Soft Tissue Rosai-Dorfman Disease: Case report

Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions.

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Soft tissue Rosai-Dorfman disease of the posterior mediastinum

Jornal Brasileiro de Pneumologia ◽

10.1590/s1806-37132009000700015 ◽

2009 ◽

Vol 35 (7) ◽

pp. 717-720 ◽

Cited By ~ 8

Author(s):

Antônio Luiz Penna Costa ◽

Natália Oliveira e Silva ◽

Marina Pamponet Motta ◽

Rodrigo Abensur Athanazio ◽

Daniel Abensur Athanazio ◽

...

Keyword(s):

Soft Tissue ◽

Surgical Excision ◽

Posterior Mediastinum ◽

Extranodal Involvement ◽

Surgical Specimen ◽

Massive Lymphadenopathy ◽

Rosai Dorfman Disease ◽

History Of ◽

Paravertebral Mass

Rosai-Dorfman disease (RDD) consists of sinus histiocytosis with massive lymphadenopathy. Extranodal involvement occurs in up to 43% of cases. However, isolated soft tissue RDD is rare. Isolated mediastinal RDD is exceedingly rare, and there have been only three previous reports. Involvement of the posterior mediastinum in RDD has been reported only in the context of disseminated RDD. Here, we report the case of a 49-year-old female patient with a two-year history of cervical pain and lymphadenomegaly, which resolved spontaneously. A CT scan revealed a left paravertebral mass with a diameter of 6 cm. The patient was submitted to surgical excision of the mass. Microscopic examination and immunophenotyping of the surgical specimen led to a diagnosis of RDD. During a 12-month follow-up period, the patient complained of mild cough and chest pain. Periodic imaging tests showed no sign of recurrence, and no postoperative cervical lymphadenomegaly was detected.

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Intralesional steroid induced hypopigmentation- a case report

International Journal of Scientific Reports ◽

10.18203/issn.2454-2156.intjscirep20171475 ◽

2017 ◽

Vol 3 (4) ◽

pp. 108

Author(s):

Shailendra Vikram Jitendra Singh ◽

Romita Bachaspatimayum ◽

Subhalakshmi Devi Akham ◽

Rita Devi Sanjenbam

Keyword(s):

Case Report ◽

Adverse Effects ◽

Male Patient ◽

Steroid Therapy ◽

Surgical Excision ◽

Treatment Modalities ◽

Benign Condition ◽

Left Wrist ◽

Intralesional Steroid

Ganglions are tense, smooth, fluctuant, cystic transilluminant swellings commonly found on the dorsum of the wrist, at the scapholunate articulation. Treatment modalities include aspiration, intralesional corticosteroids, surgical excision, etc. Hypopigmentation is one of the adverse effects associated with intralesional steroid therapy. Here, we report a 21 years old male patient who came with an asymptomatic whitish patch on the left wrist after receiving triaminolone 40 mg injection at the same site for a ganglion.Case is being reported so as to create awareness of this benign condition amongst the treating physicians or surgeons.

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Extranodal rosai dorfman disease: a case report of single soft tissue cystic lesion

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20202288 ◽

2020 ◽

Vol 8 (6) ◽

pp. 2329

Author(s):

Ruchi Agrawal ◽

Anurag Saha ◽

Bhanita Baro

Keyword(s):

Case Report ◽

Soft Tissue ◽

Male Patient ◽

Cystic Lesion ◽

Left Forearm ◽

Rosai Dorfman Disease

Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. It is found worldwide and slightly more common among in men (1.4:1), affecting individuals are with an average age of 20.6 years. Extranodal tissue involvement is documented in 25-43% of RDD patients. Here authors are discussing a case of 16-year-old male patient with the complaint of a single swelling over left forearm since one month with no lymphadenopathy. Radiology showed anechoic collection within the muscle and superficial to it. On microscopy, smear showed diffusely distributed histiocytes with cytoplasm showing intact lymphocytes with halo surrounding it (emperipolesis), without atypia. Based on cytomorphology diagnosis of Extranodal Rosai Dorfman Disease was made.

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HISTOCYTOPATHOLOGICAL DIAGNOSIS OF ROSAI-DORFMAN DISEASE: CASE REPORT AND LITERATURE REVIEW

10.22541/au.162754078.89271454/v1 ◽

2021 ◽

Author(s):

Zephania Abraham ◽

Zerd Francis ◽

Advera Ngaiza ◽

Aveline Kahinga ◽

Faustine Bukanu

Keyword(s):

Case Report ◽

Literature Review ◽

Sinus Histiocytosis ◽

Unknown Etiology ◽

Massive Lymphadenopathy ◽

Rosai Dorfman Disease ◽

Disease Case

Sinus histiocytosis with massive lymphadenopathy (Rosai–Dorfman disease) being a rare benign proliferative self-limiting disease of the cells of macrophage-histiocyte family is of unknown etiology and presents with massive lymphadenopathy. We are hereby reporting a case of RDD presenting with massive bilateral cervical and submandibular lymphadenopathy, diagnosed by histocytopathology.

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SOFT TISSUE ROSAI: DORFMAN DISEASE OF THE SACRAL REGION, A VERY RARE DISEASE: CASE REPORT AND REVIEW OF LITERATURE

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2014/3749 ◽

2014 ◽

Vol 3 (58) ◽

pp. 13152-13154

Author(s):

Jomine Jose ◽

Vergis Paul ◽

Najeeb Mohammad

Keyword(s):

Case Report ◽

Soft Tissue ◽

Rare Disease ◽

Review Of Literature ◽

Sacral Region ◽

Rosai Dorfman Disease ◽

Disease Case

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Prosthodontic approach to manage maxillary flabby ridge and severely resorbed mandibular residual ridge – a case report

Clinical Dentistry ◽

10.33882/clinicaldent.13.24349 ◽

2019 ◽

pp. 30-34

Author(s):

Asish Kumar Barui ◽

Abhisek Chowdhury ◽

T. K. Giri ◽

S Mukharjee

Keyword(s):

Case Report ◽

Soft Tissue ◽

Surgical Excision ◽

Treatment Modalities ◽

Surgical Removal ◽

Neutral Zone ◽

Alveolar Ridge ◽

Ridge Augmentation ◽

Impression Technique ◽

Clinical Conditions

Brief Background Fabrication of any dental prosthesis over a compromised residual alveolar ridge is really a challenge for prosthodontists. Fibrous or flabby ridge and highly resorbed residual alveolar ridge are two clinical situations that require special considerations during construction of any prosthesis. Mobile soft tissue and flattened alveolar ridge significantly compromise denture stability and support. There are different treatment modalities to manage these clinical conditions like surgical excision of soft tissue, ridge augmentation, modification in impression technique, etc. Materials and Methods This case report is about an old completely edentulous male patient who reported with a complaint of difficulty in chewing with his present denture. Discussion Prosthodontic management of a patient with compromised residual alveolar ridges needs special consideration . Selection of treatment modality depends on patients general health ,clinical condition of residual alveolar ridges , financial capacity and skill of the clinician A modification from conventional impression procedure was used to record maxillary flabby anterior ridge and neutral zone concept was applied for teeth arrangement to improve denture stability in atrophied lower alveolar ridge. Summary and Conclusions Surgical removal of soft tissue and implant supported prosthesis may not be possible in all situations. In that case a conservative approach using modified impression technique, neutral zone concept provides the basic triad of a successful denture prosthesis that is retention, stability and support. Key Words Flabby tissue, Window technique, Resorbed ridge, Neutral zone.

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Rosai Dorfman disease: a case report

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20180730 ◽

2018 ◽

Vol 4 (2) ◽

pp. 582

Author(s):

Yazid Bin Pol Ong ◽

Loong Siow Ping ◽

Khor Foo Kiang ◽

Gan Soon Ching ◽

Angeline Bt Madatang ◽

...

Keyword(s):

Case Report ◽

Soft Tissue ◽

Fine Needle Aspiration ◽

Needle Aspiration ◽

Granulomatous Disease ◽

Soft Tissue Density ◽

Fine Needle ◽

Massive Lymphadenopathy ◽

Rosai Dorfman Disease ◽

Benign Course

Rosai Dorfman disease (RDD) is a rare granulomatous disease that typically presents with massive lymphadenopathy. To our knowledge, there have only been 650 cases reported worldwide. It is more common among adults and has characteristic clinical, radiological and histopathological findings. Here, we present a case of RDD in a 51 year-old man with massive submental lymphadenopathy which was not responding to antibiotics. Computerized Tomographic Scan showed ill-defined non-enhancing soft tissue density while fine needle aspiration for cytology displayed emperipolesis which is seen in patients with RDD. The swelling followed a benign course and reduced in size progressively without further intervention.

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