Determination of chemical component of essential oil of Origanum dubium plants grown at different altitudes and antifungal activity against Sclerotinia sclerotiorum

The increase in dermatophytoses and the fact that some patients do not respond well to therapy make it necessary to find new antifungal agents. As part of our ongoing studies on medicinal plants from Iran, we studied antidermatophytic activities of Ferula latisecta essential oil, which had shown considerable antifungal activity in preliminary antimicrobial screening. Antifungal activity was evaluated by determination of MIC values using the agar dilution method on type strains of Candida albicans and dermatophytes. The composition of the oil was characterized by GC and GC/MS analyses. The essential oil was rich in polysulfides (75.2%) and exhibited good activity against Trichophyton rubrum and T. verrucosom for about three weeks, with a MIC value 96 μg/mL. The oil showed antifungal activity, especially against dermatophytes, and the activity is probably related to the sulfur-containing components of the oil. This study has identified that the polysulfides-rich essential oil of Ferula latisecta fruits has activity against a range of human pathogenic dermatophytes, justifying future clinical trials to validate its use as a therapeutic alternative for dermatophytosis.

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In Vitro Determination of the Antifungal Activity of Artemisia campestris Essential Oil from Algeria

International Journal of Food Properties ◽

10.1080/10942912.2015.1107734 ◽

2016 ◽

Vol 19 (8) ◽

pp. 1749-1756 ◽

Cited By ~ 10

Author(s):

Abderrahmane Houicher ◽

Hind Hechachna ◽

Fatih Özogul

Keyword(s):

Antifungal Activity ◽

Essential Oil ◽

Artemisia Campestris

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COMPOSIÇÃO QUÍMICA E ATIVIDADE ANTIFÚNGICA DO ÓLEO ESSENCIAL DE THYMUS VULGARIS SOBRE ASPERGILLUS NIGER, PENICILLIUM EXPANSUM, SCLEROTINIA SCLEROTIORUM E SCLEROTIUM ROLFSII / CHEMICAL COMPOSITION AND ANTIFUNGAL ACTIVITY OF THYMUS VULGARIS ESSENTIAL OIL ON ASPERGILLUS NIGER, PENICILLIUM EXPANSUM, SCLEROTINIA SCLEROTIORUM AND SCLEROTIUM ROLFSII

Brazilian Journal of Development ◽

10.34117/bjdv7n2-173 ◽

2021 ◽

Vol 7 (2) ◽

pp. 14250-14260

Author(s):

Cinthya Roberta Nunes ◽

Patrícia Moreira Valente ◽

Francisco Davi da Silva ◽

Vânia Maria Moreira Valente

Keyword(s):

Chemical Composition ◽

Antifungal Activity ◽

Aspergillus Niger ◽

Essential Oil ◽

Sclerotinia Sclerotiorum ◽

Sclerotium Rolfsii ◽

Penicillium Expansum ◽

Thymus Vulgaris

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Comparison of the composition and fungicidal activity of essential oils from fennel fruits cultivated in Poland and Egypt

Polish Journal of Chemical Technology ◽

10.2478/pjct-2019-0018 ◽

2019 ◽

Vol 21 (2) ◽

pp. 38-42

Author(s):

Alicja Wodnicka ◽

Elżbieta Huzar ◽

Małgorzata Dzięcioł ◽

Maria Krawczyk

Keyword(s):

Antifungal Activity ◽

Essential Oil ◽

Essential Oils ◽

Sclerotinia Sclerotiorum ◽

Plant Material ◽

Fungicidal Activity ◽

Pathogenic Fungi ◽

Main Component ◽

Essential Oil Yield

Abstract The yield, composition and fungicidal activity of essential oils obtained from fennel fruits cultivated in Poland (FEOPOL) and Egypt (FEO-EG) were compared. The influence of the duration of hydrodistillation using a Clevenger apparatus on the essential oil yield was studied. The composition of the fennel essential oils was determined by GC-MS method. Studies have shown that FEO-POL and FEO-EG are two distinct chemotypes, which differ in yield and composition. The fennel fruits cultivated in Poland contained 4.14% of essential oil with trans-anethole as a main component. The plant material from Egypt was characterised by low content of essential oil (1.32%) with a predominant share of estragole. The fungicidal activity was tested in vitro against ten species of pathogenic fungi. The best result for FEO-POL was achieved against Sclerotinia sclerotiorum, Rhizoctonia solani and Botrytis cinerea. Antifungal activity of FEO-EG against tested fungi was weak or none.

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Antifungal activity of Ziziphora clinopodioides Lam. essential oil against Sclerotinia sclerotiorum on rapeseed plants (Brassica campestris L.)

Crop Protection ◽

10.1016/j.cropro.2016.07.003 ◽

2016 ◽

Vol 89 ◽

pp. 289-295 ◽

Cited By ~ 12

Author(s):

Bing-Xin Ma ◽

Xiao-Quan Ban ◽

Jing-Sheng He ◽

Bo Huang ◽

Hong Zeng ◽

...

Keyword(s):

Antifungal Activity ◽

Essential Oil ◽

Sclerotinia Sclerotiorum ◽

Brassica Campestris

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Composição química dos óleos essenciais de Schinus molle e atividade antifúngica em Sclerotinia sclerotiorum

Colloquium Agrariae ◽

10.5747/ca.2020.v16.n3.a377 ◽

2020 ◽

Vol 16 (3) ◽

pp. 115-123

Author(s):

Antonio Carlos Pereira de Menezes Filho ◽

Wendel Cruvinel de Sousa ◽

Carlos Frederico de Souza Castro

Keyword(s):

Gas Chromatography ◽

Chemical Composition ◽

Antifungal Activity ◽

Essential Oil ◽

Essential Oils ◽

Sclerotinia Sclerotiorum ◽

White Mold ◽

Great Efficacy ◽

Chemical Profiles ◽

Type Apparatus

Schinus molleis popularly known as aroeira-salsa, with aromaticleaves and branches. The present study wasto evaluate the chemical composition ofthe essential oils fromthe branches and leaves from S. molleand,antifungal activity on the isolate fromSclerotinia sclerotiorum(white mold).The branches and leaves were collected and processed to extractessential oils by hydrodistillation in a Clevenger type apparatus. The yields from essential oils extraction,and their chemical profiles were evaluated by gas chromatography with mass spectrometry.The essential oils yields were 0.21 and 0.37%, with 16 and 21 compounds identified for the essential oils of the branches and leaves, respectively. The major compounds were δ-cadiene 21.77%, viridiflorol 21.74, copaene 12.9% and caryophyllene 9.99% for the essential oil of the branches, for essential oil of the leavesgermacrene D 39.00%, α-pinene 14.77%,and germacrene B 6.25%.The antifungal activity had mycelial inhibition in S. sclerotiorumin allevaluatedconcentrations, with emphasis on 100 μLmL-1,which had inhibition from86.4 and 81.3% for branches and leaves, respectively. The essential oils fromS. mollehad good yields and are rich in monoterpenics and sesquiterpenicscompounds, and have great efficacy inantifungal activity.

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Antifungal Activity of Topical Formulation Containing Artemisia Herba Alba Asso Essential Oil

Archives of Ecotoxicology ◽

10.36547/ae.2020.2.4.69-73 ◽

2020 ◽

Vol 2 (4) ◽

pp. 69-73

Author(s):

Asma Boukhennoufa ◽

Yamina Maizi ◽

Aicha Tir Touil Meddah ◽

Boumediene Meddah

Keyword(s):

Candida Albicans ◽

Antifungal Activity ◽

Essential Oil ◽

Ph Value ◽

Topical Formulation ◽

Synthetic Drugs ◽

Zones Of Inhibition ◽

Yeasts And Molds ◽

Indirect Source

Given the increase in antibiotic resistance phenomena and the undesirable effects of synthetic drugs. Medicinal plants are used as a direct or indirect source of the active ingredients. Our research constitutes a development of essential oils from Artemisia herba alba Asso cultivated in the Mascara region. A hydrophobic ointment has been formulated based on this essential oil and tested against five strains of Candida albicans. Several physicochemical and microbiological tests were used to verify the quality and the toxicity of the product. Then, the determination of the antifungal activity of this preparation was assessed against five strains of Candida albicans (S1, S2, S3, S4 and S5) by the disk-diffusion agar method. The results revealed that this preparation was devoid of total aerobic germs, yeasts and molds. However, the pH value was found equal to 5.98. In addition, the irritation primary index was marked less than 0.5. The ointment was powerful against S1, S3, S4 and S5 strains with inhibition diameters ranging from 16± 4 mm to 23 ± 2 mm. The Nystatin ointment was observed active against strains S2, S4 and S5 with diameters of the zones of inhibition; 21 ± 2 mm, 21± 1 mm and 20 ± 3 mm respectively. The ointment formulated with essential oil from Artemisia herba alba asso has proven useful against candidiasis caused by Candida albicans species.

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