Detailed immunophenotypic characterization of different major and minor subsets of peripheral blood cells in patients with paroxysmal nocturnal hemoglobinuria

Transfusion ◽  
2008 ◽  
Vol 48 (7) ◽  
pp. 1403-1414 ◽  
Author(s):  
Pilar M. Hernndez-Campo ◽  
Julia Almeida ◽  
Mara J. Acevedo ◽  
Mara L. Snchez ◽  
Ignacio Alberca ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Blood Cells ◽  
Paroxysmal Nocturnal Hemoglobinuria ◽  
Peripheral Blood Cells

Morphological and morphometric characterization of agoutis' peripheral blood cells (Dasyprocta prymnolopha, wagler, 1831) raised in captivity

2011 ◽  
Vol 75 (3) ◽  
pp. 374-378 ◽  
Author(s):  
Airton Mendes Conde Júnior ◽  
Eunice Anita De Moura Fortes ◽  
Danilo José Ayres De Menezes ◽  
Luana De Oliveira Lopes ◽  
Maria Acelina Martins De Carvalho
Keyword(s):  
Peripheral Blood ◽  
Blood Cells ◽  
Peripheral Blood Cells ◽  
In Captivity ◽  
Morphometric Characterization

scholarly journals Characterization of lymphocyte subsets in peripheral blood cells of children with EV71 infection

2020 ◽  
Vol 53 (5) ◽  
pp. 705-714 ◽  
Author(s):  
Ming-Qi Zhao ◽  
Li-Hua Wang ◽  
Guang-Wan Lian ◽  
Zheng-Fang Lin ◽  
Ying-Hua Li ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Blood Cells ◽  
Lymphocyte Subsets ◽  
Ev71 Infection ◽  
Peripheral Blood Cells

Characterization of mast-cell tryptase-expressing peripheral blood cells as basophils

2002 ◽  
Vol 109 (2) ◽  
pp. 287-293 ◽  
Author(s):  
Barbara Foster ◽  
Lawrence B. Schwartz ◽  
Gilles Devouassoux ◽  
Dean D. Metcalfe ◽  
Calman Prussin
Keyword(s):  
Mast Cell ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Peripheral Blood Cells ◽  
Mast Cell Tryptase

Increased expression of anti-apoptosis genes in peripheral blood cells from patients with paroxysmal nocturnal hemoglobinuria

2003 ◽  
Vol 78 (4) ◽  
pp. 291-294 ◽  
Author(s):  
Matthew M. Heeney ◽  
Susan M. Ormsbee ◽  
M. Anthony Moody ◽  
Thad A. Howard ◽  
Carlos M. DeCastro ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Blood Cells ◽  
Paroxysmal Nocturnal Hemoglobinuria ◽  
Peripheral Blood Cells

scholarly journals Peripheral blood cells are predominantly chimeric of affected and normal cells in patients with paroxysmal nocturnal hemoglobinuria: simultaneous investigation on clonality and expression of glycophosphatidylinositol-anchored proteins

Blood ◽  
1994 ◽  
Vol 83 (3) ◽  
pp. 853-859 ◽  
Author(s):  
H Ohashi ◽  
T Hotta ◽  
A Ichikawa ◽  
T Kinoshita ◽  
R Taguchi ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Paroxysmal Nocturnal Hemoglobinuria ◽  
Southern Hybridization ◽  
Peripheral Blood Cells ◽  
Chain Reaction ◽  
Normal Cells ◽  
Clonality Analysis ◽  
Polymerase Chain

To investigate clonal compositions of hematologic cells in paroxysmal nocturnal hemoglobinuria (PNH), we analyzed peripheral blood (PB) cells of 12 female patients with PNH, by clonality analysis using X-chromosome inactivation and assessment of expression of glycophosphatidylinositol-anchored proteins (GPI-APs) by flow cytometry. Southern hybridization showed that granulocytes were monoclonal in three and polyclonal in eight patients, respectively, whereas lymphocytes were polyclonal in all nine patients examined. Expressions of CD16 and CD59 on granulocytes varied greatly in seven patients examined. Clonality analysis of granulocytes by the polymerase chain reaction showed that CD59-and CD59low+ cells were monoclonal, whereas CD59+ cells were polyclonal. It was shown that PB cells are predominantly chimeric of clonal (GPI-AP-or GPI-APlow+) and nonclonal (GPI-AP+) cells in PNH, and that degrees of chimerism differ greatly from patient to patient.

scholarly journals Peripheral blood cells are predominantly chimeric of affected and normal cells in patients with paroxysmal nocturnal hemoglobinuria: simultaneous investigation on clonality and expression of glycophosphatidylinositol-anchored proteins

Blood ◽  
1994 ◽  
Vol 83 (3) ◽  
pp. 853-859 ◽  
Author(s):  
H Ohashi ◽  
T Hotta ◽  
A Ichikawa ◽  
T Kinoshita ◽  
R Taguchi ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Paroxysmal Nocturnal Hemoglobinuria ◽  
Southern Hybridization ◽  
Peripheral Blood Cells ◽  
Chain Reaction ◽  
Normal Cells ◽  
Clonality Analysis ◽  
Polymerase Chain

Abstract To investigate clonal compositions of hematologic cells in paroxysmal nocturnal hemoglobinuria (PNH), we analyzed peripheral blood (PB) cells of 12 female patients with PNH, by clonality analysis using X-chromosome inactivation and assessment of expression of glycophosphatidylinositol-anchored proteins (GPI-APs) by flow cytometry. Southern hybridization showed that granulocytes were monoclonal in three and polyclonal in eight patients, respectively, whereas lymphocytes were polyclonal in all nine patients examined. Expressions of CD16 and CD59 on granulocytes varied greatly in seven patients examined. Clonality analysis of granulocytes by the polymerase chain reaction showed that CD59-and CD59low+ cells were monoclonal, whereas CD59+ cells were polyclonal. It was shown that PB cells are predominantly chimeric of clonal (GPI-AP-or GPI-APlow+) and nonclonal (GPI-AP+) cells in PNH, and that degrees of chimerism differ greatly from patient to patient.

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