Computerised dynamic posturography for postural control assessment in subjects wearing multifocal contact lenses dedicated for myopia control

Author(s):  
Katarzyna Przekoracka ◽  
Krzysztof Piotr Michalak ◽  
Jan Olszewski ◽  
Andrzej Michalski ◽  
Anna Przekoracka‐Krawczyk
2021 ◽  
Vol 10 (4) ◽  
pp. 808
Author(s):  
Cristina Alvarez-Peregrina ◽  
Miguel Ángel Sánchez-Tena ◽  
Clara Martinez-Perez ◽  
Catalina Santiago-Dorrego ◽  
Thomas Yvert ◽  
...  

Background: Many epidemiological and experimental studies have established that myopia is caused by a complex interaction between common genetic and environmental factors. The objective of this study was to describe and compare the allelic and genotypic frequencies of the rs524952 (GJD2), rs8000973 (ZIC2), rs1881492 (CHRNG), rs1656404 (PRSS56), rs235770 (BMP2), and rs7744813 (KCNQ5) SNPs (single-nucleotide polymorphism) between responder and nonresponder patients who had undergone a two-year treatment with lenses for myopia control. Method: Twenty-eight participants from the MiSight Assessment Study Spain (MASS), who had received treatment for myopia control for two years with MiSight contact lenses, were examined. The criteria for better/worse treatment response was the change in the axial length (< / ≥ 0.22 mm two years after the treatment). The clinical procedure consisted of the extraction of a saliva sample, and the participants also underwent an optometric examination. Genetic data were analyzed using SNPStats software (Catalan Institute of Oncology, Barcelona, Spain), and statistical analysis was performed using SPSS v.25 (SPSS Inc., Chicago, IL, USA). Demographic variables were analyzed using the Student’s t-test. Results: The T allele, the one with the lowest frequency, of the “rs235770” SNP was associated with a better treatment response [AL/CR (axial length/corneal radius): OR = 3.37; CI = 1.079–10.886; SE (spherical equivalent): OR = 1.26; CI: = 0.519–57.169; p = 0.019). By performing haplotype analysis, significant differences were found between the rs235770…rs1881492 and rs235770–rs1656404 polymorphisms. The latter presented a strong linkage disequilibrium with each other (r2 ≥ 0.54). Conclusion: The result of lens therapies for myopia control could vary depending on genetic variants. Studies with a larger sample are needed to confirm the results presented in this pilot study.


2021 ◽  
pp. 548-554
Author(s):  
Nir Erdinest ◽  
Naomi London ◽  
Nadav Levinger ◽  
Yair Morad

The goal of this retrospective case series is to demonstrate the effectivity of combination low-dose atropine therapy with peripheral defocus, double concentric circle design with a center distance soft contact lenses at controlling myopia progression over 1 year of treatment. Included in this series are 3 female children aged 8–10 years with progressing myopia averaging −4.37 ± 0.88 D at the beginning of treatment. Their average annual myopic progression during the 3 years prior to therapy was 1.12 ± 0.75 D. They had not attempted any myopia control treatments prior to this therapy. The children were treated with a combination of 0.01% atropine therapy with spherical peripheral defocus daily replacement soft lenses MiSight<sup>®</sup> 1 day (Cooper Vision, Phoenix, AZ, USA). They underwent cycloplegic refraction, and a slit-lamp evaluation every 6 months which confirmed no adverse reactions or staining was present. Each of the 3 children exhibited an average of 0.25 ± 0.25 D of myopia progression at the end of 1 year of treatment. To the best of the authors’ knowledge, this is the first published study exhibiting that combining low-dose atropine and peripheral defocus soft contact lenses is effective at controlling children’s moderate to severe myopia progression during 1 year of therapy.


2009 ◽  
Vol 66 (S185) ◽  
pp. 162-166 ◽  
Author(s):  
T. Grosvenor ◽  
D. A. Goss

2005 ◽  
Vol 10 (5) ◽  
pp. 291-302 ◽  
Author(s):  
F. Mbongo ◽  
T. Patko ◽  
P.P. Vidal ◽  
N. Vibert ◽  
P. Tran Ba Huy ◽  
...  

2021 ◽  
Vol 137 (3) ◽  
pp. 5
Author(s):  
S.E. Avetisov ◽  
A.V. Myagkov ◽  
A.V. Egorova ◽  
Z.N. Poskrebysheva ◽  
O.A. Zhabina

1999 ◽  
Vol 9 (6) ◽  
pp. 445-451
Author(s):  
S. Di Girolamo ◽  
W. Di Nardo ◽  
A. Cosenza ◽  
F. Ottaviani ◽  
A. Dickmann ◽  
...  

The role of vision in postural control is crucial and is strictly related to the characteristics of the visual stimulus and to the performance of the visual system. The purpose of this investigation was to evaluate the effects of chronically reduced visual cues upon postural control in patients affected by Congenital Nystagmus (CN). These patients have developed since birth a postural strategy mainly based on vestibular and somatosensorial cues. Fifteen patients affected by CN and 15 normal controls (NC) were enrolled in the study and evaluated by means of dynamic posturography. The overall postural control in CN patients was impaired as demonstrated by the equilibrium score and by the changes of the postural strategy. This impairment was even more enhanced in CN than in NC group when somatosensorial cues were experimentally reduced. An aspecific pattern of visual impairment and a pathological composite score were also present. Our data outline that in patients affected by CN an impairment of the postural balance is present especially when the postural control relies mainly on visual cues. Moreover, a decrease in accuracy of the somatosensory cues has a proportionally greater effect on balance than it has on normal subjects.


2009 ◽  
Vol 2 (4) ◽  
pp. 215-222 ◽  
Author(s):  
Jacinto Santodomingo-Rubido ◽  
César Villa-Collar ◽  
Bernard Gilmartin ◽  
Ramón Gutiérrez-Ortega

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