Objectives: In reccent decades of research now link TWA with inducible and spontaneous clinical ventricular arrhythmias. This bench-tobedside foundation makes TWA a very plausible index of worsen of clinical status. Also with the heart rate variability. We research this study with 2 targets: 1. Prognosis value of TWA and HRV in heart failure. 2. Prognosis value of the combination of TWA and HRV in heart failure. Methods: Prospective study: 82 chronic heart failure patients were admitted to hospital from 2010 May to 2011 May and 50 healthy people were done treadmill test to caculate TWA, ECG, Holter ECG, echocardiography. Results: The combination of TWA and HRV to prognosic the worsen clinical status have the highest prognosis value with OR=102.13 (p<0.001) sensitivity: 80.49%, specificity: 98%, positive predict value: 98.51%, negative predict value: 75.38%. The combination of TWA and HRV to prognosic the ventricular arrythmia have the highest prognosis value with OR=46.25 (p<0.001) sensitivity: 83.33%, specificity: 90.24%, positive predict value: 89.74%, negative predict value: 84.09%. Conclusions: We should combine TWA and HRV in clinical to prognose heart failure patients.
Heart Rate Turbulence Is a Powerful Predictor of Cardiac Death and Ventricular Arrhythmias in Postmyocardial Infarction and Heart Failure Patients
