Gastro-esophageal reflux and antisecretory drugs use among patients with chronic autoimmune atrophic gastritis: a study with pH-impedance monitoring

2015 ◽  
Vol 28 (2) ◽  
pp. 274-280 ◽  
Author(s):  
A. Tenca ◽  
S. Massironi ◽  
D. Pugliese ◽  
D. Consonni ◽  
A. Mauro ◽  
...  
Keyword(s):  
Atrophic Gastritis ◽  
Esophageal Reflux ◽  
Antisecretory Drugs ◽  
Impedance Monitoring ◽  
Autoimmune Atrophic Gastritis

scholarly journals Esophageal chemical clearance and baseline impedance values in patients with chronic autoimmune atrophic gastritis and gastro-esophageal reflux disease

2017 ◽  
Vol 49 (9) ◽  
pp. 978-983 ◽  
Author(s):  
Andrea Tenca ◽  
Nicola de Bortoli ◽  
Aurelio Mauro ◽  
Marzio Frazzoni ◽  
Edoardo Savarino ◽  
...  
Keyword(s):  
Atrophic Gastritis ◽  
Reflux Disease ◽  
Esophageal Reflux ◽  
Autoimmune Atrophic Gastritis

T01.01.12 ANTI-PARIETAL CELL ANTIBODIES MAY BE NEGATIVE DESPITE HISTOLOGICAL CONFIRMATION OF AUTOIMMUNE ATROPHIC GASTRITIS: ROLE OF OLDER AGE

2020 ◽  
Vol 52 ◽  
pp. S56-S57
Author(s):  
L. Conti ◽  
M.V. Lenti ◽  
A. Di Sabatino ◽  
E. Miceli ◽  
G. Galli ◽  
...  
Keyword(s):  
Atrophic Gastritis ◽  
Parietal Cell ◽  
Older Age ◽  
Parietal Cell Antibodies ◽  
Autoimmune Atrophic Gastritis ◽  
Histological Confirmation

Su1146 Intense Gastro-Esophageal Reflux May Influence the Localization of Barrett's Adenocarcinoma: Measured by 24-h pH-Impedance Monitoring

2016 ◽  
Vol 150 (4) ◽  
pp. S483
Author(s):  
Masahiro Saito ◽  
Tomoyuki Koike ◽  
Hiroki Kikuchi ◽  
Kazuaki Norita ◽  
Kenichirou Nakagawa ◽  
...  
Keyword(s):  
Esophageal Reflux ◽  
Barrett’S Adenocarcinoma ◽  
Impedance Monitoring

scholarly journals Proteomics signature of autoimmune atrophic gastritis: towards a link with gastric cancer

2021 ◽  
Author(s):  
Ombretta Repetto ◽  
Valli De Re ◽  
Paolo Giuffrida ◽  
Marco Vincenzo Lenti ◽  
Raffaella Magris ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Atrophic Gastritis ◽  
Tricarboxylic Acid Cycle ◽  
Differential Abundance ◽  
Expression Levels ◽  
2D Dige ◽  
Gastric Corpus ◽  
Gastric Biopsies ◽  
H Pylori ◽  
Autoimmune Atrophic Gastritis

Abstract Background Autoimmune atrophic gastritis (AAG) is a chronic disease that can progress to gastric cancer (GC). To better understand AAG pathology, this proteomics study investigated gastric proteins whose expression levels are altered in this disease and also in GC. Methods Using two-dimensional difference gel electrophoresis (2D-DIGE), we compared protein maps of gastric corpus biopsies from AAG patients and controls. Differentially abundant spots (|fold change|≥ 1.5, P < 0.01) were selected and identified by LC–MS/MS. The spots were further assessed in gastric antrum biopsies from AAG patients (without and with Helicobacter pylori infection) and from GC patients and unaffected first-degree relatives of GC patients. Results 2D-DIGE identified 67 differentially abundant spots, with 28 more and 39 less abundant in AAG-corpus than controls. LC–MS/MS identified these as 53 distinct proteins. The most significant (adjusted P < 0.01) biological process associated with the less abundant proteins was “tricarboxylic acid cycle”. Of the 67 spots, 57 were similarly differentially abundant in AAG-antrum biopsies irrespective of H. pylori infection status. The differential abundance was also observed in GC biopsies for 14 of 28 more abundant and 35 of 39 less abundant spots, and in normal gastric biopsies of relatives of GC patients for 6 and 25 spots, respectively. Immunoblotting confirmed the different expression levels of two more abundant proteins (PDIA3, GSTP gene products) and four less abundant proteins (ATP5F1A, PGA3, SDHB, PGC). Conclusion This study identified a proteomics signature of AAG. Many differential proteins were shared by GC and may be involved in the progression of AAG to GC.

scholarly journals Validation of diagnostic strategies of autoimmune atrophic gastritis: A case report

2021 ◽  
Vol 9 (31) ◽  
pp. 9557-9563
Author(s):  
Wen-Jing Sun ◽  
Qiang Ma ◽  
Ren-Zheng Liang ◽  
Ya-Mei Ran ◽  
Li Zhang ◽  
...  
Keyword(s):  
Case Report ◽  
Atrophic Gastritis ◽  
Diagnostic Strategies ◽  
Autoimmune Atrophic Gastritis

Autoimmune atrophic gastritis in systemic sclerosis

2021 ◽  
Vol 14 (8) ◽  
pp. e242851
Author(s):  
Deepti Avasthi ◽  
Jean Thomas ◽  
Leela Krishna Vamsee Miriyala ◽  
Salil Avasthi
Keyword(s):  
Systemic Sclerosis ◽  
Connective Tissue ◽  
Literature Review ◽  
Atrophic Gastritis ◽  
Vascular Dysfunction ◽  
Connective Tissue Disorder ◽  
Gastric Antral Vascular Ectasia ◽  
Innate And Adaptive Immunity ◽  
Common Presentation ◽  
Autoimmune Atrophic Gastritis

Systemic sclerosis (SSc) is a rare connective tissue disorder with a complex pathogenesis involving vascular dysfunction, small vessel proliferation as well as alterations of innate and adaptive immunity. Gastrointestinal (GI) involvement in SSc is almost universal and affects nearly 90% of the patients. Of all the GI manifestations, 30%–75% are oesophageal abnormalities, including gastro-oesophageal reflux disease, reflux oesophagitis and Barret’s oesophagus. The incidence of gastric manifestations is about 22% with a common presentation of gastric antral vascular ectasia (GAVE). However, autoimmune atrophic gastritis (AIG) is not a known manifestation of SSc. Our case has a unique presentation of the coexistence of GAVE and AIG. We have conducted a thorough literature review to study a possible association of AIG and SSc and understand the pathology of SSc.

OC.06.6 CHARACTERISATION OF IMMUNE CELLS INFILTRATING THE CORPUS MUCOSA OF THE STOMACH IN AUTOIMMUNE ATROPHIC GASTRITIS

2019 ◽  
Vol 51 ◽  
pp. e93
Author(s):  
P. Giuffrida ◽  
F. Facciotti ◽  
M.V. Lenti ◽  
A. Pasini ◽  
S. Cococcia ◽  
...  
Keyword(s):  
Atrophic Gastritis ◽  
Immune Cells ◽  
Autoimmune Atrophic Gastritis

Natural history of autoimmune atrophic gastritis: a prospective, single centre, long-term experience

2019 ◽  
Vol 50 (11-12) ◽  
pp. 1172-1180 ◽  
Author(s):  
Emanuela Miceli ◽  
Alessandro Vanoli ◽  
Marco Vincenzo Lenti ◽  
Catherine Klersy ◽  
Michele Di Stefano ◽  
...  
Keyword(s):  
Natural History ◽  
Atrophic Gastritis ◽  
Single Centre ◽  
History Of ◽  
Autoimmune Atrophic Gastritis ◽  
Long Term Experience

Impaired Quality of Life in Patients with Autoimmune Atrophic Gastritis

2020 ◽  
Author(s):  
Emanuela Miceli ◽  
Natascia Brondino ◽  
Marco Vincenzo Lenti ◽  
Michele Di Stefano ◽  
Martina Staiani ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Atrophic Gastritis ◽  
Autoimmune Atrophic Gastritis ◽  
Impaired Quality
Sign in / Sign up

Export Citation Format

Share Document