Treatment of Nursing Home Residents with Dementia and Lower Respiratory Tract Infection in the United States and the Netherlands: An Ocean Apart

2004 ◽  
Vol 52 (5) ◽  
pp. 691-699 ◽  
Author(s):  
Jenny T. Van Der Steen ◽  
Robin L. Kruse ◽  
Marcel E. Ooms ◽  
Miel W. Ribbe ◽  
Gerrit Van Der Wal ◽  
...  
JAMA ◽  
2001 ◽  
Vol 286 (19) ◽  
pp. 2427 ◽  
Author(s):  
David R. Mehr ◽  
Ellen F. Binder ◽  
Robin L. Kruse ◽  
Steven C. Zweig ◽  
Richard Madsen ◽  
...  

PEDIATRICS ◽  
2009 ◽  
Vol 124 (4) ◽  
pp. e768-e776 ◽  
Author(s):  
R. J. Singleton ◽  
E. A. Wirsing ◽  
D. L. Haberling ◽  
K. Y. Christensen ◽  
C. D. Paddock ◽  
...  

2019 ◽  
Vol 14 (11) ◽  
pp. 688-690 ◽  
Author(s):  
Sophie E Katz ◽  
Laura F Sartoni ◽  
Derek J Williams

Procalcitonin (PCT) is a biomarker that has shown promise to identify bacterial etiology in acute infections, including bacterial lower respiratory tract infection (LRTI). In 2017, the United States Food and Drug Administration (FDA) approved the use of PCT as a diagnostic aid to guide the decisions around antibiotic therapy in acute LRTI.1 Although most of the data supporting the use of PCT for LRTI stems from adult studies, the high disease burden, predominance of viral etiologies, and frequent diagnostic uncertainty resulting in antibiotic overuse make pediatric LRTI an ideal target for the use of PCT as a diagnostic aid. This review evaluates and summarizes the current evidence regarding the role of PCT in the clinical care of pediatric LRTI, including its use in guiding antibiotic use and prognosticating disease severity.


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