In Vivo Absorption of Theophylline and Salicylic Acid from Rat Small Intestine

2009 ◽  
Vol 55 (5) ◽  
pp. 335-338 ◽  
Author(s):  
Ö. Johansson ◽  
T. Lindberg ◽  
A. Melander
Keyword(s):  
Small Intestine ◽  
Salicylic Acid ◽  
Rat Small Intestine ◽  
In Vivo Absorption

Absorption of homocitrulline from the gastrointestinal tract

1983 ◽  
Vol 49 (1) ◽  
pp. 35-42 ◽  
Author(s):  
D. F. Evered ◽  
J. V. Vadgama
Keyword(s):  
Small Intestine ◽  
Metabolic Inhibitors ◽  
Rat Small Intestine ◽  
Carrier System ◽  
Milk Products ◽  
Buccal Absorption ◽  
Saturation Kinetics ◽  
In Vivo Absorption

1. Transport ofL-homocitrulline, an amino acid which occurs in milk products, was studied with rat small intestine in vitro and from the human mouth in vivo. Absorption was partially dependent, in both systems, on the presence of sodium ions.2. Metabolic inhibitors decreasedL-homocitrulline uptake across the small intestine. Transport across the intestine did not occur against the concentration gradient but did show saturation kinetics.3. The barbiturate, amytal, did not inhibit buccal absorption. Saturation kinetics were demonstrated.4. Experiments were conducted withL-citrulline, or other amino acids, as possible inhibitors ofL-homocitrulline transport. Results were compatible with Na+-dependent carrier-mediated uptake across the buccal mucosa. Active transport could be involved with the small intestine assuming thatL-homocitrulline has a low affinity for the carrier system.

scholarly journals Absorption of lactulose from mammalian gastrointestinal tract

1979 ◽  
Vol 41 (1) ◽  
pp. 47-51 ◽  
Author(s):  
D. F. Evered ◽  
F. Sadoogh-Abasian
Keyword(s):  
Small Intestine ◽  
Calcium Ions ◽  
Clinical Evidence ◽  
Buccal Cavity ◽  
Rat Small Intestine ◽  
Sodium Ions ◽  
Mode Of Transport ◽  
Poor Absorption

1. The disaccharide lactulose (galactosyl-β-1,4-fructose) was poorly absorbed from rat small intestine in vitro and human mouth in vivo.2. These results confirm indirect clinical evidence of poor absorption from the intestine.3. The presence of calcium ions, or absence of sodium ions, had no effect on lactulose absorption from the buccal cavity.4. The presence of ouabain, or absence of Na+, did not decrease the absorption of lactulose from small intestine.5. It is thought that the mode of transport, in both instances, is by passive diffusion with the concentration gradient.

The Influence of Pregnancy and Lactation on the Morphology and Absorptive Capacity of the Rat Small Intestine

1970 ◽  
Vol 38 (3) ◽  
pp. 287-295 ◽  
Author(s):  
I. L. Craft
Keyword(s):  
Small Intestine ◽  
Surface Area ◽  
Absorptive Capacity ◽  
Dry Weight ◽  
Total Weight ◽  
Rat Small Intestine ◽  
Pregnancy And Lactation ◽  
In Pregnancy

1. A study of the length, total weight and weight per cm of the small intestine of virgin, pregnant and lactating rats has provided evidence for an increase in intestinal surface area in pregnancy and lactation. 2. Because of such alterations in morphology of the gut the absorption,in vivo, of the substrates studied, glucose and glycine, has been expressed in terms of amount transferred per loop and also per g dry weight of intestine. 3. Using these parameters the results show that pregnancy does not alter the ability of the upper jejunum to absorb glucose and glycine. In lactation there is a significant decrease in the transfer of these substances when expressed per g dry weight of intestine, but not in absolute terms.

scholarly journals Absorption of two proline containing peptides by rat small intestine in vivo.

1975 ◽  
Vol 248 (1) ◽  
pp. 143-149 ◽  
Author(s):  
A E Lane ◽  
D B Silk ◽  
M L Clark
Keyword(s):  
Small Intestine ◽  
Rat Small Intestine
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