Intra‐session repeatability of anterior chamber depth across the chamber width using Pentacam Scheimpflug imaging in healthy subjects

Abstract PurposeSlowing ectasia progression is critical for maintaining visual potential in keratoconus (KC), for which various therapeutic approaches have been implemented. We used a Pentacam Scheimpflug imaging device to quantify contact lens (CL)-related changes in keratoconic corneal topographic indices.MethodsThirty KC patients (group 1; 60 eyes) were using one of the three CL (rigid gas-permeable CL (RGPCL)-10; hybrid CL (HCL)-10; and scleral CL (SCL)-10 patients). A control group included 30 KC patients (group 2; 60 eyes) not using CLs due to intolerance or inappropriateness. The Pentacam® HR Scheimpflug imaging device was used to measure topographical indices such as Km anterior, Km posterior, K max, corneal thickness (CT; corneal central, apex, and thinnest), corneal volume (CV), anterior chamber volume (ACV), and anterior chamber depth (ACD) at baseline, 3rd, 6th, and 12th months.ResultsMean ages for groups 1 and 2 were 32 ± 10 and 31 ± 90 years, respectively. Group 1 had lower but statistically significant change in K max than group 2 (p < 0.038). Also, group 1 had a minor but non-significant decrease in anterior and posterior keratometry values compared to group 2 (pKm ant. right/left eye = 0.063/0.065 and 0.087/0.094, respectively). RGPCL users had significant changes in central CT, thinnest CT and ACD (p < 0.041). SCL users had more stable changes than other CLs for the thinnest CT along with significant changes in K max, pachy apex and ACV (p < 0.036). HCL users had significantly higher K max stability (p < 0.039).ConclusionRegular use of appropriate therapeutic CLs may help to stabilize corneal deformity, thereby slowing changes in corneal topographic indices in KC.

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Changes in anterior segment parameters of normal subjects during accommodation using a Scheimpflug imaging system

Medical Hypothesis, Discovery & Innovation in Optometry ◽

10.51329/mehdioptometry117 ◽

2021 ◽

Vol 1 (3) ◽

pp. 124-128

Author(s):

Yadav Jitendra ◽

De Tapas Kumar ◽

Sah Sanjay Kumar ◽

Anyam Sandip Das

Keyword(s):

Anterior Chamber ◽

Imaging System ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Maximum Amplitude ◽

Applanation Tonometry ◽

Angle Closure ◽

Cross Sectional ◽

Scheimpflug Imaging ◽

Anterior Segment Parameters

Background: Accommodation changes ocular parameters, such as the anterior chamber volume (ACV), anterior chamber depth (ACD), anterior chamber angle (ACA), and pupil diameter (PD), which can reflect a risk of angle-closure glaucoma. Previous studies of changes in ocular anterior segment parameters, have used high diopters or maximum amplitude. Here, we focused on normal accommodation at a reading distance of 30‒40 cm. The aim of this study was to assess changes in anterior segment parameters during a normal accommodative state, using a Scheimpflug imaging system. Methods: In this cross-sectional study, 40 emmetrope subjects (mean ± SD of age: 22 ± 4.0 years) who met the inclusion criteria and provided informed consent were enrolled. Clinical history, refraction, amplitude of accommodation, slit lamp examination, Goldman applanation tonometry, and Pentacam investigations were performed on all subjects. Accommodative and non-accommodative targets were induced via the Pentacam. Two seconds were allowed for accommodation or relaxation prior to measurements in each eye. Results: Eighty normal eyes were evaluated; a small but statistically significant change in ACV, ACA, and PD during accommodation (P < 0.01, < 0.01, and < 0.05, respectively) was observed. The ACD did not change substantially with accommodation (P = 0.29). The mean ± SD values of ACV, ACD, ACA, and PD before and after accommodation were 151.85 ± 24.04 mm3 and 145.38 ± 23.30 mm3, 2.87 ± 0.28 mm and 2.86 ± 0.27 mm, 35.06° ± 3.68° and 33.84° ± 3.72°, and 3.46 ± 0.57 mm and 3.41 ± 0.53 mm, respectively. Conclusions: Accommodation changes ocular parameters, such as ACV, ACA, and PD, in healthy young emmetropes. Interestingly, the ACD remains unaltered during accommodation. Nevertheless, although these changes were statistically significant, they were not clinically significant in our study.

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Management of Anterior Chamber Depth After Trabeculectomy

American Journal of Ophthalmology ◽

10.1016/0002-9394(88)90737-4 ◽

1988 ◽

Vol 106 (6) ◽

pp. 767-768 ◽

Cited By ~ 1

Author(s):

RICHARD J. MACKOOL ◽

JORGE N. BUXTON

Keyword(s):

Anterior Chamber ◽

Anterior Chamber Depth

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Polypharmacy-associated potential contraindications of drug prescriptions in patients with primary angle closure disease in a real-world setting

Journal of Pharmaceutical Health Care and Sciences ◽

10.1186/s40780-021-00196-w ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Fumiaki Tanaka ◽

Naoki Shibatani ◽

Kazumi Fujita ◽

Hiroaki Ikesue ◽

Satoru Yoshimizu ◽

...

Keyword(s):

Intraocular Pressure ◽

Anterior Chamber ◽

Anterior Chamber Depth ◽

Japanese Patients ◽

Median Number ◽

Angle Closure ◽

Primary Angle Closure ◽

Primary Angle Closure Glaucoma ◽

Number Of Patients ◽

Multiple Drugs

Abstract Background Primary angle closure disease (PACD) is a type of glaucoma in which the intraocular pressure (IOP) is increased because of the blockage of the anterior chamber angle. Medications contraindicated for patients with PACD, such as anticholinergics, cause mydriasis, and can elevate IOP. However, anticholinergics are currently contraindicated only for primary angle closure glaucoma (PACG) in Japanese package inserts. In this study, we investigated the prescription status of medications contraindicated for PACD, such as anticholinergics, in patients with PACD scheduled for eye surgeries. Methods Forty-three Japanese patients diagnosed with PACD at Kobe City Eye Hospital, Japan, and scheduled hospitalization for eye surgeries between December 2017 and July 2018, were included. Data, including sex, age, diagnosis, IOP, anterior chamber depth, and patients’ regular medications prior to hospitalization, were collected for each patient from the electronic medical records. Results The number of patients with chronic primary angle closure (CPAC) and acute primary angle closure (APAC) was 35 (81.4%) and 8 (18.6%), respectively. Among all the 43 patients with PACD, 8 (18.6%) received 15 medications that are potentially contraindicated for PACD by non-ophthalmologist. According to medication categories, benzodiazepine hypnotics were the most commonly prescribed. Among the 8 patients with APAC, 2 (25.0%) had routinely received medications contraindicated for PACD. The median number of all kinds of prescriptions on the day of hospitalization was significantly higher for patients who received medications contraindicated for PACD than for those who did not receive them (p = 0.010). Conclusions About 20% of patients with PACD received medications potentially contraindicated for PACD, such as anticholinergics. Attention should be paid to patients prescribed multiple drugs for adverse events, such as increase in intraocular pressure.

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Relationship between intraocular pressure, anterior chamber depth and lens thickness in primary open-angle glaucoma patients

International Ophthalmology ◽

10.1007/s10792-017-0488-4 ◽

2017 ◽

Vol 38 (2) ◽

pp. 541-547 ◽

Cited By ~ 2

Author(s):

Bolajoko A. Adewara ◽

Bernice O. Adegbehingbe ◽

Oluwatoyin H. Onakpoya ◽

Chidi G. Ihemedu

Keyword(s):

Intraocular Pressure ◽

Anterior Chamber ◽

Primary Open Angle Glaucoma ◽

Open Angle Glaucoma ◽

Anterior Chamber Depth ◽

Open Angle ◽

Lens Thickness

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Intraocular Pressure Reduction after Femtolaser Assisted Cataract Surgery and Its Association with the Use of Ultrasound

Medicina ◽

10.3390/medicina57050437 ◽

2021 ◽

Vol 57 (5) ◽

pp. 437

Author(s):

Hana Abouzeid ◽

Walter Ferrini ◽

Murielle Bochud

Keyword(s):

Intraocular Pressure ◽

Linear Regression ◽

Cataract Surgery ◽

Anterior Chamber ◽

Anterior Chamber Depth ◽

Multiple Linear Regression Model ◽

Study Data ◽

Department Of Ophthalmology ◽

Duration Of Surgery ◽

Ocular Pressure

Background and Objectives: To quantify the change in intraocular pressure (IOP) after phacoemulsification in patients having undergone femtolaser assisted cataract surgery (FLACS), and study the influence of the use of ultrasound on this change. Setting: Jules-Gonin Eye Hospital, University Department of Ophthalmology, Lausanne, Switzerland. Materials and Methods: Interventional study. Methods: All consecutive cases operated with FLACS and with complete data for the studied parameters were selected for inclusion in the study. Data had been prospectively collected and was analysed retrospectively. Linear regression was performed to explore the association of change in IOP with time of measure, ultrasound use, sex, age, and duration of surgery. Results: There was a mean decrease in intraocular pressure of 2.5 mmHg (CI 95% −3.6; −1.4, p < 0.001) postoperatively. No association between the change in intraocular pressure and ultrasound time or effective phaco time was observed when the data were analyzed one at a time or in a multiple linear regression model. There was no association with sex, age, nuclear density, presence of pseudoexfoliation, duration of surgery, and time of ocular pressure measurement. Eyes with preoperative IOP ≥ 21 mmHg had a more significant IOP reduction after surgery (p < 0.0001) as did eyes with an anterior chamber depth <2.5 mm (p = 0.01). Conclusion: There was a decrease in intraocular pressure six months after FLACS in our study similar to that in the published literature for standard phacoemulsification. The use of ultrasound may not influence the size of the decrease, whereas the preoperative IOP and anterior chamber depth do. FLACS may be as valuable as standard phacoemulsification for cases where IOP reduction is needed postoperatively.

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Changes in anterior segment optical coherence tomography following pars plana vitrectomy without tamponade

International Journal of Retina and Vitreous ◽

10.1186/s40942-021-00285-w ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Alireza Khodabande ◽

Massood Mohammadi ◽

Hamid Riazi-Esfahani ◽

Shahab Karami ◽

Massood Mirghorbani ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Pars Plana Vitrectomy ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Optical Coherence ◽

Mean Values ◽

Iop Measurement ◽

Pars Plana ◽

The Mean

Abstract Background To evaluate changes in anterior segment morphology on anterior segment optical coherence tomography (AS-OCT) following pars plana vitrectomy (PPV) without tamponade. Methods Patients who underwent PPV without tamponade for epiretinal membrane were evaluated. Eligible patients underwent intraocular pressure (IOP) measurement and AS-OCT preoperatively as well as 1 month and 6 months post-operatively. Anterior chamber width (ACW), anterior chamber depth (ACD), trabecular iris angle (TIA), angle opening distance at 500 and 750 µm (AOD), and trabecular iris space area at 500 and 750 µm (TISA) at four quadrants were recorded and analyzed. Additionally, the mean values of TIA (MTIA), AOD (MAOD), and TISA (MTISA) for each eye (mean of four quadrants) were analyzed. Results 23 patients completed the study. The mean age of participants was 56.4 ± 3.6 years of age and 13/23 (56%) were female. Mean IOP of patients was 18.1 ± 1.1, 18.3 ± 1.1, and 18.1 ± 1.2 preoperatively,1 month post-operatively, and 6 months post-operatively, respectively. (p = 0.83). No difference was detected post-operatively in measurements of ACW, ACD, MTIA, MAOD500, MAOD750, MTISA500, and MTISA750. Conclusion Pars plana vitrectomy without tamponade was not associated with changes in anterior chamber morphology.

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