Oxidative pathways in response to polyunsaturated aldehydes in the marine diatom Skeletonema marinoi (Bacillariophyceae)

2016 ◽  
Vol 52 (4) ◽  
pp. 590-598 ◽  
Author(s):  
Alessandra A. Gallina ◽  
Anna Palumbo ◽  
Raffaella Casotti
Keyword(s):  
Marine Diatom ◽  
Polyunsaturated Aldehydes ◽  
Skeletonema Marinoi

Impact of irradiance on the C allocation in the coastal marine diatom Skeletonema marinoi Sarno and Zingone*

2011 ◽  
Vol 34 (10) ◽  
pp. 1666-1677 ◽  
Author(s):  
ALESSANDRA NORICI ◽  
ANNA MARIA BAZZONI ◽  
ALESSANDRA PUGNETTI ◽  
JOHN A. RAVEN ◽  
MARIO GIORDANO
Keyword(s):  
Marine Diatom ◽  
Coastal Marine ◽  
Coastal Marine Diatom ◽  
Skeletonema Marinoi

scholarly journals Complete Genome Sequence of Novel Sulfitobacter pseudonitzschiae Strain SMR1, Isolated from a Culture of the Marine Diatom Skeletonema marinoi

2019 ◽  
Vol 7 ◽  
pp. 7-10 ◽  
Author(s):  
Mats Töpel ◽  
Matthew I.M. Pinder ◽  
Oskar N. Johansson ◽  
Olga Kourtchenko ◽  
Adrian K. Clarke ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Marine Diatom ◽  
Skeletonema Marinoi

scholarly journals Exploring Molecular Signs of Sex in the Marine Diatom Skeletonema marinoi

Genes ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 494 ◽  
Author(s):  
Ferrante ◽  
Entrambasaguas ◽  
Johansson ◽  
Töpel ◽  
Kremp ◽  
...  
Keyword(s):  
Sexual Reproduction ◽  
Reduction Process ◽  
Life Cycles ◽  
Marine Diatom ◽  
Centric Diatom ◽  
Rna Seq ◽  
Pennate Diatom ◽  
Planktonic Diatom ◽  
Expression Of Genes ◽  
Skeletonema Marinoi

Sexual reproduction plays a fundamental role in diatom life cycles. It contributes to increasing genetic diversity through meiotic recombination and also represents the phase where large-sized cells are produced to counteract the cell size reduction process that characterizes these microalgae. With the aim to identify genes linked to the sexual phase of the centric planktonic diatom Skeletonema marinoi, we carried out an RNA-seq experiment comparing the expression level of transcripts in sexualized cells with that of large cells not competent for sex. A set of genes involved in meiosis were found upregulated. Despite the fact that flagellate gametes were observed in the sample, we did not detect the expression of genes involved in the synthesis of flagella that were upregulated during sexual reproduction in another centric diatom. A comparison with the set of genes changing during the first phases of sexual reproduction of the pennate diatom Pseudo-nitzschia multistriata revealed the existence of commonalities, including the strong upregulation of genes with an unknown function that we named Sex Induced Genes (SIG). Our results further broadened the panel of genes that can be used as a marker for sexual reproduction of diatoms, crucial for the interpretation of metatranscriptomic datasets.

scholarly journals Dynamics of Dissolved and Particulate Polyunsaturated Aldehydes in Mesocosms Inoculated with Different Densities of the Diatom Skeletonema marinoi

Marine Drugs ◽  
2011 ◽  
Vol 9 (3) ◽  
pp. 345-358 ◽  
Author(s):  
Charles Vidoudez ◽  
Jens Christian Nejstgaard ◽  
Hans Henrik Jakobsen ◽  
Georg Pohnert
Keyword(s):  
Polyunsaturated Aldehydes ◽  
Skeletonema Marinoi

PLASTICITY OF OXYLIPIN METABOLISM AMONG CLONES OF THE MARINE DIATOM SKELETONEMA MARINOI (BACILLARIOPHYCEAE)1

2011 ◽  
Vol 47 (5) ◽  
pp. 1050-1056 ◽  
Author(s):  
Andrea Gerecht ◽  
Giovanna Romano ◽  
Adrianna Ianora ◽  
Giuliana d’Ippolito ◽  
Adele Cutignano ◽  
...  
Keyword(s):  
Marine Diatom ◽  
Skeletonema Marinoi

scholarly journals Complete Genome Sequence of the Diatom-Associated Bacterium Sphingorhabdus sp. Strain SMR4y

2019 ◽  
Vol 8 (29) ◽  
Author(s):  
Mats Töpel ◽  
Matthew I. M. Pinder ◽  
Oskar N. Johansson ◽  
Olga Kourtchenko ◽  
Anna Godhe ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Bacterial Strain ◽  
Complete Genome ◽  
Marine Diatom ◽  
Circular Chromosome ◽  
Coding Sequences ◽  
Content Type ◽  
Skeletonema Marinoi

The bacterial strain SMR4y belongs to the diverse microbiome of the marine diatom Skeletonema marinoi strain R05AC. After assembly of its genome, presented here, and subsequent analyses, we placed it in the genus Sphingorhabdus. This strain has a 3,479,724-bp circular chromosome (with 3,340 coding sequences) and no known plasmids.

scholarly journals Monoacylglycerides from the Diatom Skeletonema marinoi Induce Selective Cell Death in Cancer Cells

Marine Drugs ◽  
2019 ◽  
Vol 17 (11) ◽  
pp. 625 ◽  
Author(s):  
Marco Miceli ◽  
Adele Cutignano ◽  
Mariarosaria Conte ◽  
Raffaella Ummarino ◽  
Alessandra Romanelli ◽  
...  
Keyword(s):  
Cell Death ◽  
Cell Line ◽  
Cancer Cell ◽  
Large Scale ◽  
Cancer Cell Line ◽  
Marine Diatom ◽  
Scale Production ◽  
Natural Form ◽  
Hct 116 ◽  
Skeletonema Marinoi

Microalgae are an excellent source of valuable compounds for nutraceutical and cosmeceutical applications. These photosynthesizing microorganisms are amenable for large-scale production, thus overcoming the bottleneck of biomass supply for chemical and activity characterization of bioactive compounds. This characteristic has recently also prompted the screening of microalgae for potential pharmaceutical applications. Here, we show that monoacylglycerides (MAGs) purified from the marine diatom Skeletonema marinoi have selective cytotoxic activity against the haematological cancer cell line U-937 and colon cancer cell line HCT-116 compared to normal MePR-2B cells. LC-MS analysis of the raw extract revealed that in their natural form, MAGs occur as 2-monoacyl derivatives and include mainly C16 and C20 analogues, but they are converted into the corresponding 1-isomers during purification processes. Pure compounds along with the synthetic 1-monoarachidonoylglycerol tested on HCT-116 and U-937 tumor cell lines induced cell death via apoptosis. The mechanism of action was investigated, and we show that it involves the induction of apoptosis through caspase 3/7 activation. These findings pave the way for the possible use of these molecules as potential anticancer agents or as precursors for the generation of new and more potent and selective compounds against tumor cells.

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