Multidisciplinary rehabilitation treatment versus cognitive behavioural therapy for patients with chronic fatigue syndrome: a randomized controlled trial

2015 ◽  
Vol 279 (3) ◽  
pp. 268-282 ◽  
Author(s):  
D. C. W. M. Vos-Vromans ◽  
R. J. E. M. Smeets ◽  
I. P. J. Huijnen ◽  
A. J. A. Köke ◽  
W. M. G. C. Hitters ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Chronic Fatigue Syndrome ◽  
Cognitive Behavioural Therapy ◽  
Controlled Trial ◽  
Chronic Fatigue ◽  
Behavioural Therapy ◽  
Rehabilitation Treatment ◽  
Randomized Controlled ◽  
Fatigue Syndrome ◽  
Cognitive Behavioural

scholarly journals Efficacy of web-based cognitive–behavioural therapy for chronic fatigue syndrome: randomised controlled trial

2018 ◽  
Vol 212 (2) ◽  
pp. 112-118 ◽  
Author(s):  
A. Janse ◽  
M. Worm-Smeitink ◽  
G. Bleijenberg ◽  
R. Donders ◽  
H. Knoop
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Cognitive Behavioural Therapy ◽  
Controlled Trial ◽  
Chronic Fatigue ◽  
Behavioural Therapy ◽  
Waiting List ◽  
Face To Face ◽  
On Demand ◽  
Fatigue Syndrome ◽  
Cognitive Behavioural

BackgroundFace-to-face cognitive–behavioural therapy (CBT) leads to a reduction of fatigue in chronic fatigue syndrome (CFS).AimsTo test the efficacy of internet-based CBT (iCBT) for adults with CFS.MethodA total of 240 patients with CFS were randomised to either iCBT with protocol-driven therapist feedback or with therapist feedback on demand, or a waiting list. Primary outcome was fatigue severity assessed with the Checklist Individual Strength (Netherlands Trial Register: NTR4013).ResultsCompared with a waiting list, intention-to-treat (ITT) analysis showed a significant reduction of fatigue for both iCBT conditions (protocol-driven feedback: B = −8.3, 97.5% CI −12.7 to −3.9, P < 0.0001; feedback on demand: B = −7.2, 97.5% CI −11.3 to –3.1, P < 0.0001). No significant differences were found between both iCBT conditions on all outcome measures (P = 0.3–0.9). An exploratory analysis revealed that feedback-on-demand iCBT required less therapist time (mean 4 h 37 min) than iCBT with protocol-driven feedback (mean 6 h 9 min, P < 0.001) and also less than face-to-face CBT as reported in the literature.ConclusionsBoth iCBT conditions are efficacious and time efficient.Declaration of interestNone.

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