acetylcholine ◽

M3 Muscarinic Acetylcholine Receptor ◽

A Novel Calcium-Dependent Protein Kinase Inhibitor as a Lead Compound for Treating Cryptosporidiosis

The Journal of Infectious Diseases ◽

10.1093/infdis/jit327 ◽

2013 ◽

Vol 208 (8) ◽

pp. 1342-1348 ◽

Cited By ~ 50

Author(s):

Alejandro Castellanos-Gonzalez ◽

A. Clinton White ◽

Kayode K. Ojo ◽

Rama S. R. Vidadala ◽

Zhongsheng Zhang ◽

...

Keyword(s):

Protein Kinase ◽

Kinase Inhibitor ◽

Lead Compound ◽

Calcium Dependent ◽

Dependent Protein ◽

Calcium Dependent Protein Kinase

Radio-sensitization of human leukaemic MOLT-4 cells by DNA-dependent protein kinase inhibitor, NU7441

Radiation and Environmental Biophysics ◽

10.1007/s00411-013-0494-5 ◽

2013 ◽

Vol 53 (1) ◽

pp. 83-92 ◽

Cited By ~ 14

Author(s):

Ales Tichy ◽

Kamila Durisova ◽

Barbora Salovska ◽

Jaroslav Pejchal ◽

Lenka Zarybnicka ◽

...

Keyword(s):

Protein Kinase ◽

Kinase Inhibitor ◽

Modulation of Ca2+ fluxes in isolated platelet vesicles: effects of cAMP-dependent protein kinase and protein kinase inhibitor on Ca2+ sequestration and release

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ◽

10.1016/0167-4889(87)90049-8 ◽

1987 ◽

Vol 931 (1) ◽

pp. 49-58 ◽

Cited By ~ 25

Author(s):

Joann M. Hettasch ◽

Guy C. Le Breton

Keyword(s):

Protein Kinase ◽

Kinase Inhibitor ◽

An ether-based peptide analog as c-AMP-dependent protein kinase inhibitor/substrate

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(01)80153-0 ◽

1994 ◽

Vol 4 (4) ◽

pp. 553-556 ◽

Cited By ~ 1

Author(s):

Mengfei Ho ◽

Amy Uhrin ◽

Michelle Huang

Keyword(s):

Protein Kinase ◽

Kinase Inhibitor ◽

Peptide Analog ◽