Anti-inflammatory and platelet anti-aggregant activity of phospholipase-A2 inhibitors

1979 ◽  
Vol 31 (1) ◽  
pp. 588-592 ◽  
Author(s):  
E. VALLEE ◽  
J. GOUGAT ◽  
J. NAVARRO ◽  
J. F. DELAHAYES
Keyword(s):  
Phospholipase A2 ◽  
Anti Inflammatory ◽  
Phospholipase A2 Inhibitors

Phospholipase A2 Inhibitors as Potential Anti-Inflammatory Agents

2005 ◽  
Vol 11 (10) ◽  
pp. 1301-1312 ◽  
Author(s):  
M. Meyer ◽  
P. Rastogi ◽  
C. Beckett ◽  
J. McHowat
Keyword(s):  
Phospholipase A2 ◽  
Anti Inflammatory ◽  
Phospholipase A2 Inhibitors

Chemistry and Biology of Anti-Inflammatory Marine Natural Products. Phospholipase A2 Inhibitors

2005 ◽  
Vol 9 (14) ◽  
pp. 1419-1427 ◽  
Author(s):  
Luigi Gomez-Paloma ◽  
Maria Monti ◽  
Stefania Terracciano ◽  
Agostino Casapullo ◽  
Raffaele Riccio
Keyword(s):  
Natural Products ◽  
Phospholipase A2 ◽  
Marine Natural Products ◽  
Anti Inflammatory ◽  
Phospholipase A2 Inhibitors

Synthesis of Spongidine A, D and Petrosaspongiolide L Methyl Ester Using Pyridine C-H Functionalization

2019 ◽  
Author(s):  
Florian Bartels ◽  
Manuela Weber ◽  
Mathias Christmann
Keyword(s):  
Natural Products ◽  
Methyl Ester ◽  
Hydrogen Atom ◽  
Phospholipase A2 ◽  
Late Stage ◽  
Hydrogen Atom Transfer ◽  
Ring System ◽  
Tetracyclic Core ◽  
Intramolecular Hydrogen ◽  
Phospholipase A2 Inhibitors

<div>An efficient strategy for the synthesis of the potent phospholipase A2 inhibitors spongidine A and D is presented. The tetracyclic core of the natural products was assembled via an intramolecular hydrogen atom transfer‐initiated Minisci reaction. A divergent late‐stage functionalization of the tetracyclic ring system was also used to achieve a concise synthesis of petrosaspongiolide L methyl ester.</div>

A versatile synthon approach to the preparation of some phospholipase A2 inhibitors

1992 ◽  
Vol 33 (4) ◽  
pp. 547-550 ◽  
Author(s):  
JMC Golec ◽  
C.J.R. Hedgecock ◽  
P.D. Kennewell
Keyword(s):  
Phospholipase A2 ◽  
Phospholipase A2 Inhibitors

Synthesis of novel 2-pyrazoline analogues with potent anti-inflammatory effect mediated by inhibition of phospholipase A2: Crystallographic, in silico docking and QSAR analysis

2017 ◽  
Vol 27 (16) ◽  
pp. 3806-3811 ◽  
Author(s):  
Devirammanahalli Mahadevaswamy Lokeshwari ◽  
Dileep Kumar Achutha ◽  
Bharath Srinivasan ◽  
Naveen Shivalingegowda ◽  
Lokanath Neratur Krishnappagowda ◽  
...  
Keyword(s):  
Phospholipase A2 ◽  
In Silico ◽  
Qsar Analysis ◽  
In Silico Docking ◽  
Anti Inflammatory ◽  
Inflammatory Effect
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