Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): case report with nodal and diffuse muco-cutaneous involvement

1998 ◽  
Vol 25 (10) ◽  
pp. 563-567 ◽  
Author(s):  
D. Innocenzi ◽  
V. Silipo ◽  
S. Giombini ◽  
L Ruco ◽  
C. Bosman ◽  
...  
Author(s):  
Zephania Abraham ◽  
Zerd Francis ◽  
Advera Ngaiza ◽  
Aveline Kahinga ◽  
Faustine Bukanu

Sinus histiocytosis with massive lymphadenopathy (Rosai–Dorfman disease) being a rare benign proliferative self-limiting disease of the cells of macrophage-histiocyte family is of unknown etiology and presents with massive lymphadenopathy. We are hereby reporting a case of RDD presenting with massive bilateral cervical and submandibular lymphadenopathy, diagnosed by histocytopathology.


2018 ◽  
Vol 10 (04) ◽  
pp. 460-463
Author(s):  
Manjari Kishore ◽  
Prajwala Gupta ◽  
Arvind Ahuja ◽  
Minakshi Bhardwaj

ABSTRACTRosai–Dorfman disease (RDD) or sinus histiocytosis with massive lymphadenopathy (SHML) is a self-limiting, benign histiocytic disorder. We report a case of RDD mimicking lymphoma clinically and cytologically in a 3-year-old male child. The present case highlights the importance of cytology in the diagnosis of RDD along with cytological features of other differential diagnoses.


2008 ◽  
Vol 13 (4) ◽  
pp. 806-809 ◽  
Author(s):  
Sean P. Zivin ◽  
Mohammed Atieh ◽  
Michael Mosier ◽  
Gladell P. Paner ◽  
Gerard V. Aranha

Author(s):  
Uppin Narayan Reddy ◽  
Swathi Chacham ◽  
Janampally Ravikiran ◽  
Jillalla Narsing Rao ◽  
Jakkampudi Nagasravani ◽  
...  

2018 ◽  
Vol 17 (4) ◽  
pp. 452 ◽  
Author(s):  
Rubyath C. Rajib ◽  
Rajasekharan Pillai ◽  
Ibrahim A. Sulaiman ◽  
Ibrahim Al-Haddabi

Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions.


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