Effect of Hyper- and Hypocapnia on Cerebral Arterial Compliance in Normal Subjects

2011 ◽  
Vol 21 (2) ◽  
pp. 121-125 ◽  
Author(s):  
Emmanuel Carrera ◽  
Dong-Joo Kim ◽  
Gianluca Castellani ◽  
Christian Zweifel ◽  
Peter Smielewski ◽  
...  
Keyword(s):  
Arterial Compliance ◽  
Normal Subjects ◽  
Cerebral Arterial Compliance

scholarly journals Cardiorespiratory fitness is associated with increased middle cerebral arterial compliance and decreased cerebral blood flow in young healthy adults: A pulsed ASL MRI study

2019 ◽  
Vol 40 (9) ◽  
pp. 1879-1889 ◽  
Author(s):  
Hannah V Furby ◽  
Esther AH Warnert ◽  
Christopher J Marley ◽  
Damian M Bailey ◽  
Richard G Wise
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Cardiorespiratory Fitness ◽  
Grey Matter ◽  
Arterial Compliance ◽  
Cerebral Arteries ◽  
Early Adulthood ◽  
Cerebrovascular Reactivity ◽  
Beneficial Effects ◽  
Cerebral Arterial Compliance

Cardiorespiratory fitness is thought to have beneficial effects on systemic vascular health, in part, by decreasing arterial stiffness. However, in the absence of non-invasive methods, it remains unknown whether this effect extends to the cerebrovasculature. The present study uses a novel pulsed arterial spin labelling (pASL) technique to explore the relationship between cardiorespiratory fitness and arterial compliance of the middle cerebral arteries (MCAC). Other markers of cerebrovascular health, including resting cerebral blood flow (CBF) and cerebrovascular reactivity to CO2 (CVRCO2) were also investigated. Eleven healthy males aged 21 ± 2 years with varying levels of cardiorespiratory fitness (maximal oxygen uptake ([Formula: see text]O2MAX) 38–76 ml/min/kg) underwent MRI scanning at 3 Tesla. Higher [Formula: see text]O2MAX was associated with greater MCAC (R2 = 0.64, p < 0.01) and lower resting grey matter CBF (R2 = 0.75, p < 0.01). However, [Formula: see text]O2MAX was not predictive of global grey matter BOLD-based CVR (R2 = 0.47, p = 0.17) or CBF-based CVR (R2 = 0.19, p = 0.21). The current experiment builds upon the established benefits of exercise on arterial compliance in the systemic vasculature, by showing that increased cardiorespiratory fitness is associated with greater cerebral arterial compliance in early adulthood.

Dependency of arterial compliance on circulating neuroendocrine and metabol factors in normal subjects

1992 ◽  
Vol 69 (16) ◽  
pp. 1340-1344 ◽  
Author(s):  
Joel M. Neutel ◽  
David H.G. Smith ◽  
William F. Graettinger ◽  
Michael A. Weber
Keyword(s):  
Arterial Compliance ◽  
Normal Subjects

REPRODUCIBILITY OF ARTERIAL COMPLIANCE AND CAROTID WALL THICKNESS MEASUREMENTS IN NORMAL SUBJECTS

1998 ◽  
Vol 25 (7-8) ◽  
pp. 618-620 ◽  
Author(s):  
Yu-Lu Liang ◽  
James D. Cameron ◽  
Helena Teede ◽  
Dimitra Kotsopoulos ◽  
Barry P. McGrath
Keyword(s):  
Wall Thickness ◽  
Arterial Compliance ◽  
Normal Subjects ◽  
Carotid Wall ◽  
Thickness Measurements

Estimation of Forearm Arterial Compliance in Essential Hypertension: A Preliminary Report

1982 ◽  
Vol 63 (s8) ◽  
pp. 87s-88s ◽  
Author(s):  
A. CH. Simon ◽  
J. A. Levenson ◽  
S. P. Laurent ◽  
M. E. Safar
Keyword(s):  
Blood Flow ◽  
Essential Hypertension ◽  
Brachial Artery ◽  
Diastolic Pressure ◽  
Arterial Compliance ◽  
Normal Subjects ◽  
Arterial System ◽  
Flow Measurements ◽  
Blood Pressures ◽  
Blood Flow Measurements

1. Simultaneous brachial artery pressure and blood flow measurements were made in 21 men, including six normal subjects and 15 patients with essential hypertension of the same age and diastolic pressure at the time of investigation. 2. Blood flow was evaluated by means of a pulsed Doppler device with a double transducer probe, enabling a precise evaluation of the calibre of the brachial artery. From analysis of the pressure-flow curves during diastole, forearm arterial compliance was estimated by using an original first-order model of the forearm arterial system. 3. Forearm arterial compliance was significantly decreased in hypertensive subjects. 4. Since patients and hypertensive subjects had similar blood pressures, the results indicate that the reduced forearm compliance was independent of blood pressure per se but may reflect in hypertensive subjects adaptive changes in the walls of peripheral large arteries.

Relationship of arterial compliance to baroreflex function in hypertensive patients

1993 ◽  
Vol 265 (1) ◽  
pp. H232-H237 ◽  
Author(s):  
S. G. Lage ◽  
J. F. Polak ◽  
D. H. O'Leary ◽  
M. A. Creager
Keyword(s):  
Blood Pressure ◽  
Arterial Compliance ◽  
Normal Subjects ◽  
Arterial Baroreflex ◽  
Arterial Diameter ◽  
Hypertensive Patients ◽  
Baroreflex Function ◽  
Normotensive Subjects ◽  
Relationship Of ◽  
Carotid Arterial

The objectives of this study were to determine whether carotid arterial compliance is reduced in patients with hypertension and to assess whether reduced arterial compliance is related to abnormal arterial baroreflex function. Accordingly, concurrent measurements of carotid arterial diameter (via computerized high resolution B-mode ultrasonography) and blood pressure were made to determine carotid arterial compliance in 23 normotensive and 16 age-matched hypertensive patients. In addition, arterial baroreflex function was assessed in 12 of the normal subjects and nine of the hypertensive patients by measuring the infusions of nitroprusside and phenylephrine. Compared with the normotensive subjects, the patients with hypertension had reduced compliance (5.9 +/- 0.7 vs. 16.6 +/- 1.8 10(-7) m2/kPa, mean +/- SE, P < 0.001). The baroreflex slope relating the change in R-R interval to the change in systolic blood pressure during the drug infusions was less in the hypertensive than normotensive subjects (12.3 +/- 2 vs. 18.9 +/- 2 ms/mmHg, P < 0.05). Consequently, when both normotensive and hypertensive subjects were considered, there was a significant correlation between the baroreflex slope and compliance (r = 0.53, P < 0.05). However, there was no correlation between the baroreflex slope and compliance within either the normotensive group (r = 0.04, P = NS) or the hypertensive group (r = 0.43, P = NS) when analyzed separately. There was a significant correlation between age and compliance (r = -0.48, P < 0.01) but not between age and baroreflex function.(ABSTRACT TRUNCATED AT 250 WORDS)

An evaluation of large arteries compliance in man

1979 ◽  
Vol 237 (5) ◽  
pp. H550-H554 ◽  
Author(s):  
A. C. Simon ◽  
M. E. Safar ◽  
J. A. Levenson ◽  
G. M. London ◽  
B. I. Levy ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vascular System ◽  
Diastolic Pressure ◽  
Arterial Compliance ◽  
Peripheral Resistance ◽  
Normal Subjects ◽  
K Value ◽  
Hypertensive Patients ◽  
Large Arteries ◽  
The Relationship

Cardiac output, blood pressure, and the characteristics of diastolic pressure decay were studied in 12 normal subjects and 23 sustained hypertensive patients of the same age. In normal subjects and in hypertensives, analysis of the diastolic decay showed that i) the form of the decay approximated a simple monoexponential curve during the last two-thirds of the diastolic segment, and ii) the time constant (t) of the curve was positively correlated with the total peripheral resistance (TPR), with an intercept of nearly zero. The validity of the relationship t = K x TPR was demonstrated both in groups of patients and also in individuals. Using a simple model for the vascular system, the K value was identified as the large arteries compliance and could thus be calculated in each individual. The values of arterial compliance was 1.26 +/- 0.04 ml.mmHg-1.m-2 in normal subjects and was significantly reduced in hypertensive patients (0.88 +/- 0.02 ml.mmHg=1.m-2,. P less than 0.001).

scholarly journals Radial Artery Compliance in Patients with Peripheral Vascular Disease

1997 ◽  
Vol 2 (1) ◽  
pp. 8-12 ◽  
Author(s):  
Maria Catalano ◽  
Giovanni Scandale ◽  
Tao Jun ◽  
Marzio Minola ◽  
Martino Recchia ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Radial Artery ◽  
Blood Pressure Monitoring ◽  
Arterial Compliance ◽  
Normal Subjects ◽  
Inhomogeneous System ◽  
Peripheral Vascular ◽  
Arterial Tree

Compliance in largely central arteries of patients with peripheral vascular disease (PVD) has been reported to be reduced. However, the arterial tree is an inhomogeneous system, and there remains uncertainty about whether the peripheral arteries (e.g. the medium-sized muscular radial artery) undergo a similar change to the central arteries. The aim of this study was to investigate the radial artery elasticity in 19 patients with PVD compared with 18 normal subjects of comparable age and sex. Using a noninvasive high-resolution echo-tracking device coupled to a photoplethysmograph (Finapres system) allowing simultaneous arterial diameter and finger blood pressure monitoring, we measured the radial artery compliance by determining the diameter–pressure, compliance–pressure and distensibility–pressure curves. The results showed that the diameter of the radial artery was similar in the two groups, but that the compliance and distensibility were not further reduced in patients with PVD than in the normal controls at 100 mmHg and for a common blood pressure range. The present studies demonstrate that in patients with PVD the radial arterial compliance is not reduced, which indicates that the change in arterial elasticity is not identical. The potential mechanisms involved in this change in radial artery compliance are discussed.

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