The ‘phloem necrosis’ virus disease of tea in Ceylon II. Field observations and effect on yield

Abstract A new distribution map is provided for Elm phloem necrosis virus. Hosts: Elm (Ulmus spp.). Information is given on the geographical distribution in NORTH AMERICA, USA.

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Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential

Open Biology ◽

10.1098/rsob.200237 ◽

2020 ◽

Vol 10 (11) ◽

pp. 200237 ◽

Cited By ~ 1

Author(s):

Johannes Gregor Matthias Rack ◽

Valentina Zorzini ◽

Zihan Zhu ◽

Marion Schuller ◽

Dragana Ahel ◽

...

Keyword(s):

Virus Disease ◽

Cross Reactivity ◽

Structural Basis ◽

Evolutionary Analysis ◽

Structural Studies ◽

Post Translational Modification ◽

Necrosis Virus ◽

Adp Ribosylation ◽

Pharmacological Potential ◽

And Function

Viral macrodomains possess the ability to counteract host ADP-ribosylation, a post-translational modification implicated in the creation of an antiviral environment via immune response regulation. This brought them into focus as promising therapeutic targets, albeit the close homology to some of the human macrodomains raised concerns regarding potential cross-reactivity and adverse effects for the host. Here, we evaluate the structure and function of the macrodomain of SARS-CoV-2, the causative agent of COVID-19. We show that it can antagonize ADP-ribosylation by PARP14, a cellular (ADP-ribosyl)transferase necessary for the restriction of coronaviral infections. Furthermore, our structural studies together with ligand modelling revealed the structural basis for poly(ADP-ribose) binding and hydrolysis, an emerging new aspect of viral macrodomain biology. These new insights were used in an extensive evolutionary analysis aimed at evaluating the druggability of viral macrodomains not only from the Coronaviridae but also Togaviridae and Iridoviridae genera (causing diseases such as Chikungunya and infectious spleen and kidney necrosis virus disease, respectively). We found that they contain conserved features, distinct from their human counterparts, which may be exploited during drug design.

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First report on development of sustainable management strategy against Pentalonia nigronervosa coq. vector of banana bunchy top virus disease, its seasonal variation and effect on yield of banana in Jorhat district of Assam– A north eastern state of India

Journal of Entomology and Zoology Studies ◽

10.22271/j.ento.2019.v7.i2.2.07 ◽

2019 ◽

Vol 7 (2.2) ◽

pp. 158-167

Author(s):

Nilakshi Kakati ◽

PD Nath

Keyword(s):

Seasonal Variation ◽

Sustainable Management ◽

Management Strategy ◽

Virus Disease ◽

Banana Bunchy Top Virus ◽

First Report ◽

Eastern State ◽

North Eastern ◽

Effect On Yield ◽

Pentalonia Nigronervosa

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Control of Infectious Hematopoietic Necrosis Virus Disease by Elevating the Water Temperature

Journal of the Fisheries Research Board of Canada ◽

10.1139/f70-034 ◽

1970 ◽

Vol 27 (2) ◽

pp. 265-270 ◽

Cited By ~ 44

Author(s):

Donald F. Amend

Keyword(s):

Elevated Temperature ◽

Water Temperature ◽

Sockeye Salmon ◽

Virus Disease ◽

Oncorhynchus Nerka ◽

Infectious Hematopoietic Necrosis Virus ◽

Temperature Treatment ◽

Necrosis Virus ◽

Infectious Hematopoietic Necrosis

Studies were performed to determine if increasing water temperatures could control infectious hematopoietic necrosis virus (IHN) disease in sockeye salmon (Oncorhynchus nerka). Mortalities could be prevented if the water temperature was raised to at least 18 C within the first 24 hr after infection of the fish and if the fish were maintained at this temperature for 4–6 days. The disease did not recur after the elevated temperature treatment, but the fish would still contract the disease if they were reinfected. Reasons for the protecting action are discussed.

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Weather based prediction models for thrips and bud necrosis virus disease in tomato

Indian Journal of Entomology ◽

10.5958/0974-8172.2020.00051.6 ◽

2020 ◽

Vol 82 (2) ◽

pp. 228

Author(s):

Timmanna ◽

Mohan I Naik ◽

A K Chakravarty ◽

R Ashokan ◽

V Sridhar

Keyword(s):

Prediction Models ◽

Virus Disease ◽

Necrosis Virus

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Identification of novel QTL contributing to barley yellow mosaic resistance in wild barley (Hordeum vulgare spp. spontaneum)

BMC Plant Biology ◽

10.1186/s12870-021-03321-x ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Yuhan Pan ◽

Juan Zhu ◽

Yi Hong ◽

Mengna Zhang ◽

Chao Lv ◽

...

Keyword(s):

Mosaic Virus ◽

Wild Barley ◽

Virus Disease ◽

Mosaic Disease ◽

Yellow Mosaic Virus ◽

New Genes ◽

Emerging Virus ◽

Mild Mosaic Virus ◽

Effect On Yield ◽

Virus Strains

Abstract Background Barley yellow mosaic disease (BYMD) caused by Barley yellow mosaic virus (BaYMV) and Barley mild mosaic virus (BaMMV) seriously threatens the production of winter barley. Cultivating and promoting varieties that carry disease-resistant genes is one of the most powerful ways to minimize the disease’s effect on yield. However, as the BYMD virus mutates rapidly, resistance conferred by the two cloned R genes to the virus had been overcome by new virus strains. There is an urgent need for novel resistance genes in barley that convey sustainable resistance to newly emerging virus strains causing BYMD. Results A doubled haploid (DH) population derived from a cross of SRY01 (BYMD resistant wild barley) and Gairdner (BYMD susceptible barley cultivar) was used to explore for QTL of resistance to BYMD in barley. A total of six quantitative trait loci (qRYM-1H, qRYM-2Ha, qRYM-2Hb, qRYM-3H, qRYM-5H, and qRYM-7H) related to BYMD resistance were detected, which were located on chromosomes 1H, 2H, 3H, 5H, and 7H. Both qRYM-1H and qRYM-2Ha were detected in all environments. qRYM-1H was found to be overlapped with rym7, a known R gene to the disease, whereas qRYM-2Ha is a novel QTL on chromosome 2H originated from SRY01, explaining phenotypic variation from 9.8 to 17.8%. The closely linked InDel markers for qRYM-2Ha were developed which could be used for marker-assisted selection in barley breeding. qRYM-2Hb and qRYM-3H were stable QTL for specific resistance to Yancheng and Yangzhou virus strains, respectively. qRYM-5H and qRYM-7H identified in Yangzhou were originated from Gairdner. Conclusions Our work is focusing on a virus disease (barley yellow mosaic) of barley. It is the first report on BYMD-resistant QTL from wild barley accessions. One novel major QTL (qRYM-2Ha) for the resistance was detected. The consistently detected new genes will potentially serve as novel sources for achieving pre-breeding barley materials with resistance to BYMD.

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