scholarly journals Chronic kidney disease progression in kidney transplant recipients: A focus on traditional risk factors

Nephrology ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 141-147 ◽  
Author(s):  
Moisés Carminatti ◽  
Hélio Tedesco-Silva ◽  
Natália Maria Silva Fernandes ◽  
Helady Sanders-Pinheiro
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Disease Progression ◽  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Chronic Kidney Disease Progression ◽  
Kidney Disease Progression ◽  
Traditional Risk Factors

scholarly journals Central Blood Pressure and Chronic Kidney Disease Progression

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Debbie L. Cohen ◽  
Raymond R. Townsend
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Disease Progression ◽  
Pulse Wave ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Chronic Kidney Disease Progression ◽  
Patients At Risk ◽  
Kidney Disease Progression

Hypertension, diabetes, and proteinuria are well-recognized risk factors for progressive kidney function loss. However, despite excellent antihypertensive and antidiabetic drug therapies, which also often lower urinary protein excretion, there remains a significant reservoir of patients with chronic kidney disease who are at high risk for progression to end-stage kidney disease. This has led to the search for less traditional cardiovascular risk factors that will help stratify patients at risk for more rapid kidney disease progression. Among these are noninvasive estimates of vascular structure and function. Arterial stiffness, manifested by the pulse wave velocity in the aorta, has been established in a number of studies as a significant risk factor for kidney disease progression and cardiovascular endpoints. Much less well studied in chronic kidney disease are measures of central arterial pressures. In this paper we cover the physiology behind the generation of the central pulse wave contour and the studies available using these approaches and conclude with some speculations on the rationale for why measurements of central pressure may be informative for the study of chronic kidney disease progression.

scholarly journals The Protective Role of Protocol Biopsy for Allograft Kidney Maintenance in Kidney Transplantation

2021 ◽  
Author(s):  
Okjoo Lee ◽  
Kyo Won Lee ◽  
Jae Berm Park ◽  
Jung Eun Lee ◽  
Na Young Hwang ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Kidney Transplant ◽  
Graft Survival ◽  
Graft Function ◽  
Protective Role ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Protocol Biopsy ◽  
Kidney Disease Progression

Abstract Many studies have reported that protocol biopsy (PB) may help preserve kidney function in kidney transplant recipients. Early detection and treatment of subclinical rejection may reduce the incidence of chronic allograft nephropathy and graft failure. However, no consensus has been reached regarding PB effectiveness, timing, and policy. This study aimed to evaluate the protective role of routine PB performed 2 weeks and 1 year after kidney transplantation. We reviewed 854 kidney transplant recipients at the Samsung Medical Center between July 2007 and August 2017, with PBs planned at 2 weeks and 1 year after transplantation. We compared the trends in graft function, chronic kidney disease progression, new-onset chronic kidney disease, infection, and patient and graft survival between the 504 patients who underwent PB and 350 who did not undergo PB. The PB group was again divided into two groups: the single PB group (n = 207) and the double PB group (n = 297). In the PB group, the donors and recipients were significantly older and there was a greater presence of recipient diabetes mellitus and donor hypertension, donor-specific antigen, and a higher proportion of ABO-incompatible kidney transplantations. The PB group was significantly different from the no-PB group in terms of the trends in graft function (estimated glomerular filtration rate). The Kaplan-Meier curve showed that PB did not significantly improve graft survival or overall patient survival. However, in the multivariate Cox analysis, the double PB group had advantages in graft survival, chronic kidney disease progression, and new-onset chronic kidney disease. PB can play a protective role in the maintenance of kidney grafts in kidney transplant recipients.

scholarly journals Prospective cohort analyzing risk factors for chronic kidney disease progression in children

2018 ◽  
Vol 94 (5) ◽  
pp. 525-531 ◽  
Author(s):  
Vera M.S. Belangero ◽  
Liliane C. Prates ◽  
Andreia Watanabe ◽  
Benita S.G. Schvartsman ◽  
Paula Nussenzveig ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Disease Progression ◽  
Prospective Cohort ◽  
Chronic Kidney Disease Progression ◽  
Kidney Disease Progression

624 Chronic Kidney Disease Progression and Mortality in Liver Transplant Recipients

2013 ◽  
Vol 144 (5) ◽  
pp. S-955-S-956
Author(s):  
Alina M. Allen ◽  
W. Ray Kim ◽  
Terry M. Therneau ◽  
Chun Fan ◽  
Andrew D. Rule ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Liver Transplant ◽  
Disease Progression ◽  
Transplant Recipients ◽  
Chronic Kidney Disease Progression ◽  
Kidney Disease Progression ◽  
Liver Transplant Recipients

scholarly journals Prospective cohort analyzing risk factors for chronic kidney disease progression in children

2018 ◽  
Vol 94 (5) ◽  
pp. 525-531
Author(s):  
Vera M.S. Belangero ◽  
Liliane C. Prates ◽  
Andreia Watanabe ◽  
Benita S.G. Schvartsman ◽  
Paula Nussenzveig ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Disease Progression ◽  
Prospective Cohort ◽  
Chronic Kidney Disease Progression ◽  
Kidney Disease Progression
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