Integrative Review of Co-Occurring Symptoms Across Etiologies of Chronic Liver Disease and Implications for Symptom Management Research and Practice

2015 ◽  
Vol 47 (4) ◽  
pp. 310-317 ◽  
Author(s):  
Kyungeh An ◽  
Nancy Jallo ◽  
Victoria Menzies ◽  
Patricia Kinser ◽  
Jo Lynne W. Robins ◽  
...  
2014 ◽  
Vol 17 (2) ◽  
pp. 222-229 ◽  
Author(s):  
Victoria Menzies ◽  
Nancy Jallo ◽  
Patricia Kinser ◽  
Jo Lynne W. Robins ◽  
Kyungeh An ◽  
...  

Liver disease affects over 25 million people in the United States and, despite advances in medical management resulting in increased survival, a majority of these individuals report multiple co-occurring symptoms that severely impair functioning and quality of life. The purpose of this review is to (1) propose defining these co-occurring symptoms as a symptom cluster of chronic liver disease (CLD), (2) discuss putative underlying biological mechanisms related to CLD, including the liver–gut–brain axis and influence of the microbiome, and (3) discuss the implications for biobehavioral research in this patient population. Biobehavioral research focusing on the interrelated, and possibly synergistic, mechanisms of these symptoms may lead to the development and testing of targeted symptom management interventions for improving function and quality of life in this growing patient population.


2001 ◽  
Vol 120 (5) ◽  
pp. A7-A7
Author(s):  
S ROSS ◽  
S MASCHERETTI ◽  
H HINRICHSEN ◽  
P BUGGISCH ◽  
U FOELSCH ◽  
...  

2013 ◽  
Vol 51 (01) ◽  
Author(s):  
B Czech ◽  
D Valletta ◽  
K Dettmer ◽  
M Müller ◽  
A Bosserhoff ◽  
...  

2014 ◽  
Vol 52 (08) ◽  
Author(s):  
S Krohn ◽  
C Engelmann ◽  
S Böhm ◽  
K Zeller ◽  
T Berg

2014 ◽  
Vol 52 (08) ◽  
Author(s):  
CS Stokes ◽  
F Gruenhage ◽  
C Baus ◽  
M Riemenschneider ◽  
F Lammert

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