Peritoneal Tuberculosis: A Retrospective Review of 20 Cases and Comparison With Primary Peritoneal Carcinoma

2010 ◽  
Vol 20 (5) ◽  
pp. 798-803 ◽  
Author(s):  
Chel Hun Choi ◽  
Chul-Jung Kim ◽  
Yoo-Young Lee ◽  
Joo Sun Kim ◽  
Taejong Song ◽  
...  
Keyword(s):  
Retrospective Review ◽  
Medical Center ◽  
Control Sample ◽  
Exploratory Laparotomy ◽  
Tissue Reaction ◽  
Ca 125 ◽  
Peritoneal Tuberculosis ◽  
Cancer Antigen 125 ◽  
Peritoneal Carcinoma ◽  
Primary Peritoneal Carcinoma

Introduction:To evaluate the clinical features of peritoneal tuberculosis (TB) and to compare them with those of primary peritoneal carcinoma (PPC).Methods:We conducted a retrospective review of women with peritoneal TB who were managed at Samsung Medical Center from January 1996 to October 2006. As a control sample, patients with a diagnosis of PPC during the same period were also selected for comparison.Results:During the study period, we identified 20 female patients with peritoneal TB. The median age was 39 years (range, 23-69 years), and the median cancer antigen 125 (CA-125) level was 448 U/mL (range, 32-1725 U/mL). Seventeen patients with PPC whom we examined were older, with a median age of 63 years (range, 50-73 years); their median CA-125 level was higher at 1848 U/mL (range, 42-14,380 U/mL). Compared with those of PPC, the radiologic findings of peritoneal TB indicated less severe involvement of the omentum and the mesentery (P = 0.03). Among the 20 patients who underwent operations, 6 (30%) underwent exploratory laparotomy; 12 (60%), diagnostic laparoscopy; and 2 (10%), laparoscopy converted to laparotomy because of severe adhesion. Frozen tissue sections revealed chronic granulomatous tissue reaction in 15 (83.3%) of 18 women with peritoneal TB.Conclusions:Maintaining a high index of suspicion is very important for the successful treatment of peritoneal TB, especially in developing countries. Age, CA-125 level, and omental involvement as identified by computed tomography may be helpful for the differential diagnosis of peritoneal TB and PPC.

scholarly journals A Case of Disseminated Peritoneal Tuberculosis Mimicking Metastatic Ovarian Carcinoma

2014 ◽  
Vol 2 (1) ◽  
pp. 44-45 ◽  
Author(s):  
Ishita Mishra ◽  
Nimish C Pandya ◽  
Nilopher Surti ◽  
Babu S Patel
Keyword(s):  
Developing Countries ◽  
Ovarian Carcinoma ◽  
Exploratory Laparotomy ◽  
Reproductive Age ◽  
Ca 125 ◽  
Ovarian Malignancy ◽  
Peritoneal Tuberculosis ◽  
Cancer Antigen 125 ◽  
Diagnostic Modality ◽  
Major Health Problem

ABSTRACT Background Mycobacterium tuberculosis affects about 30% of world's population and infection occurs at a rate of one per second. In 2010, tuberculosis accounted for 8.8 million new cases, was responsible for 1.45 million deaths with majority of cases in developing countries. Tuberculosis is the most common cause of mortality in women of reproductive age. Peritoneal tuberculosis accounts for 4% of all extrapulmonary diseases and often mimics ovarian malignancy due to its nonspecific symptoms. Case A 25-year-old woman with ovarian mass and an elevated cancer antigen 125 (CA-125) underwent an exploratory laparotomy to search for ovarian tumor. The final pathological diagnosis was miliary abdominal tuberculosis. Discussion Peritoneal tuberculosis often mimics ovarian malignancy due to its nonspecific symptoms and is a major health problem in developing countries. There is no particular diagnostic test to differentiate this disease from advanced ovarian carcinoma, making it difficult to avoid extensive surgery. Laparoscopy is the diagnostic modality of choice. How to cite this article Surti N, Patel BS, Pandya NC, Mishra I. A Case of Disseminated Peritoneal Tuberculosis Mimicking Metastatic Ovarian Carcinoma. J South Asian Feder Menopause Soc 2014;2(1):44-45.

scholarly journals Diagnosis of Peritoneal Tuberculosis from Primary Peritoneal Cancer

2021 ◽  
Vol 18 (19) ◽  
pp. 10407
Author(s):  
I-Hui Chen ◽  
Pao-Ling Torng ◽  
Chia-Yi Lee ◽  
Kuang-Han Lee ◽  
Heng-Cheng Hsu ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Unique Feature ◽  
Medical Center ◽  
Ca 125 ◽  
Peritoneal Tuberculosis ◽  
Primary Peritoneal Cancer ◽  
Peritoneal Cancer ◽  
Radiological Features ◽  
Pulmonary Infiltration ◽  
Wbc Count

Peritoneal tuberculosis (PTB) is an uncommon extrapulmonary infection mimickng primary peritoneal cancer (PPC). We retrospectively included 23 women with PTB and 47 women with PPC treated in a medical center to study the clinical and radiological features that differentiate PTB from PPC. Body temperature above 38 °C was a unique feature of PTB (34.7% versus 0%, p < 0.001). Body Mass Index (BMI) was lower (21.9 ± 3.7 versus 25.2 ± 4.1, p = 0.003), white blood cell (WBC) count was lower (5179.6 ± 1502.2 versus 7716.2 ± 2741.8, p < 0.001), and CA-125 level was lower (508.0 ± 266.1 versus 2130.1 ± 2367.2 U/mL, p < 0.001) in PTB compared with PPC. Imaging detected more pulmonary infiltration and consolidation (52.2% versus 6.4%, p < 0.001), and less omental/mesentery changes (52% versus 83%, p < 0.001) in PTB compared with PPC. The operated patients received earlier treatment compared to patients without operation (7.9 ± 5.3 days versus 17.2 ± 11.0 days, p = 0.010). In conclusion, fever above 38 °C, lower BMI, lower WBC count, less elevated CA-125 level, and imaging of less omental involvement were features of PTB differentiated from PPC.

scholarly journals Primary peritoneal carcinoma with late-phase pulmonary metastases: a case report

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Naoki Ozeki ◽  
Shuhei Hakiri ◽  
Hisashi Tateyama ◽  
Kohei Yokoi ◽  
Toyofumi Chen-Yoshikawa
Keyword(s):  
Frozen Section ◽  
Late Phase ◽  
Left Lung ◽  
Primary Lung Cancer ◽  
Pulmonary Nodules ◽  
Cancer Antigen 125 ◽  
Peritoneal Carcinoma ◽  
Basal Segment ◽  
Primary Peritoneal Carcinoma ◽  
Standardized Uptake Values

Abstract Background Primary peritoneal carcinoma (PPC) is a very rare and aggressive type of malignancy with a poor prognosis. Case presentation A 66-year-old woman was referred to our hospital with two pulmonary nodules that developed after PPC resection and postoperative adjuvant chemotherapy administered 5 years earlier. Computed tomography revealed a 1.3-cm-sized nodule in the left lung with a small airspace in the posterior basal segment and a 0.9-cm-sized solid nodule in the apico-posterior segment that grew slightly within a 2-month period. 18F-Fluorodeoxyglucose-positron emission tomography of these lesions revealed respective maximum standardized uptake values of 7.11 and 2.46. Her serum cancer antigen-125 level remained within the normal range, despite elevation before the first surgery. The posterior basal segment and superior division were subjected to anatomical segmentectomy. An intraoperative frozen section examination could not distinguish metastatic PPC from primary lung cancer. Immunopathologically, the two nodules were identified as metastatic PPC. Conclusions Our findings suggest that PPC patients may develop late-phase thoracic recurrence that is difficult to diagnose clinically after initial treatment in a potentially resectable setting.

Improved overall survival for patients with advanced ovarian, tubal, and primary peritoneal carcinoma as a result of a change in surgical approach: A follow-up study

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 5530-5530
Author(s):  
D. S. Chi ◽  
E. L. Eisenhauer ◽  
Y. Sonoda ◽  
N. R. Abu-Rustum ◽  
M. L. Gemignani ◽  
...  
Keyword(s):  
Overall Survival ◽  
Fallopian Tube ◽  
Surgical Approach ◽  
Residual Disease ◽  
Ca 125 ◽  
Peritoneal Carcinoma ◽  
Primary Peritoneal Carcinoma ◽  
Group 2 ◽  
Upper Abdominal ◽  
Group 1

5530 Background: In January 2001, we initiated a programatic change in our primary surgical approach to advanced ovarian carcinoma utilizing extensive upper abdominal procedures as needed to achieve maximal cytoreduction. The objective of this study was to determine the impact of incorporating these procedures on overall survival in advanced ovarian, fallopian tube, and primary peritoneal carcinomas. Methods: Two groups of patients (pts) with stage IIIC and IV ovarian, tubal, and primary peritoneal carcinoma were identified for comparison. Group 1, the control group, consisted of all 168 pts who underwent primary cytoreduction between 1/96 and 12/99. Group 2, the study group, was composed of all 209 pts who underwent primary surgery between 1/01 and 12/04, during which time a more comprehensive debulking of upper abdominal disease was used, including diaphragm peritonectomy/resection, splenectomy, distal pancreatectomy, liver resection, resection of porta hepatis tumor, and cholecystectomy. Results: Comparison between the 2 groups revealed no significant difference in age, BMI, performance status, stage, tumor grade, proportion with primary ovarian cancer, preoperative CA-125 levels, preoperative platelet counts, percentage with ascites, or type of postoperative primary chemotherapy. The only 2 variables that differed significantly between the 2 groups were percentage of pts who had extensive upper abdominal surgery and percentage of pts cytoreduced to ≤1 cm residual disease (RD). Patients in Group 2 were more likely to have undergone extensive upper abdominal procedure(s) (37% vs. 1%; P <0.001). Cytoreduction to RD ≤1 cm was achieved in 50% of Group 1 pts compared to 80% of Group 2 pts (P <0.01). Overall median survival was significantly improved in Group 2 versus Group 1 pts (58 vs. 43 mos, [P=0.042], respectively). Conclusions: The recent incorporation of extensive upper abdominal surgical procedures to increase the rate of primary cytoreduction to residual disease ≤1 cm resulted in significantly improved overall survival. A paradigm shift toward more complete primary cytoreduction can improve survival for pts with advanced ovarian, fallopian tube, and primary peritoneal carcinomas. No significant financial relationships to disclose.

scholarly journals The prognostic and predictive value of CA-125 regression during neoadjuvant chemotherapy for advanced ovarian or primary peritoneal carcinoma

2010 ◽  
Vol 284 (1) ◽  
pp. 221-227 ◽  
Author(s):  
Naveen S. Vasudev ◽  
Ioannis Trigonis ◽  
David A. Cairns ◽  
Geoff D. Hall ◽  
David P. Jackson ◽  
...  
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Predictive Value ◽  
Ca 125 ◽  
Peritoneal Carcinoma ◽  
Primary Peritoneal Carcinoma

Meigs syndrome presenting with severely elevated CA-125 level

2021 ◽  
Vol 14 (3) ◽  
pp. e238931
Author(s):  
Alicia Palmieri ◽  
Karim ElSahwi ◽  
Verda Hicks
Keyword(s):  
Pleural Effusion ◽  
Ovarian Carcinoma ◽  
Pelvic Mass ◽  
Exploratory Laparotomy ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Ca 125 ◽  
Cancer Antigen 125 ◽  
Laboratory Findings ◽  
Pathological Evaluation

A 64-year-old woman referred to Gynaecological Oncology secondary to the finding of pelvic mass and ascites. Imaging showed multiple pelvic masses, with the largest mass measuring 20 cm in diameter, as well as bilateral pleural effusions and abdominal ascites, suspicious for ovarian carcinoma. Laboratory findings included elevated cancer antigen 125 (CA-125) of 2124 units/mL. The patient underwent an exploratory laparotomy, total abdominal hysterectomy and bilateral salpingo-oophorectomy for pathological evaluation. Postoperatively, the patient had resolution of ascites and pleural effusion. Surgical pathology revealed a 26 cm right ovarian fibroma, confirming the diagnosis of Meigs syndrome. Despite the high suspicion for ovarian carcinoma in patients presenting with elevated CA-125 level, pelvic mass, ascites and pleural effusion, the diagnosis of Meigs syndrome cannot be excluded without pathological evaluation of mass.

Sign in / Sign up

Export Citation Format

Share Document