scholarly journals Nerve growth factor‐induced migration in oral and salivary gland tumour cells utilises the PI3K/Akt signalling pathway: Is there a link to perineural invasion?

2019 ◽  
Vol 49 (3) ◽  
pp. 227-234 ◽  
Author(s):  
Huda Alkhadar ◽  
Michaelina Macluskey ◽  
Sharon White ◽  
Ian Ellis
Keyword(s):  
Salivary Gland ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Perineural Invasion ◽  
Tumour Cells ◽  
Signalling Pathway ◽  
Salivary Gland Tumour ◽  
Nerve Growth ◽  
Gland Tumour

Presence of nerve growth factor-like immunoreactivity in carcinoid tumour cells and induction of a neuronal phenotype in long-term culture

1989 ◽  
Vol 43 (5) ◽  
pp. 949-955 ◽  
Author(s):  
Håkan Ahlman ◽  
Anneli Wigander ◽  
Johan Möulne ◽  
Ola Nilsson ◽  
Jan Erik Karlsson ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Carcinoid Tumour ◽  
Tumour Cells ◽  
Neuronal Phenotype ◽  
Nerve Growth ◽  
Long Term Culture

Nerve Growth Factor Signals as Possible Pathogenic Biomarkers for Perineural Invasion in Adenoid Cystic Carcinoma

2015 ◽  
Vol 153 (2) ◽  
pp. 218-224 ◽  
Author(s):  
Kenya Kobayashi ◽  
Mizuo Ando ◽  
Yuki Saito ◽  
Kenji Kondo ◽  
Go Omura ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Adenoid Cystic Carcinoma ◽  
Perineural Invasion ◽  
Nerve Growth ◽  
Adenoid Cystic

Nerve Growth Factor mediates its pro-invasive effect in parallel with the release of a soluble E-cadherin fragment from breast cancer MCF-7/AZ cells

2005 ◽  
Vol 72 (S1) ◽  
pp. 20-26 ◽  
Author(s):  
Laurent Dollé ◽  
Maria-José Oliveira ◽  
Erik Bruyneel ◽  
Hubert Hondermarck ◽  
Marc Bracke
Keyword(s):  
Breast Cancer ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Cancer Progression ◽  
Breast Cancer Cells ◽  
Complex Function ◽  
Tumour Cells ◽  
Nerve Growth ◽  
Mcf 7 ◽  
E Cadherin

To define better the function of Nerve Growth Factor (NGF) in breast cancer progression, we investigated whether this polypeptide was able to induce breast cancer cell invasion. NGF inhibited aggregation of tumour cells through modulation of the E-cadherin/catenin complex function. In addition, NGF induced the breast cancer cells to invade into Matrigel. We focused our attention on how NGF prevents aggregation, in order to discover the signalling pathway that leads tumour cells to acquire the invasive phenotype. Moreover, studies on the identification of signalling pathways that are responsive for NGF-induced invasion will be basically described.

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