Anti-cytokeratin CAM 5.2 does not act as a surrogate of the cytokeratin 8/18 monoclonal antibody. Comment on: “Utility of p63 in the differential diagnosis of atypical fibroxanthoma and spindle cell squamous cell carcinoma”, in J Cutan Pathol 2009; 36: 54

2010 ◽  
Vol 37 (10) ◽  
pp. 1123-1124 ◽  
Author(s):  
Jih-Tseng Chen ◽  
Jeng-Dong Hsu ◽  
Chung-Chin Yao ◽  
Lih-Wen Han ◽  
Chih-Ping Han
Keyword(s):  
Monoclonal Antibody ◽  
Squamous Cell Carcinoma ◽  
Differential Diagnosis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Cutan Pathol ◽  
Atypical Fibroxanthoma

Utility of p63 in the differential diagnosis of atypical fibroxanthoma and spindle cell squamous cell carcinoma

2009 ◽  
Vol 36 (5) ◽  
pp. 543-547 ◽  
Author(s):  
Briana C. Gleason ◽  
Kenneth B. Calder ◽  
Thomas L. Cibull ◽  
Antoinette B. Thomas ◽  
Steven D. Billings ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Differential Diagnosis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Atypical Fibroxanthoma

Squamous Cell Carcinoma Detected by High-Molecular-Weight Cytokeratin Immunostaining Mimicking Atypical Fibroxanthoma

2001 ◽  
Vol 125 (6) ◽  
pp. 799-802 ◽  
Author(s):  
Yulia Gray ◽  
Henry J. Robidoux ◽  
David S. Farrell ◽  
Leslie Robinson-Bostom
Keyword(s):  
Molecular Weight ◽  
Squamous Cell Carcinoma ◽  
Chronic Lymphocytic Leukemia ◽  
Cell Carcinoma ◽  
High Molecular Weight ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Lymphocytic Leukemia ◽  
Atypical Fibroxanthoma ◽  
Desmoplastic Melanoma

Abstract Atypical fibroxanthoma can mimic other tumors, particularly spindle cell squamous cell carcinoma and spindle cell or desmoplastic melanoma. We describe a patient with chronic lymphocytic leukemia who developed acantholytic squamous cell carcinoma on the face, which recurred and metastasized to a cervical lymph node. This tumor was at first diagnosed as atypical fibroxanthoma because of its histologic and immunostaining similarity. It showed weak or negative keratin cocktail staining and strong vimentin staining. However, a recurrent tumor was immunostained for high-molecular-weight keratin and showed strong positivity. Aggressive behavior of this squamous cell carcinoma may be due to altered immune response secondary to chronic lymphocytic leukemia.

Spindle Cell Carcinoma of the Tongue: Fallacies in Its Diagnosis

2018 ◽  
Vol 3 (02) ◽  
Author(s):  
Amrit Kaur Kaler, Shweta C, Smitha Chandra B.C, Rajeev Naik
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Cell Population ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Biphasic Tumor ◽  
Carcinoma Of The Tongue ◽  
Ihc Markers

Spindle cell carcinoma is a rare aggressive biphasic tumor, composed of neoplastic proliferation of both epithelial (squamous) and spindle cell population. It constitutes about 1% of all oral cavity tumors 2a and is almost rare on the tongue; only few cases have been reported so far. This variant of squamous cell carcinoma, comprises major diagnostic problems due to its varied histomorphology and resemblance to sarcomatous lesion; hence diligent screening and IHC markers are mandatory for its diagnosis.

Clinicopathologic features and outcome of head and neck mucosal spindle cell squamous cell carcinoma

2021 ◽  
Author(s):  
Carlos N. Prieto-Granada ◽  
Bin Xu ◽  
Bayan Alzumaili ◽  
Mohamed Rizwan Haroon Al Rasheed ◽  
Antoine Eskander ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Clinicopathologic Features
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