Characterization and virus susceptibility of a continuous cell line derived from the brain of Aequidens rivulatus (Günther)

2018 ◽  
Vol 41 (4) ◽  
pp. 635-641 ◽  
Author(s):  
S W Yeh ◽  
Y H Cheng ◽  
F N Nan ◽  
C M Wen



In Vitro ◽  
1980 ◽  
Vol 16 (11) ◽  
pp. 915-917 ◽  
Author(s):  
Goro Kuno


2016 ◽  
Vol 52 (4) ◽  
pp. 410-418 ◽  
Author(s):  
Pengfei Li ◽  
Lingli Zhou ◽  
Songwei Ni ◽  
Meng Xu ◽  
Yepin Yu ◽  
...  


2015 ◽  
Vol 87 (1) ◽  
pp. 115-122 ◽  
Author(s):  
Y. Zheng ◽  
L. M. Peng ◽  
F. You ◽  
Y. X. Zou ◽  
P. J. Zhang ◽  
...  






Endocrinology ◽  
2007 ◽  
Vol 148 (7) ◽  
pp. 3371-3382 ◽  
Author(s):  
Toni R. Pak ◽  
Wilson C. J. Chung ◽  
Laura R. Hinds ◽  
Robert J. Handa

Arginine vasopressin (AVP) is a neuropeptide involved in the regulation of fluid balance, stress, circadian rhythms, and social behaviors. In the brain, AVP is tightly regulated by gonadal steroid hormones in discrete regions with gonadectomy abolishing and testosterone replacement restoring normal AVP expression in adult males. Previous studies demonstrated that 17β-estradiol, a primary metabolite of testosterone, is responsible for restoring most of the AVP expression in the brain after castration. However, 5α-dihydrotestosterone (DHT) has also been shown to play a role in the regulation of AVP expression, thus implicating the involvement of both androgen and estrogen receptors (ER). Furthermore, DHT, through its conversion to 5α-androstane-3β,17β-diol, has been shown to modulate estrogen response element-mediated promoter activity through an ER pathway. The present study addressed two central hypotheses: 1) that androgens directly modulate AVP promoter activity and 2) the effect is mediated by an estrogen or androgen receptor pathway. To that end, we overexpressed androgen receptor, ERβ, and ERβ splice variants in a neuronal cell line and measured AVP promoter activity using a firefly luciferase reporter assay. Our results demonstrate that DHT and its metabolite 5α-androstane-3β,17β-diol stimulate AVP promoter activity through ERβ in a neuronal cell line.



Blood ◽  
1983 ◽  
Vol 62 (5) ◽  
pp. 1132-1134 ◽  
Author(s):  
JL Ascensao ◽  
F Gaylis ◽  
D Bronson ◽  
EE Fraley ◽  
ED Zanjani

Abstract An established human testis germ cell line (1411-H) was found to produce significant amounts of erythropoietin (Ep), the primary regulator of erythropoiesis. Media conditioned by the 1411-H cells stimulated erythropoiesis both in vivo and in vitro. This activity was neutralized by anti-Ep. This continuous cell line provides a unique model for the study of the mechanisms of control of Ep biogenesis.



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