A phase I clinical trial of the histone deacetylase inhibitor belinostat in patients with advanced hematological neoplasia

European Journal Of Haematology ◽

10.1111/j.1600-0609.2008.01102.x ◽

2008 ◽

Vol 81 (3) ◽

pp. 170-176 ◽

Author(s):

Peter Gimsing ◽

Mads Hansen ◽

Lene M. Knudsen ◽

P. Knoblauch ◽

Ib Jarle Christensen ◽

...

Keyword(s):

Clinical Trial ◽

Phase I ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Clinical Trial ◽

Deacetylase Inhibitor

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Evaluation of safety, pharmacokinetics, and efficacy of vorinostat, a histone deacetylase inhibitor, in the treatment of gastrointestinal (GI) cancer in a phase I clinical trial

International Journal of Clinical Oncology ◽

10.1007/s10147-011-0348-6 ◽

2012 ◽

Vol 18 (1) ◽

pp. 87-95 ◽

Author(s):

Toshihiko Doi ◽

Tetsuya Hamaguchi ◽

Kuniaki Shirao ◽

Kensho Chin ◽

Kiyohiko Hatake ◽

...

Keyword(s):

Clinical Trial ◽

Phase I ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Clinical Trial ◽

Gi Cancer ◽

Deacetylase Inhibitor

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A phase I clinical trial of an oral formulation of the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA)

European Journal of Cancer ◽

10.1016/s0959-8049(02)80937-6 ◽

2002 ◽

Vol 38 ◽

pp. S88 ◽

Keyword(s):

Clinical Trial ◽

Phase I ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Oral Formulation ◽

Phase I Clinical Trial ◽

Suberoylanilide Hydroxamic Acid ◽

Deacetylase Inhibitor

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Combination of the histone deacetylase inhibitor vorinostat with bevacizumab in patients with clear-cell renal cell carcinoma: a multicentre, single-arm phase I/II clinical trial

British Journal of Cancer ◽

10.1038/bjc.2017.33 ◽

2017 ◽

Vol 116 (7) ◽

pp. 874-883 ◽

Author(s):

Roberto Pili ◽

Glenn Liu ◽

Sreenivasulu Chintala ◽

Hendrick Verheul ◽

Shabnam Rehman ◽

...

Keyword(s):

Clinical Trial ◽

Renal Cell Carcinoma ◽

Phase I ◽

Cell Carcinoma ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Cell Renal Cell Carcinoma ◽

Deacetylase Inhibitor

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Potentiation of a Topoisomerase I Inhibitor, Karenitecin, by the Histone Deacetylase Inhibitor Valproic Acid in Melanoma: Translational and Phase I/II Clinical Trial

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-08-1931 ◽

2009 ◽

Vol 15 (7) ◽

pp. 2479-2487 ◽

Author(s):

Adil I. Daud ◽

Jana Dawson ◽

Ronald C. DeConti ◽

Elona Bicaku ◽

Douglas Marchion ◽

...

Keyword(s):

Clinical Trial ◽

Valproic Acid ◽

Phase I ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Topoisomerase I ◽

Topoisomerase I Inhibitor ◽

Deacetylase Inhibitor

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Effects of the histone deacetylase inhibitor (HDACI) LAQ824 on histone acetylation, Hsp70 and c-Raf in peripheral blood lymphocytes from patients with advanced solid tumours enrolled in a phase I clinical trial

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.90140.3023 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3023-3023

Author(s):

R. S. Kristeleit ◽

D. Tandy ◽

P. Atadja ◽

A. Patnaik ◽

J. Scott ◽

...

Keyword(s):

Clinical Trial ◽

Phase I ◽

Histone Acetylation ◽

Histone Deacetylase ◽

Peripheral Blood ◽

Histone Deacetylase Inhibitor ◽

Peripheral Blood Lymphocytes ◽

Solid Tumours ◽

Blood Lymphocytes ◽

Deacetylase Inhibitor

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Effects of the histone deacetylase inhibitor (HDACI) LAQ824 on histone acetylation, Hsp70 and c-Raf in peripheral blood lymphocytes from patients with advanced solid tumours enrolled in a phase I clinical trial

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.14_suppl.3023 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3023-3023 ◽

Author(s):

R. S. Kristeleit ◽

D. Tandy ◽

P. Atadja ◽

A. Patnaik ◽

J. Scott ◽

...

Keyword(s):

Clinical Trial ◽

Phase I ◽

Histone Acetylation ◽

Histone Deacetylase ◽

Peripheral Blood ◽

Histone Deacetylase Inhibitor ◽

Peripheral Blood Lymphocytes ◽

Solid Tumours ◽

Blood Lymphocytes ◽

Deacetylase Inhibitor

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Faculty of 1000 evaluation for A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.718050520.793482822 ◽

2013 ◽

Author(s):

Burton Eisenberg

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Pediatric Patients ◽

Deacetylase Inhibitor

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A Phase I Study of Quisinostat (JNJ-26481585), an Oral Hydroxamate Histone Deacetylase Inhibitor with Evidence of Target Modulation and Antitumor Activity, in Patients with Advanced Solid Tumors

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-13-0312 ◽

2013 ◽

Vol 19 (15) ◽

pp. 4262-4272 ◽

Author(s):

Balaji Venugopal ◽

Richard Baird ◽

Rebecca S. Kristeleit ◽

Ruth Plummer ◽

Richard Cowan ◽

...

Keyword(s):

Antitumor Activity ◽

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Advanced Solid Tumors ◽

Deacetylase Inhibitor

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A phase I–II study of the histone deacetylase inhibitor valproic acid plus chemoimmunotherapy in patients with advanced melanoma

British Journal of Cancer ◽

10.1038/sj.bjc.6604817 ◽

2009 ◽

Vol 100 (1) ◽

pp. 28-36 ◽

Author(s):

A Rocca ◽

S Minucci ◽

G Tosti ◽

D Croci ◽

F Contegno ◽

...

Keyword(s):

Valproic Acid ◽

Phase I ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Advanced Melanoma ◽

Deacetylase Inhibitor

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A phase I and pharmacodynamic study of the histone deacetylase inhibitor belinostat plus azacitidine in advanced myeloid neoplasia

Investigational New Drugs ◽

10.1007/s10637-014-0194-2 ◽

2014 ◽

Vol 33 (2) ◽

pp. 371-379 ◽

Author(s):

Olatoyosi Odenike ◽

Anna Halpern ◽

Lucy A. Godley ◽

Jozef Madzo ◽

Theodore Karrison ◽

...

Keyword(s):

Phase I ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Deacetylase Inhibitor ◽

Pharmacodynamic Study ◽

Myeloid Neoplasia

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