Peutz–Jeghers syndrome complicated by gastric‐type cervical mucinous carcinoma and primary peritoneal carcinoma

2021 ◽  
Author(s):  
Saki Kotaka ◽  
Kiyoshi Kanno ◽  
Shiori Yanai ◽  
Masako Omori ◽  
Masaaki Andou
Keyword(s):  
Mucinous Carcinoma ◽  
Peritoneal Carcinoma ◽  
Primary Peritoneal Carcinoma ◽  
Gastric Type ◽  
Peutz Jeghers Syndrome

Primary peritoneal carcinoma in a young woman with suspected endometriosis

2009 ◽  
Vol 92 (1) ◽  
pp. 390.e5-390.e7 ◽  
Author(s):  
Constanze Banz ◽  
Sören von Otte ◽  
Frank Noack ◽  
Klaus Diedrich ◽  
Daniela Hornung
Keyword(s):  
Young Woman ◽  
Peritoneal Carcinoma ◽  
Primary Peritoneal Carcinoma

Intestinal lymphangiectasia mimicking primary peritoneal carcinoma

2010 ◽  
Vol 203 (4) ◽  
pp. e9-e11 ◽  
Author(s):  
Jennifer C. Steines ◽  
Joshua H. Larson ◽  
Neal Wilkinson ◽  
Patricia Kirby ◽  
Michael J. Goodheart
Keyword(s):  
Intestinal Lymphangiectasia ◽  
Peritoneal Carcinoma ◽  
Primary Peritoneal Carcinoma

Gastric-type adenocarcinoma of the cervix in patients with Peutz-Jeghers syndrome: a systematic review of the literature with proposed screening guidelines

2021 ◽  
pp. ijgc-2021-002997
Author(s):  
Sushmita B Gordhandas ◽  
Ryan Kahn ◽  
Dib Sassine ◽  
Emeline M Aviki ◽  
Becky Baltich Nelson ◽  
...  
Keyword(s):  
Systematic Review ◽  
Overall Survival ◽  
Pap Smear ◽  
Early Stage ◽  
Case Reports ◽  
High Risk Population ◽  
Normal Cytology ◽  
Presenting Symptoms ◽  
Gastric Type ◽  
Peutz Jeghers Syndrome

ObjectivesTo perform a systematic review of gastric-type adenocarcinoma of the cervix and lobular endocervical glandular hyperplasia (a possible precursor lesion) in Peutz-Jeghers syndrome, and to analyze data from the literature, along with our institutional experience, to determine recommendations for screening and detection.MethodsA comprehensive literature searc and retrospective search of pathology records at our institutio were conducted. Articles were screened by two independent reviewers. Case reports/series on lobular endocervical glandular hyperplasia/gastric-type adenocarcinoma of the cervix in Peutz-Jeghers syndrome were included. Demographic, clinical, and radiologic information was collected.ResultsA total of 1564 publications were reviewed; 38 met the inclusion criteria. Forty-nine were included in the analysis (43 from the literature, 6 from our institution). Forty-three reported on gastric-type adenocarcinoma alone, 4 on lobular endocervical glandular hyperplasia alone, and 2 on concurrent lobular endocervical glandular hyperplasia/gastric-type adenocarcinoma. Median age at diagnosis was 17 (range, 4–52) for patients with lobular endocervical glandular hyperplasia alone and 35 (range, 15–72) for those with gastric-type adenocarcinoma. The most common presenting symptoms were abdominal/pelvic pain and vaginal bleeding/discharge. Imaging was reported for 27 patients; 24 (89%) had abnormal cervical features. Papanicolaou (Pap) smear prior to diagnosis was reported for 12 patients; 6 (50%) had normal cytology, 4 (33%) atypical glandular cells, and 2 (17%) atypical cells not otherwise specified. Patients with gastric-type adenocarcinoma (n=45) were treated with surgery alone (n=16), surgery/chemotherapy/radiation (n=11), surgery/chemotherapy (n=9), surgery/radiation (n=5), or radiation/chemotherapy (n=4). Twelve (27%) of 45 patients recurred; median progression-free survival was 10 months (range, 1–148). Twenty patients (44%) died; median overall survival was 26 months (range, 2–156). Thirteen patients (27%) were alive with no evidence of disease.ConclusionsGastric-type adenocarcinoma in Peutz-Jeghers syndrome is associated with poor outcomes and short progression-free and overall survival. Screening recommendations, including pathognomonic symptom review and physical examination, with a low threshold for imaging and biopsy, may detect precursor lesions and early-stage gastric-type adenocarcinoma, leading to better outcomes in this high-risk population.PROSPERO registration numberCRD42019118151

Peritoneal Tuberculosis: A Retrospective Review of 20 Cases and Comparison With Primary Peritoneal Carcinoma

2010 ◽  
Vol 20 (5) ◽  
pp. 798-803 ◽  
Author(s):  
Chel Hun Choi ◽  
Chul-Jung Kim ◽  
Yoo-Young Lee ◽  
Joo Sun Kim ◽  
Taejong Song ◽  
...  
Keyword(s):  
Retrospective Review ◽  
Medical Center ◽  
Control Sample ◽  
Exploratory Laparotomy ◽  
Tissue Reaction ◽  
Ca 125 ◽  
Peritoneal Tuberculosis ◽  
Cancer Antigen 125 ◽  
Peritoneal Carcinoma ◽  
Primary Peritoneal Carcinoma

Introduction:To evaluate the clinical features of peritoneal tuberculosis (TB) and to compare them with those of primary peritoneal carcinoma (PPC).Methods:We conducted a retrospective review of women with peritoneal TB who were managed at Samsung Medical Center from January 1996 to October 2006. As a control sample, patients with a diagnosis of PPC during the same period were also selected for comparison.Results:During the study period, we identified 20 female patients with peritoneal TB. The median age was 39 years (range, 23-69 years), and the median cancer antigen 125 (CA-125) level was 448 U/mL (range, 32-1725 U/mL). Seventeen patients with PPC whom we examined were older, with a median age of 63 years (range, 50-73 years); their median CA-125 level was higher at 1848 U/mL (range, 42-14,380 U/mL). Compared with those of PPC, the radiologic findings of peritoneal TB indicated less severe involvement of the omentum and the mesentery (P = 0.03). Among the 20 patients who underwent operations, 6 (30%) underwent exploratory laparotomy; 12 (60%), diagnostic laparoscopy; and 2 (10%), laparoscopy converted to laparotomy because of severe adhesion. Frozen tissue sections revealed chronic granulomatous tissue reaction in 15 (83.3%) of 18 women with peritoneal TB.Conclusions:Maintaining a high index of suspicion is very important for the successful treatment of peritoneal TB, especially in developing countries. Age, CA-125 level, and omental involvement as identified by computed tomography may be helpful for the differential diagnosis of peritoneal TB and PPC.

scholarly journals Small Bowel Perforation Caused by Tumor Lysis after Chemotherapy for Primary Peritoneal Carcinoma

2017 ◽  
Vol 2 (1) ◽  
pp. 72-75 ◽  
Author(s):  
Hugo Bonatti ◽  
Frank D. Stegall ◽  
Allison Wasserman ◽  
W.H. Nealon
Keyword(s):  
Small Bowel ◽  
Bowel Perforation ◽  
Small Bowel Perforation ◽  
Peritoneal Carcinoma ◽  
Tumor Lysis ◽  
Primary Peritoneal Carcinoma
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