Increased Plasma and Erythrocyte Selenium Concentrations but Decreased Erythrocyte Glutathione Peroxidase Activity after Selenium Supplementation in Children with Down Syndrome

1989 ◽  
Vol 78 (6) ◽  
pp. 879-884 ◽  
Author(s):  
G. ANNEREN ◽  
M. GEBRE-MEDHIN ◽  
K.-H. GUSTAVSON
2019 ◽  
Vol 42 (1) ◽  
pp. 1-8 ◽  
Author(s):  
José Araújo de Oliveira-Silva ◽  
Joyce Umbelino Pinto Yamamoto ◽  
Renata Bernardes de Oliveira ◽  
Vaneisse Cristina Lima Monteiro ◽  
Beatriz Jurkiewcz Frangipani ◽  
...  

1985 ◽  
Vol 63 (7) ◽  
pp. 1544-1547 ◽  
Author(s):  
Charles T. Robbins ◽  
Steven M. Parish ◽  
Barbara L. Robbins

Blood glutathione peroxidase (GSH-Px) activity in mountain goats (Oreamnos americanus) is a linear function of blood selenium. GSH-Px activity per unit of selenium (Se) in mountain goats is approximately double that published for the domestic cow and horse. It is hypothesized that high GSH-Px activity per unit selenium in mountain goats reduces their dietary selenium requirement relative to the above domestic species and is an essential adaptation for occupying low-selenium environments. GSH-Px activity peaked 20–30 days after injections of 0.1 and 0.3 mg Se/kg. A higher dose of 0.5 mg Se/kg delayed and decreased the development of peak GSH-Px activity relative to the two lower injection groups. When acute pathology owing to a selenium deficiency is demonstrated in wildlife capture programs, passive selenium supplementation, such as with selenium-containing salt blocks, should begin weeks to months before capture to provide adequate time for GSH-Px development.


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