Mineral trioxide aggregate as a root canal filling material in reimplanted teeth. Microscopic analysis in monkeys

Mineral trioxide aggregate (MTA) is widely used in various dental endodontic applications such as root-end filling, furcal perforation repair, and vital pulp therapy. In spite of many attempts to improve handling properties and reduce the discoloration of MTA, the ideal root canal filling material has yet to be fully developed. The objective of this study was to investigate the setting time, mechanical properties, and biocompatibility of MTA set by a silk fibroin solution. A 5 wt% silk fibroin (SF) solution (a novel hydration accelerant) was used to set SavDen® MTA and ProRoot® white MTA (WMTA). Changes in setting time, diametral tensile strength (DTS), material crystallization, in vitro cell viability, and cell morphology were assessed by Vicat needle measurement, a universal testing machine, scanning electron microscopy (SEM), and WST-1 assay, respectively. The initial setting time of ProRoot® MTA and SavDen® MTA experienced a drastic decrease of 83.9% and 42.1% when deionized water was replaced by 5 wt% SF solution as the liquid phase. The DTS of SavDen® MTA showed a significant increase after set by the SF solution in 24 h. A human osteoblast-like cell (MG-63)-based WST-1 assay revealed that both ProRoot® MTA and SavDen® MTA hydrated using SF solution did not significantly differ (p > 0.05) in cell viability. MG-63 cells with pseudopodia attachments and nuclear protrusions represent a healthier and more adherent status on the surface of MTA when set with SF solution. The results suggest that the 5 wt% SF solution may be used as an alternative hydration accelerant for MTA in endodontic applications.

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A Novel Sol-Gel Bi2-xHfxO3+x/2 Radiopacifier for Mineral Trioxide Aggregates (MTA) as Dental Filling Materials

Applied Sciences ◽

10.3390/app11167292 ◽

2021 ◽

Vol 11 (16) ◽

pp. 7292

Author(s):

Tzu-Sen Yang ◽

May-Show Chen ◽

Cheng-Jyun Huang ◽

Chin-Yi Chen ◽

Agnese Brangule ◽

...

Keyword(s):

Electron Microscopy ◽

Cell Viability ◽

Root Canal ◽

Sol Gel ◽

Mineral Trioxide Aggregate ◽

Filling Material ◽

Root Canal Filling ◽

Calcination Temperatures ◽

Filling Materials

Mineral trioxide aggregate (MTA) is well known as an effective root canal filling material for endodontics therapy. Within MTA, bismuth oxide (Bi2O3) serving as the radiopacifier still has biocompatibility concerns due to its mild cytotoxicity. In the present study, we tried to modify the Bi2O3 radiopacifier by doping hafnium ions via the sol-gel process and investigated the effects of different doping ratios (Bi2-xHfxO3+x/2, x = 0–0.3) and calcination temperatures (400–800 °C). We mixed various precursor mixtures of bismuth nitrate (Bi(NO3)3·5H2O) and hafnium sulfate (Hf(SO4)2) and controlled the calcination temperatures. The as-prepared Hf-doped Bi2O3 radiopacifier powders were investigated by thermogravimetric analysis (TGA), X-ray diffraction (XRD), field-emission scanning electron microscopy (FESEM), and transmission electron microscopy (TEM). Portland cement/radiopacifier/calcium sulfate (75/20/5) were mixed and set by deionized water (powder to water ratio = 3:1). Changes in radiopacity, diametral tensile strength (DTS), and in vitro cell viability of the hydrated MTA-like cement were carried out. The experimental results showed that the group containing radiopacifier from sol-gelled Bi/Hf (90/10) exhibited significantly higher radiopacity (6.36 ± 0.34 mmAl), DTS (2.54 ± 0.29 MPa), and cell viability (84.0±8.1%) (p < 0.05) when compared to that of Bi/Hf (100/0) powders. It is suggested that the formation of β-Bi7.78Hf0.22O12.11 phase with hafnium addition and calcining at 700 °C can prepare novel bismuth/hafnium composite powder that can be used as an alternative radiopacifier for root canal filling materials.

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Mineral trioxide aggregate (MTA) as an alternative root canal filling material

http://isrctn.com/ ◽

10.1186/isrctn15285974 ◽

2015 ◽

Author(s):

Reem Alsulaimani

Keyword(s):

Root Canal ◽

Mineral Trioxide Aggregate ◽

Filling Material ◽

Root Canal Filling

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23. An Experimental Study on AH-26, Root Canal Filling Material with EPOXY-RESIN Basis (4th report)

The Journal of the Kyushu Dental Society ◽

10.2504/kds.21.192 ◽

1967 ◽

Vol 21 (3) ◽

pp. 192-193

Author(s):

M. Yoshida

Keyword(s):

Experimental Study ◽

Epoxy Resin ◽

Root Canal ◽

Filling Material ◽

Root Canal Filling

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Radicular Perforation Repair with Mineral Trioxide Aggregate: A Case Report with 10-Year Follow-up

The Open Dentistry Journal ◽

10.2174/1874210601610010733 ◽

2016 ◽

Vol 10 (1) ◽

pp. 733-738 ◽

Cited By ~ 3

Author(s):

Leopoldo Cosme-Silva ◽

Breno Carnevalli ◽

Vivien Thiemy Sakai ◽

Naiana Viana Viola ◽

Leon Franco de Carvalho ◽

...

Keyword(s):

Case Report ◽

Root Canal ◽

Mineral Trioxide Aggregate ◽

Radiographic Examination ◽

Root Canal Filling ◽

Second Molar ◽

Iatrogenic Perforation ◽

Iatrogenic Complications ◽

Root Canal Retreatment

Background: Iatrogenic complications such as accidental perforation of the root or the floor of the pulp chamber may occur. Case Report: Patient was referred for root canal retreatment of the mandibular left second molar with periapical lesion evidenced through radiographic examination. During post removal, iatrogenic perforation occurred at the mesial face of the distal root. After clinical localization of the perforation and bleeding control, MTA was applied. In a second appointment, the root canal filling was removed and the chemical-surgical retreatment of the canals was performed, followed by the obturation with gutta-percha and sealer. Patient returned after three days reporting no pain. After 6 months, 3, 7 and 10 years of follow-up. Conclusion: Absence of pain, normal periodontal probing and lack of radiolucent area at the region of perforation and the periapices were detected, which evidenced the successful repair of the tooth.

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