Structure, Organization, and Controlled Expression of the Genes Coding for the Variable and Constant Regions of Mouse Immunoglobulin Light Chains

1977 ◽  
Vol 36 (1) ◽  
pp. 3-28 ◽  
Author(s):  
Israel Schechter ◽  
Yigal Burstein ◽  
Ronald Zemell
1973 ◽  
Vol 80 (3) ◽  
pp. 553-557 ◽  
Author(s):  
M. Smith ◽  
J. Stavnezer ◽  
R.C. Huang ◽  
J.B. Gurdon ◽  
C.D. Lane

1976 ◽  
Vol 144 (1) ◽  
pp. 298-303 ◽  
Author(s):  
D Gibson

Light chains isolated from normal immunoglobulin of unimmunized mice were analyzed by gel isoelectric focusing. Examination of the focusing patterns of light chains from nine inbred mouse strains showed that six of the strains (SWR/J, C3H/HeJ, DBA/1J, A/J, CBA/J, and C57BL/6J) possessed a virtually identical spectrum of focusing bands, while the remaining three strains (RF/J, AKR/J, and C58/J) showed clear differences involving several bands. Analysis of the light chains of individual SWR/J, C58/J, and F1 hybrid mice indicated that the differences in focusing pattern were inherited in a simple codominant fashion. A new procedure was developed for the rapid analysis of light chains from small quantities of serum.


1974 ◽  
Vol 140 (5) ◽  
pp. 1432-1437 ◽  
Author(s):  
Paul D. Gottlieb

The inbred and congenic strain distribution of the IH-peptide marker in the variable region of mouse immunoglobulin light chains has been compared with other known genetic markers. A positive correlation was noted between the IH-peptide marker and expression of the Ly-3.1 thymocyte cell surface antigen. This suggests that the locus responsible for IH-peptide expression is genetically linked to the Ly-2 and Ly-3 loci in linkage group XI on chromsome 6 of the mouse.


1993 ◽  
Vol 23 (8) ◽  
pp. 1980-1986 ◽  
Author(s):  
Sue E. Stewart ◽  
Louis Du Pasquier ◽  
Lisa A. Steiner

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