Calcitonin Gene-Related Peptide in the Brain, Spinal Cord, and Some Peripheral Systems

1992 ◽  
Vol 657 (1 Calcitonin Ge) ◽  
pp. 119-134 ◽  
Author(s):  
TOMAS HÖKFELT ◽  
ULF ARVIDSSON ◽  
SANDRA CECCATELLI ◽  
ROSER CORTÉS ◽  
STAFFAN CULLHEIM ◽  
...  
Clinics ◽  
2012 ◽  
Vol 67 (9) ◽  
pp. 1087-1091 ◽  
Author(s):  
PS do Nascimento ◽  
GA Lovatel ◽  
J Ilha ◽  
LL Xavier ◽  
BD Schaan ◽  
...  

1988 ◽  
Vol 50 (2) ◽  
pp. 480-485 ◽  
Author(s):  
Osamu Hiroshima ◽  
Yoshihisa Sano ◽  
Teruaki Yuzuriha ◽  
Chiyuki Yamato ◽  
Akira Saito ◽  
...  

1989 ◽  
Vol 3 (3) ◽  
pp. 247-252 ◽  
Author(s):  
S. J. Wimalawansa ◽  
H. R. Morris ◽  
I. Maclntyre

ABSTRACT The presence of both α- and β-calcitonin gene-related peptide (CGRP) was demonstrated by oxidation and by CNBr cleavage in extracts of plasma, cerebrospinal fluid and spinal cord in man. This was achieved by the use of both CNBr cleavage and oxidation of the methionine residue present in the human β-CGRP molecule. This study demonstrates that around 50% of CGRP immunoreactivity in plasma, cerebrospinal fluid and spinal cord is not α-CGRP, but corresponds to β-CGRP-like activity. Furthermore, experiments with CNBr also suggest the presence of another methionine-containing CGRP-like peptide in all three extracts.


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