scholarly journals Irritable Bowel Syndrome: Straightening the road from the Rome criteria

2020 ◽  
Vol 32 (11) ◽  
Author(s):  
Michael Camilleri
Gut ◽  
1998 ◽  
Vol 43 (2) ◽  
pp. 256-261 ◽  
Author(s):  
E J Bennett ◽  
C C Tennant ◽  
C Piesse ◽  
C-A Badcock ◽  
J E Kellow

Background—Life stress contributes to symptom onset and exacerbation in the majority of patients with irritable bowel syndrome (IBS) and functional dyspepsia (FD); research evidence is conflicting, however, as to the strength of these effects.Aims—To test prospectively the relation of chronic life stress threat to subsequent symptom intensity over time.Patients—One hundred and seventeen consecutive outpatients satisfying the modified Rome criteria for IBS (66% with one or more concurrent FD syndromes) participated.Methods—The life stress and symptom intensity measures were determined from interview data collected independently at entry, and at six and 16 months; these measures assessed the potency of chronic life stress threat during the prior six months or more, and the severity and frequency of IBS and FD symptoms during the following two weeks.Results—Chronic life stress threat was a powerful predictor of subsequent symptom intensity, explaining 97% of the variance on this measure over 16 months. No patient exposed to even one chronic highly threatening stressor improved clinically (by 50%) over the 16 months; all patients who improved did so in the absence of such a stressor.Conclusion—The level of chronic life stress threat predicts the clinical outcome in most patients with IBS/FD.


2008 ◽  
Vol 103 ◽  
pp. S471-S472
Author(s):  
Yuri Saito-Loftus ◽  
Ann Almazar-Elder ◽  
Joseph Larson ◽  
Elizabeth Atkinson ◽  
Nicholas Talley

2008 ◽  
Vol 134 (4) ◽  
pp. A-467 ◽  
Author(s):  
Alexander C. Ford ◽  
Nicholas J. Talley ◽  
Sander Veldhuyzen van Zanten ◽  
Nimish Vakil ◽  
Paul Moayyedi

2019 ◽  
pp. 110-116
Author(s):  
D. I. Trukhan ◽  
V. V. Goloshubina ◽  
D. S. Ivanova

The problem of irritable bowel syndrome (IBS) remains relevant for practice internist and gastroenterologist, as evidenced by the large number of publications in recent years on this issue, affecting various aspects of the pathogenesis, clinical manifestations, diagnosis and treatment of IBS. The article describes the evolution of diagnostic criteria for IBS as part of an international consensus «Rome criteria». Lack of effect of the treatment of IBS ex juvantibus often not a consequence of an incorrect diagnosis, and due to the presence in the patient’s intestinal disorders microbiocenosis. In this situation, it is expedient to correct the microbial landscape of the intestine with the use of probiotic agents. Efficacy in reducing the symptoms of irritable bowel syndrome has reliably demonstrated specific strains of probiotics, such as Bifidobacterium infantis 35624.


2020 ◽  
Vol 16 (1) ◽  
pp. 10-17
Author(s):  
Zaid I. Al-Attar

Background: Irritable bowel syndrome (IBS) is one of the most common GI disorders in people under 50 years of age.Objective: To Formulate an overview about demographics of IBS and patterns of presentation, to determine IBS patients severity ranking, and to recognize the main regimens with their patient satisfaction.Methods: This is a cross sectional clinical study that is conducted in Outpatient Consultant Internal Medicine Clinic in Al-Kindy Teaching Hospital from 11/12/2017 to 24/12/2017. The patients suffering from IBS are diagnosed by a consultant according to the symptom-based Rome criteria for functional GI disorders, by implementing a questionnaire collecting thorough information. 77 cases of IBS patients were collected (24 male and 53 female).Results: This study revealed that majority of patients were female (68.8%). Most of the patients were married, employees and housewives, aged between (20-30 yrs). Most patients use anxiolytics, muscle relaxants and proton pump inhibitor. There is a high IBS prevalence among low educational level (high school graduates and non-school graduates).Most patients in our study had constipation.Aggravating factors Psychological factors (stress) are intrinsically associated with IBS and symptoms in a large percentage of patients.Antispasmodics usage in our study show high effectiveness for IBS patients especially those with crampy abdominal pain and diarrhea.Conclusions: Diagnosing and managing IBS can be a big challenge since many drugs used to reduce symptoms and severity, but also, they could be unnecessary medication that could aggravate bowel symptoms and have adverse effects on the long term.


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